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Sagia, Nabilla Alsa
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Education Medicine & Pharmacology Neuroscience Public Health

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Faktor-faktor yang Mempengaruhi Keberhasilan Terapi Pasien Kusta Sagia, Nabilla Alsa; Anggraini, Dwi Indria; Wulan, Anggraeni Janar; Sibero, Hendra Tarigan
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.937

Abstract

Leprosy is a chronic granulomatous infectious disease caused by the obligate intracellular bacterium Mycobacterium leprae (M. leprae). This disease comes from the Latin word "lepros" which means scale. M. Leprae bacteria enter the human body through 2 main routes, namely through the skin and the upper respiratory tract. Leprosy bacilli enter the human body through direct contact with the skin or nasal mucosa originating from droplets. Bacteria from droplets will survive for 2 days in a dry environment, even up to 10 days in a humid environment and low temperatures. The success of therapy for Morbus Hansen patients is expressed by RFT (Release from Treatment). RFT can be stated after the dose is fulfilled without having to undergo laboratory examination. PB (paucibacillary) patients who have received 6 doses (blister) of treatment within 6-9 months are declared RFT, without having to undergo a laboratory examination. MB (multibacillary) patients who have received 12 doses (blister) of MDT treatment within 12-18 months are declared RFT, without having to undergo a laboratory examination. The factors that play a role in the success of therapy for leprosy patients are age, gender, education, employment, knowledge, compliance with taking medication, and family support.
Laporan Kasus: Pendekatan Multidisiplin dalam Manajemen Ketuban Pecah Dini pada Kehamilan Kembar Rahmatullah, Muhammad Rayza; Sagia, Nabilla Alsa; Zahra, Tsurayya Fathma; Zulfadli, Zulfadli
Medula Vol 14 No 6 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i6.1136

Abstract

Twin pregnancies are high-risk conditions often accompanied by various complications, one of which is premature rupture of membranes (PROM). PROM is the rupture of the amniotic membrane before the onset of labor, occurring either before 37 weeks of gestation (preterm) or after (term). PROM significantly contributes to preterm births, a leading cause of global neonatal mortality. In Indonesia, the incidence of PROM increased from 13.1% in 2020 to 14.6% in 2021. This case study reports on a 36-week pregnant woman with twins who experienced PROM and successfully delivered vaginally with favorable outcomes for both the mother and neonates. The diagnosis of PROM was confirmed through anamnesis, physical examination, and supporting tests. Management included intensive observation, intravenous fluid administration, antibiotics, and antenatal steroids for fetal lung maturation. Previous research indicates that twin pregnancies significantly increase the risk of PROM. Key risk factors for PROM include a history of PROM, short cervical length, and low socio-economic status. Management of PROM in twin pregnancies involves the administration of antenatal steroids, latency antibiotics, magnesium sulfate for neuroprotection, and rigorous clinical and ultrasonographic monitoring. Diagnosis is performed via speculum examination and immunochromatographic tests. In conclusion, appropriate and effective management of PROM in twin pregnancies is crucial for improving pregnancy outcomes and reducing the risk of complications for both mother and infants.
Co-Authors Anggraeni Janar Wulan, Anggraeni Janar Dwi Indria Anggraini Hendra Tarigan Sibero Rahmatullah, Muhammad Rayza Zahra, Tsurayya Fathma Zulfadli Zulfadli