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Systematic Review and Meta-Analysis: Effect of Zinc Levels in COVID-19 Patients on Their Clinical Severity Annisa, Ika Nur; Yuniasih, Dewi; Sukirto, Novi Wijayanti
Ahmad Dahlan Medical Journal Vol. 4 No. 2 (2023): November 2023
Publisher : Universitas Ahmad Dahlan

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Abstract

Background: COVID-19 is a new type of Coronavirus that can cause ARDS and make it a worldwide pandemic. Treatment for COVID-19 is based on the clinical severity of COVID-19. Zinc has anti-inflammatory, antiviral, and antioxidant effects given as an adjuvant therapy for the treatment of COVID-19. Prolonged zinc deficiency is a risk factor for severe COVID-19. Methods: This systematic review and meta-analysis study used 4 databases namely ScienceDirect, Cochrane Library, ProQuest, and PubMed. The keywords used are “Zinc” OR “Severity COVID-19” AND “Zinc Deficiency” OR “Mortality COVID-19” AND “Zinc” OR “Clinical Severity COVID-19” AND “Zinc Deficiency” OR “Clinical Severity COVID- 19”. The articles identified are articles that are relevant to the title of research, published internationally, accessed free of charge, published between 2019-2021, published in accredited journals Results: Out of 8,330 article titles, 944 were excluded due to double counting in each database. A total of 7,371 articles were excluded because they did not match the title of the study, did not match the research method, used another language, did not match the year of publication. A total of 15 articles were included in the qualitative synthesis. Five studies were included in the meta-analysis. Three studies were analyzed with the results that the average zinc level of COVID-19 patients was not much different from that of healthy patients with a mean difference of 1.73 (95% CI -39.14-42.60). Two studies were analyzed with low zinc levels in patients with severe COVID-19 associated with the need to enter the intensive care unit with an OR of 3.62 The SARS-CoV-2 virus spreads through droplets that are expelled while coughing or sneezing. Conclusion: The average zinc level of COVID-19 patients is not different from that of healthy patients, but low zinc levels in patients with severe COVID-19 are associated with the need to enter the intensive care unit.
SYSTEMATIC REVIEW OF THE EFFICIENCY OF TELEMEDICINE DURING THE COVID-19 PANDEMIC Yuniasih, Dewi; Mansur, Auliya Azisah; Dewantari, Aulia Nissa; Dewantari, Aulia Yasmin; Annisa, Ika Nur; Susilawati, Okti
Muhammadiyah International Public Health and Medicine Proceeding Vol. 2 No. 1 (2022): PROCEEDING MUHAMMADIYAH INTERNATIONAL PUBLIC HEALTH AND MEDICINE CONFERENCE - S
Publisher : Fakultas Kesehatan Masyarakat Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.346 KB) | DOI: 10.61811/miphmp.v1i2.287

Abstract

COVID-19 is a world health problem that has caused significant changes in the health care system. During the COVID-19 pandemic, some efforts are needed to reduce the spread of the. Telemedicine, as a remote technology, is one of the effective options for use in the healthcare system today. This study aims to explore the efficiency of using telemedicine as one of the facilities in the context of controlling COVID-19. This systematic review research uses 4 databases: PubMed, ScienceDirect, ProQuest, and Wiley. The keywords used are "telemedicine" or "telehealth," "e-Health," and "COVID-19". The inclusion criteria are the articles that contain telemedicine in the control of COVID-19, published in 2021 in Indonesian or English by accredited journals, and using observational, descriptive, or case research. About 1,877 article titles were identified, and 1,869 were excluded because they were irrelevant and did not match the inclusion factor. A total of 8 articles were included in the analysis of this study. One article found that the effectiveness of telemedicine for rural communities is difficult to access. Six articles found that telemedicine reduces the frequency of visits to doctors/hospitals, reduces transportation costs, reduces hospitalization time and costs, reduces the workload of health workers, and reduces the transmission of COVID-19. One article listed the effectiveness of telemedicine for COPD patients with COVID-19. Telemedicine as a health care system is a promising effort during the COVID-19 pandemic and has excellent potential to help reduce the burden of health costs.