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All Journal Ahmad Dahlan Medical Journal
Sukirto, Novi Wijayanti
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Systematic Review and Meta-Analysis: Effect of Zinc Levels in COVID-19 Patients on Their Clinical Severity Annisa, Ika Nur; Yuniasih, Dewi; Sukirto, Novi Wijayanti
Ahmad Dahlan Medical Journal Vol. 4 No. 2 (2023): November 2023
Publisher : Universitas Ahmad Dahlan

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Background: COVID-19 is a new type of Coronavirus that can cause ARDS and make it a worldwide pandemic. Treatment for COVID-19 is based on the clinical severity of COVID-19. Zinc has anti-inflammatory, antiviral, and antioxidant effects given as an adjuvant therapy for the treatment of COVID-19. Prolonged zinc deficiency is a risk factor for severe COVID-19. Methods: This systematic review and meta-analysis study used 4 databases namely ScienceDirect, Cochrane Library, ProQuest, and PubMed. The keywords used are “Zinc” OR “Severity COVID-19” AND “Zinc Deficiency” OR “Mortality COVID-19” AND “Zinc” OR “Clinical Severity COVID-19” AND “Zinc Deficiency” OR “Clinical Severity COVID- 19”. The articles identified are articles that are relevant to the title of research, published internationally, accessed free of charge, published between 2019-2021, published in accredited journals Results: Out of 8,330 article titles, 944 were excluded due to double counting in each database. A total of 7,371 articles were excluded because they did not match the title of the study, did not match the research method, used another language, did not match the year of publication. A total of 15 articles were included in the qualitative synthesis. Five studies were included in the meta-analysis. Three studies were analyzed with the results that the average zinc level of COVID-19 patients was not much different from that of healthy patients with a mean difference of 1.73 (95% CI -39.14-42.60). Two studies were analyzed with low zinc levels in patients with severe COVID-19 associated with the need to enter the intensive care unit with an OR of 3.62 The SARS-CoV-2 virus spreads through droplets that are expelled while coughing or sneezing. Conclusion: The average zinc level of COVID-19 patients is not different from that of healthy patients, but low zinc levels in patients with severe COVID-19 are associated with the need to enter the intensive care unit.
The Effect of Health Education on Knowledge of the Dangers of Smoking in Students of SMK Negeri 4 Yogyakarta Prisilla Maya Heni Pratiwi; Putri, Rachma Greta Perdana; Sukirto, Novi Wijayanti; Astuti, Fardhiasih Dwi
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

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Smoking is the activity of smoking tobacco rolls wrapped in paper or nipa leaves and then burning and producing smoke. In thesurvey results of the Ministry of Health of the Republic of Indonesia, the risk of smoking behavior in junior and senior high school students in Indonesia in 2015 was 32.82% in male students. Smoking habits lead to health risk for cardiovascular and respiratory diseases and many types of cancer. Smokers have moderate knowledge of tobacco. The study's aim is to examine the effect of health education on knowledge of the dangers of smoking in students of SMK Negeri 4 Yogyakarta. This study utilized a pre-experimental design method with One-Group Pretest-Posttest design approach. The study sample consisted of 127 students who met inclusion and exclusion criteria in class X students of SMK Negeri 4 Yogyakarta. The pretest and post-test scores varied from 22 to 29 with increased scores of the post-test’s trend. Statistical analysis using chi-square test analysis showed a p-value of 0.000 (<0.05). These results suggest that there is an influence between health education on knowledge of the dangers of smoking in students of SMK Negeri 4 Yogyakarta
Length of Hospitalization and Clinical Outcomes for Pneumonia Patients at PKU Muhammadiyah Hospital, Bantul Umam Kurniawan, Nurcholid; Sukirto, Novi Wijayanti; Prisilla, Elvina; Rahayu, Ana Budi; Yuniasih, Dewi; Ari Mulyani, Dewi; Ulfa, MH Muflihatul
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

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Pneumonia is a lower respiratory tract infection that was the leading cause of death in developing countries in 2020, it was shown that pneumonia was the largest contributor to post-neonatal (14.5%) and under-five deaths (5.05%). The timing of hospital discharge for patients with pneumonia is determined primarily by the attending physician and is based on an assessment of the patient's clinical stability and the appropriate duration of inpatient medical therapy. The patient's discharge decision determines the length of hospital stay. Objective: To determine the length of hospitalization and clinical outcome improvement of pneumonia patients at PKU Muhammadiyah Bantul Hospital. Methods: This study was a cross-sectional descriptive study using a retrospective study conducted by taking medical record data at PKU Muhammadiyah Bantul Hospital Results: Pneumonia patients at PKU Muhammadiyah Bantul Hospital were dominated by the age group of 2 years old while by gender the majority were boys. Length of Stay (LOS) of pneumonia patients was highest with three days of treatment as many as 136 patients or 54.2%. Conclusion: Cumulatively within seven days, 98.80% of pneumonia patients showed good clinical outcomes and were allowed to leave the hospital. it is not known for certain that patient outcomes are related to the patient's length of stay because all patients returned home in improved condition after treatment at the hospital.
Stroke Hemorrhagic after Snakebite: A Scoping Review Budi Rahayu, Ana; Yuniasih, Dewi; Sukirto, Novi Wijayanti; Hikmawan Yuliarto Benni Sambada, Taufiek; Selohandono, Andrianto
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

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Snakebite envenomation is a neglected tropical disease that affects millions of individuals living in underdeveloped countries. Cerebral complications are often found in venomous snake bite victims. Certain snake venoms can interfere with the blood's ability to clot, increasing the risk of bleeding in the brain and potentially causing a stroke. previous literature review studies have not comprehensively reviewed stroke hemorrhagic after snake bites. Therefore, we are interested in conducting a literature review using the scoping review method on stroke hemorrhagic after snake bites. The samples in this study were published articles from international journals related to cerebral complications after snakebite that met the inclusion and exclusion criteria. The inclusion criteria used in this study were articles derived from the PubMed, ScienceDirect, and Scopus databases, using the keywords “Snakebite” OR “Snake envenoming” AND “Stroke hemorrhagic”. Based on the eligibility, Six articles were finally synthesized in the study. All of papers were a case report design. Three cases were from Brazil, three cases from Morocco, Burkina Faso and Togo. The snake that causes hemorrhagic stroke in Brazil is Bothropp spp. however, the type of snake in the instances from Burkina Faso and Morocco is unknown. There were a total of 10 instances reported from 6 journals. One patient from Morocco died, while another patient from Brazil suffered from prolonged hemiplegia. Furthermore, a total of 8 more patients were released from the hospital in an improved condition.
Utilization of Xpert MTB/RIF molecular test and Thorax Radiography as Tuberculosis Screening at PKU Muhammadiyah Bantul Hospital Prisila, Elvina; Sukirto, Novi Wijayanti; Umam Kurniawan, Nurcholid; Rahayu, Ana Budi; Yuniasih, Dewi; Wira Oktaviana, Ardyawati; Putri Nurulita, Febrianti; Sholikhah, Amanatus; Awisarita, Wiwara
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

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Tuberculosis is a disease caused by the bacteria Mycobacterium tuberculosis, and approximately 25% of the global population is afflicted with this bacterium. In 2022,The objective of this study is to assess the effectiveness of the Xpert MTB/RIF Molecular Test and Thorax Radiography as diagnostic tools for tuberculosis at PKU Muhammadiyah Bantul Hospital. The research employed quantitative methodologies with a cross-sectional design. The majority of tuberculosis suspects at PKU Muhammadiyah Bantul Hospital were individuals aged 64 years or older, based on age group. In terms of gender, 498 individuals were male. According to the Xpert MTB/RIF molecular test, 89 individuals tested positive for tuberculosis. In contrast, the number of individuals who tested positive for tuberculosis through thorax photo examination was 184. The findings indicate that the majority of patients suspected of having Tuberculosis were males and were primarily in the age category of above 64 years old. Thorax photo radiography yielded a higher number of confirmed positive tuberculosis findings compared to the Xpert MTB/RIF molecular test, based on the evaluation of individuals suspected of having tuberculosis.
Co-Authors Annisa, Ika Nur Ari Mulyani, Dewi Awisarita, Wiwara Budi Rahayu, Ana Fardhiasih Dwi Astuti Hikmawan Yuliarto Benni Sambada, Taufiek Prisila, Elvina Prisilla Maya Heni Pratiwi Prisilla, Elvina Putri Nurulita, Febrianti Putri, Rachma Greta Perdana Rahayu, Ana Budi Selohandono, Andrianto Sholikhah, Amanatus Ulfa, MH Muflihatul Umam Kurniawan, Nurcholid Wira Okta Viana Yuniasih, Dewi