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HEPATITIS B VIRUS INFECTED INDIVIDUALS' QUALITY OF LIFE AND RELATED FACTORS Ummi Maimunah; Ulfa Kholili; Amie Vidyani; Annisa Zahra Mufida; Diah Rizki Rahma Dini; Isna Mahmudah; Titong Sugiharto; Muhammad Miftahussurur
Journal of Scientech Research and Development Vol 6 No 1 (2024): JSRD, June 2024
Publisher : Ikatan Dosen Menulis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56670/jsrd.v6i1.422

Abstract

Globally, hepatitis B is a public health issue, and Indonesia is not an exception. We investigated a number of factors related to chronic hepatitis B patients' quality of life. Patients with Hepatitis B provided information to us through the WHO Quality of Life questionnaire. Data analysis conducted in this study was a chi-square test and a multivariate logistic regression model was used to calculate the odds ratios (OR). This study involved 31 people with varying quality of life. The average age range for good quality of life was 33 years, with 61.9% of patients being Javanese and 38.1% being Madurese. 70% of very good quality of life patients were Javanese, while 30% were Madurese. High school education was the most common, with 52.4% of patients having a good quality of life. Most patients worked as housewives, with 90.5% and 9.5% as factory employees. Hepatitis B control history was also a significant factor, with 57.1% of patients having never had it. Pregnancy status was 81% of patients with good quality of life, while 90% had no other diseases. Housewives with hepatitis B had a better quality of life than the others (P = 0.043). However, we could not find any association between age, ethnicity, education background, treatment, current pregnancy, and have other disease with quality of life (P = 0.645, P = 0.218, P = 0.417, P = 0.339, P = 0.133 and P = 0.419, respectively). This study reveals a significant relationship between occupation and the quality of life of hepatitis B patients, highlighting the importance of health-related quality of life in evaluating treatment and prognosis.
Strongyloides Colitis: Gastrointestinal Manifestation of Helminthiasis Resemble Inflammatory Bowel Disease Putri, Winni Aprillia; Mufida, Annisa Zahra; Sugihartono, Titong
Indonesian Journal of Tropical and Infectious Disease Vol. 14 No. 1 (2026): January - April Edition
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v14i1.78268

Abstract

Strongyloides stercoralis is an intestinal parasitic nematode classified as a Soil-Transmitted Helminth (STH) and estimated to infect up to 100 million people worldwide. The prevalence of STH is higher in tropical developing countries, such as Indonesia. This disease can manifest as a digestive tract infection, and in a few cases, also as colitis. Strongyloides colitis frequently exhibits clinical and endoscopic features that closely resemble those of  Inflammatory Bowel Disease (IBD), particularly Ulcerative Colitis (UC). Their resemblance could lead to diagnostic errors and also mistreatment.  Here we present a case of helminthiasis manifested as Strongyloides colitis in an at-risk elderly person from an endemic area. This study aims to highlight the complex diagnostic and treatment challenges to achieve a better prognostic outcome.  A 61-year-old female was referred with a history of prolonged diarrhea accompanied by worsening abdominal pain. The colonoscopy demonstrated features of helminth colitis. A single dose of an anthelmintic was administered, after which the patient showed progressive improvement within two weeks. Six months of follow-up after treatment showed satisfactory results. In typical symptoms of colitis, detection of the underlying cause is very important. This uncommon case report is intended as an alert to avoid further misdiagnosis of helminth colitis from UC, since the cure rate is relatively high with appropriate medication. Further discussions on initial diagnostic tools and comprehensive treatment are needed, along with integration into global helminth control strategies.
Self-Expandable Metallic Stent Placement for Radiation-Induced Esophageal Stricture: A Case Report Annisa Zahra Mufida; Amie Vidyani; Andi Ratna Kartika Maharani; Amal Arifi Hidayat; Titong Sugihartono
Asian Journal of Healthcare Analytics Vol. 5 No. 1 (2026): May 2026
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajha.v5i1.15847

Abstract

Radiation-induced esophageal stricture (RIES) represents a severe late complication in patients receiving radiotherapy, resulting in progressive dysphagia that can significantly impair quality of life. Several therapeutic options exist, including endoscopic dilation, injection therapy, incision, self-dilatation, surgical correction, and temporary stent placement. Among these, temporary esophageal stenting offers the potential advantage of providing sustained luminal expansion, stimulating tissue remodeling, and achieving long-term symptom relief. A 47-year-old woman with stage IV breast carcinoma and a prior history of radiotherapy presented with progressive difficulty swallowing. Over three months, her dysphagia worsened from solids to liquids. Endoscopic evaluation revealed a 4 cm esophageal stricture. Initial CRE balloon dilation improved her symptoms temporarily, but recurrence occurred, prompting a repeat endoscopy with adjunctive corticosteroid injection. Due to the relapse, a fully covered self-expandable metallic stent (SEMS) was placed to minimize the need for repeated dilations. The procedure was completed without complications. The management of benign esophageal strictures aims to reestablish luminal patency and alleviate dysphagia. SEMS placement represents an effective and reliable therapeutic option, particularly in cases of radiation-induced stricture where balloon dilation alone fails to achieve lasting results.