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Nanoemulsion Formulation Combination of Virgin Coconut Oil (VCO) and Candlenut Oil (Alleurites mollucanus) for Hair Growth in Male White Rats (Rattus novergicus) Lasanudin, Rindi Ibrahim; Bachri, Mochamad Saiful; Wahyuningsih, Iis; Efiana, Nur Ari
Pharmacon: Jurnal Farmasi Indonesia Vol. 21 No. 1 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i1.4348

Abstract

Having healthy and thick hair is the dream of many people, but some people have problems related to their hair. Hair problems that often occur are hair loss, thin hair or baldness, so to overcome these problems hair growth products have been made. Virgin Coconut Oil VCO and candlenut oil can be used as natural ingredients that can grow hair. The aim of this research was to determine the best nanoemulsion formulation for a combination of candlenut oil and VCO; and to determine the difference between applying nanoemulsion, conventional candlenut oil, conventional VCO and the oil emulsion on hair growth in male rats. This nanoemulsion formulation uses a combination of candlenut oil and VCO in a ratio of 1:1, 1:3 and 3:1. The nanoemulsion obtained was subjected to organoleptic, pH, viscosity, flow type and % transmittance. The best formulation was then tested for droplet size and zeta potential as well as hair growth activity tests using male rats. It was found that the best nanoemulsion formula was a nanoemulsion with a combination of 1:3 with a yellow color, a distinctive odor and clear with a droplet size of 14.42 ± 0.03 nm, a zeta value of -27.8 ± 1.02 mV, the length of the hair produced in the test hair growth activity was 17.14 ± 0.42 mm and hair weight was 699.37 ± 7.91 mg.
The Description of Knowledge and Attitude of Coffee Lovers on Diabetes Melitus At Coffee Shops In Palaran District: The Description of Knowledge and Attitude of Coffee Lovers on Diabetes Melitus At Coffee Shops In Palaran District Ma'ruf, Muhammad; Setianto, Arif Budi; Lasanudin, Rindi Ibrahim; Yuliani, Sapto
KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat Vol 9 No 2 (2023): December
Publisher : Universitas Widya Gama Mahakam Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24903/kujkm.v9i2.2224

Abstract

Background: Diabetes mellitus is a disease that is often called "the silent killer." This disorder occurs in the metabolism of carbohydrates and fats that are relatively deficient in insulin in the body. Previous research said that coffee could be used as a therapy for diabetes mellitus. The background for writing this article is the high prevalence of knowledge and attitude of coffee lovers and scientific evidence of coffee content as a decrease in blood glucose levels. Objectives: This study aims to describe the knowledge and attitude of coffee lovers toward diabetes mellitus in coffee shops in Palaran District. Research Metodes: This research method uses quantitative and descriptive. Data were obtained by distributing questionnaires to research subjects, namely coffee lovers who were in coffee shops in the Palaran District, Samarinda City, totaling 46 respondents. Results: The results showed that there were 26 coffee lovers (56.5%) who had good knowledge of diabetes mellitus and 20 people (43.5%) who had a good understanding of diabetes mellitus. Meanwhile, in the attitude of coffee lovers, there were 35 people (76.1%) who had good attitude towards diabetes mellitus and 11 people (23.9%) who had a reasonably good attitude towards diabetes mellitus. Conclusion: It can be concluded that the coffee lovers in the Palaran District coffee shop, on average, have good knowledge and attitude towards diabetes mellitus.
Formulation of lotion ethanolic extract of rosella flower petals (Hibiscus sabrariffa L.) and antioxidant activity Fadli, Justitia Cahyani; Lasanudin, Rindi Ibrahim
Journal of Halal Science and Research Vol. 5 No. 1 (2024): February
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v5i1.7151

Abstract

Rosella flowers (Hibiscus sabrariffa L.) are plants that are useful as antioxidants. The content that acts as an antioxidant is a flavonoid compound. This study aimed to determine the effect of giving calliandra honey as a multiple active ingredient and single active ingredient (rosella petal extract, calliandra honey )  and ethyl vitamin C as an active ingredient. The lotion of ethanolic extract of rosela flower petals was made with three active ingredients: ethanolic extract of roselle flower petals with a concentration of 2.5%, calliandra honey 2.5%, and ethyl vitamin C 2%. Then, calliandra honey and ethanol extract of roselle flowers are combined with a concentration of extract 2.5% and calliandra honey (1.5%, 2%, and 2.5%). The physical and stability tests are the organoleptic, homogeneity, viscosity, dispersibility, pH, lotion stability, and the value of lotion's antioxidant activity. The activity test was carried out using the 2,2-Diphenyl-1-Picryhidrazil (DPPH) method, and the IC50 of inhibition was calculated. The results of the study showed that all lotion formulations had antioxidant activity. The highest antioxidant activity was obtained in formula three, which had a value of 95.2 ppm (2.5: 2.5 %). Based on the Kruskal Wallis test, the asymp value was obtained. Sig. 0.000, which indicates that there is a significant difference in antioxidant activity. This is because the percent inhibition of each sample has a large enough difference.