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All Journal Indonesian Journal of Tropical and Infectious Disease Jurnal Ilmiah Kedokteran Wijaya Kusuma Health Notions Jurnal Ilmiah Universitas Batanghari Jambi Journal of Maternal and Child Health INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Care : Jurnal Ilmiah Ilmu Kesehatan Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat Biomolecular and Health Science Journal Journal of Telenursing (JOTING) Jurnal Layanan Masyarakat (Journal of Public Service) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL Narra J Journal Of Sustainability Perspectives Journal of Scientech Research and Development The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Journal of Sustainability Perspectives Proceeding Of International Conference On Education, Society And Humanity Jurnal Greenation Sosial dan Politik

Muhammad Miftahussurur

Departemen Penyakit Dalam, Rumah Sakit Dr. Seotomo, Jl. Mayjen Prof. Dr. Moestopo No.6-8, Surabaya 60286, Indonesia

Author-ID : 629095

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Ketogenic Diet Slows Down Weight Gain in Juvenile Mus musculus with Benzopyrene as Cancer Inducer Dita Mega Utami; Lilik Herawati; Reny I’tishom; Mohammad Anam Al-Ari; Muhammad Miftahussurur; Purwo Sri Rejeki
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14709

Objective: This study aims to analyze the ketogenic diet that slows down weight gain in juvenile Musmusculus induced with benzopyrene (BZP). Method: Thirty-six female mice (Mus musculus), 6-8 weeks old,weighted 15-25 grams were divided into six groups randomly. K1 (negative control, standard diet) inducedwith oleum olivarum, while K2 (positive control, standard diet), P1 (ketogenic diet 1), P2 (ketogenic diet 2),P3 (ketogenic diet 3) and P4 (ketogenic diet 4) induced with BZP subcutaneously in the right breast at a doseof 0.3mg/20gBB/day for 14 days. The ketogenic diet was given for the next 28 days. Data were analyzedusing the ANOVA and post hoc LSD test. Results: After 42 days, the ketogenic diet mice experiencedslower weight gain (p=0.000) because BZP induced neurotoxicity and the administration of the ketogenicdiet in juvenile mice induced neurohormonal changes. The ketogenic diet increased ketone plasma level(p=0.000) and reduced blood glucose levels (p=0.002) due to nutritional ketosis state. Conclusions: Theketogenic diet with fat:protein ratio 60:30 slows down weight gain, increased ketone levels and decreasedblood glucose levels in juvenile mice with BZP as cancer inducer.

Exercise Intensity May affect Bdnf Level in the Hippocampus of Fructose-Induced Mice Misbakhul Munir; Muhammad Miftahussurur; Adi Pranoto; Purwo Sri Rejek
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15864

Introduction – Several studies show that there is a negative correlation between obesity and cognitive function. Exercise can reverse the bad effect of obesity through mediation of BDNF. Research about the effect of exercise intensity to BNDF levels in hippocampus of mice is ever be done, but research about the effect of exercise intensity to BNDF levels in hippocampus of fructose-induced mice is never be done.Objective – To prove the effect of different exercise intensity to BDNF level in hippocampus of fructoseinduced mice. Methods – A total of 32 mice were divided into four groups: Control group which was a CON and treatment groups which were low-intensity exercise (LIE), moderate-intensity exercise (MIE), and high-intensity exercise (HIE). The duration of treatment was 4 weeks. Swimming to exercise held 3 times a week and fructose solution dose was 270 grams for 9 days.Results – This research revealed that there was significantly difference on body weight before and after administration of fructose solution for 9 days (p=0.000). The lowest BDNF levels after treatment was group C and the highest of BDNF levels was group MI. There was no significantly difference in BDNF levels among groups after treatment (p=0.378), but there was tendency for BDNF levels to increase with exercise intensity.Conclusion – Swimming exercise with low-intensity, moderate-intensity, and high intensity has no effect on BDNF level in the hippocampus of fructose-induced mice.

Moderate Intensity Exercise is Most Influential in The Expression of UCP-1 in Mice Male ------ (RETRACTED) Chabib Fachry Albab; Purwo Sri Rejeki; Muhammad Miftahussurur; Soebagijo Adi Soelistijo
Health Notions Vol 3, No 12 (2019): December
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn31207

This article has been retracted at the request of the authors

CORRELATION BETWEEN KNOWLEDGE OF CITY OF RESIDENCE AND COVID19 IN SURABAYA YOUTH GENERATION Ricky Indra Alfaray; Lionardy Yodianto; Astri Dewayani; Kartika Afrida Fauzia; Dwiki Noni Armyta; Yudith Annisa Ayu Rezkitha; Reny I'tishom; Muhammad Miftahussurur
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 5 No. 1 (2021): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v5i1.2021.116-122

COVID19 pandemic became the primer focus of health problem by the government since the case was increasing every month in 2020. The impact of this pandemic was spread quickly across many areas including Surabaya city. Youth generation often found to be a silent source of infection. Furthermore, young people behavior often ignoring health prevention policy makes the infection more easily to spread. This condition might be because of their knowledge regarding COVID19 was relatively not enough. Factor that may affect their knowledge are varies including knowledge of city of residence. This study aims to evaluate the correlation between knowledge about city of residence with youth generation knowledge of COVID19 as this factor has not yet been studied before in Indonesia. We conducted an analytical cross-sectional with an online survey for youth generation across Surabaya to understand their knowledge concerning Surabaya and COVID19. A total of 57 participants were voluntarily enrolled in this study. The result data were analyzed statistically. There is significant positive correlation between participants’ knowledge of Surabaya city with knowledge of COVID19 (r= 0.314; p= 0.017). Furthermore, knowledge of COVID19 was significantly different between youth who have better knowledge of Surabaya than lower knowledge (p= 0.021). Knowledge of Surabaya city was correlated with knowledge of COVID19. Youth who have better knowledge regarding their city of residence seem to have better knowledge of COVID19. Knowledge concerning city of residence proven to be important in order to increase knowledge of COVID19 in youth generation.

RELATIONSHIP BETWEEN OBESITY, TWIN-PREGNANCY AND PREVIOUS HISTORY OF PREECLAMPSIA WITH PREECLAMPSIA Riani Widia Parantika; Gatut Hardianto; Muhammad Miftahussurur; Wahyul Anis
Indonesian Midwifery and Health Sciences Journal Vol. 5 No. 3 (2021): Indonesian Midwifery and Health Sciences Journal, July 2021
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v5i3.2021.307-316

Background: Preeclampsia can threaten the health of the mother and fetus during pregnancy and childbirth, besides that it also increases the risk of long-term complications and has the potential to cause death. The incidence of preeclampsia at the RSUD Engku Haji Daud Tanjung Uban showed an increase in the last three years, namely the occurrence from 2017 as many as 23 cases to 56 cases in 2019. The condition of preeclampsia can worsen quickly and without warning, for that, it must be detected and managed appropriately. This study aimed to identify the association of obesity, multiple pregnancies, and previous history of preeclampsia with the incidence of preeclampsia in maternity women. Methods: This study uses a case-control study design. Performed on women giving birth in the period January – December 2019, consisting of 56 cases and 112 controls. Maternal women with preeclampsia were cases and women who were not diagnosed with preeclampsia were controls. The data was obtained from the respondents' medical records, then analyzed using the Chi-Square test or Fisher's Exact test with a value of = 0,05. Results: Obesity was associated with an increased risk of preeclampsia (OR= 4,746, 95% CI 2,381-9,460; P=0,000). Multiple pregnancies were associated with a significantly increased risk of preeclampsia (OR=15,857, 95% CI 1,899-132,384; P=0,002). Likewise, a previous history of preeclampsia was associated with a markedly increased risk of preeclampsia (OR=99,000, 95% CI 22,057-444,343; P=0,000). Conclusion: Based on these data, it was found that obesity, multiple pregnancies, and previous history of preeclampsia were significant risk factors for the occurrence of preeclampsia. It is important to identify risk factors for preeclampsia early, so that appropriate management can be carried out, to prevent complications.

Quality of Life of Chronic Hepatitis B Patients Consuming Nucleoside Analog: A Case-Control Clinical Study in Indonesia Natasya Ariesta Selyardi Putri; R. Haryanto Aswin; Izzatul Fithriyah; Ummi Maimunah; Muhammad Miftahussurur; Yoshio Yamaoka
Biomolecular and Health Science Journal Vol. 5 No. 1 (2022): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v5i1.31409

Introduction: Chronic hepatitis B raises serious concern due to its high morbidity, such as cirrhosis and hepatocellular carcinoma, and mortality from 267 per 100,000 person-years. Up to now, medical therapy that successfully eradicates the hepatitis B virus is not available. Therapy is given in the long term for suppressing viral replication and disease progression. Nucleoside analog (NA) is a medication that is consumed orally once a day for years. Previous studies showed that patients who were treated with NA had a different quality of life (QoL) compared to naïve patients. This research aimed to analyze the QoL of chronic hepatitis B patients who consumed NA by comparing it with naïve patients at Dr. Soetomo General Academic Hospital Surabaya. Methods: Subjects were recruited consecutively from chronic hepatitis B patients at Dr. Soetomo General Academic Hospital Surabaya during 9 February – 31 May 2021. Data about sociodemographic characteristics, hepatitis B therapy history, and QoL were gained by using the SF-36 questionnaire and medical records. Subjects were divided into NA and naïve groups which responses underwent an analytical comparison. Results: NA group had significantly higher QoL in a physical component score (PCS) and mental component score (MCS), with physical functioning (PF), role limitations due to physical health (RP), role limitations due to emotional problems (RM), energy/fatigue (VT), emotional well-being (MH), social functioning (SF), and general health perception (GH) subscales having p<0.05Conclusion: The QoL of patients who were treated with NA was significantly higher than that of naïve patients in terms of physical and mental components.

Helicobacter pylori Antral Density More Valuable than Corporal Density in Chronic Gastritis Patients Bernadetta Jonan; Willy Sandhika; Ummi Maimunah; Muhammad Miftahussurur
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 20, No 2 (2019): VOLUME 20, NUMBER 2, August 2019
Publisher : The Indonesian Society for Digestive Endoscopy

Background: Helicobacter pylori has the capacity to colonize in stomach. In countries with a high prevalence of H. pylori, biopsy specimens must be obtained from corpus and antrum to elevate the accuracy. However, in a country with low prevalence of H. pylori such as Indonesia, the sensitivity of antrum specimen only is still questionable. We compared the density of H. pylori in the antrum and corpus of Indonesian gastric biopsy.Method: We conducted a prospective, cross-sectional, and observational study in thirty-two samples of corpus and antrum biopsy tissues from Pathology Anatomy Laboratory. The samples were stained by Modified Giemsa or Diff Quik. Updated Sydney System is utilized to classify the density of H. pylori.Results: Among 32 biopsy specimens from corpus and antrum, it has been statistically proven that H. pylori density in antrum and in corpus has a significant difference (65.5% vs. 15.6%, p 0.001). The density of H. pylori in antrum is mild predominant (43.8%), while the density in corpus is normal predominant (87.5%). Thus, the antral H. pylori infection was the predominant site. In 53.12% case, H. pylori was found in antrum but was not found in the corpus. In 6.24% case, H. pylori was found in both sites, but the density was higher in antrum. Importantly, no case with H. pylori infection in corpus only was found.Conclusion: H. pylori density in antrum is higher than in corpus. Only a small advantage to use additional biopsy from corpus to detect H. pylori in Indonesia.

Gastric Mucosa Plasma Cells is Unspecific for Diagnosing Helicobacter pylori Infection Gilda Hartecia; Willy Sandhika; Ummi Maimunah; Muhammad Miftahussurur
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 20, No 2 (2019): VOLUME 20, NUMBER 2, August 2019
Publisher : The Indonesian Society for Digestive Endoscopy

Background: A high density of Helicobacter pylori is believed to trigger an accumulation of plasma cells in the gastric mucosa. This accumulation stimulated the production of antibodies, causing high antibodies titer being circulated in the blood. The aims of this study is to identify the correlation between the number of plasma cells and H. pylori density in gastric mucosa.Method: This observational analytic study was performed with cross-sectional approach. The samples were the paraffin blocks which consisted of endoscopic gastric biopsy tissues of chronic gastritis patient in Anatomic Pathology Laboratory Dr. Soetomo General Hospital Surabaya in 2017 period. A total of 30 samples were purposively collected. Endoscopic gastric biopsy tissues were stained by two stains, Haematoxylin-Eosin and Modified Giemsa. The examination was performed by experienced pathologist. The correlation between total plasma cells and H. pylori density in gastric mucosa and the difference of total plasma cells between gastric mucosae with different density of H. pylori were determined.Results: There was no significant correlation between total plasma cells and H. pylori density in gastric mucosa. And there was no significant difference of the number of plasma cells found with different density of H. pylori.Conclusion: The number of plasma cells in the gastric mucosa is unspecific for diagnosing H. pylori infection. Other causes associated with plasma cells need to be assessed in further studies.

Clinical Outcome Controversy in Helicobacter pylori Infection Muhammad Miftahussurur; Heasty Oktaricha; Titong Sugihartono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 2 (2020): VOLUME 21, NUMBER 2, August 2020
Publisher : The Indonesian Society for Digestive Endoscopy

H. pylori infection can manifest as intestinal and extraintestinal disease. In this review, we summarize several factors that cause differences in clinical manifestations of H. pylori infection. Host inflammatory response and bacterial virulence are key in determining the pattern of acid secretion and gastritis. The acid level factor that has a greater effect, not H. pylori infection itself. Gastritis predominant in the gastric in the initial phase will produce higher acid and trigger GERD. H. pylori is also the cause of gastric adenocarcinoma. Different vacA genotypes are related to the risk of clinical manifestations such as peptic ulcer or gastric cancer. However, there is variance prevalence in some countries which can be explained through a combination of several factors including age at infection, virulence factors of H. pylori, host genetic profile, and environmental factors. Besides, important differences were found at a locus in CagA H. pylori which resulted in differences in clinical outcomes in the form of gastritis or MALT lymphoma. H. pylori infection alone is not enough to trigger idiopathic thrombocytopenic purpura (ITP). Additional triggers are needed to obtain an anti-platelet autoimmune response at ITP associated with H. pylori. Therefore, the difference in clinical manifestations of H. pylori infection remains controversial. H. pylori is not only a single cause, but the host and environmental factors also contribute to producing different responses.

FACTORS ASSOCIATED WITH ACUTE RESPIRATORY TRACT INFECTION PNEUMONIA IN TODDLERS Ayu Citra Gestari; Dwiyanti Puspitasari; Muhammad Miftahussurur
Indonesian Midwifery and Health Sciences Journal Vol. 6 No. 3 (2022): Indonesian Midwifery and Health Sciences Journal, July 2022
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v6i3.2022.274-283

Abstract Background: Most of the deaths of children under five in the world occur due to respiratory tract infections, especially in the lower respiratory tract. Pneumonia is one of the biggest causes of infant mortality in the world. Objective: The purpose of this study was to determine several factors that influence acute respiratory tract infections with pneumonia in children under five. Methods: Case control research design was used with statistical analysis of Chi Square test bivariate and multivariate logistic regression analysis which had a significance of 5%. Data collection using simple random sampling technique. Results: The variables that have the greatest significant value are immunization status and exclusive breastfeeding status. Toddlers with incomplete immunization have a 2.876-fold risk of being infected with pneumonia compared to toddlers who are fully immunized. Breastfeeding that is not exclusive is at risk of infection with pneumonia 3.111 times that of toddlers who are given exclusive breastfeeding. Conclusion: Exclusive breastfeeding status and immunization status are the most influential variables on acute respiratory tract infection with pneumonia. Keywords: pneumonia, exclusive breastfeeding, immunization

Co-Authors Adi Pranoto Adinda Juwita Syakila Elizafanti Agoes Soegianto Agus Sulistyono Alfaray, Ricky I. Alpha Fardah Athiyyah Alshawsh, Mohammed A. Amie Vidyani Ana, Devi Andino Maseleno Annisa Zahra Mufida Aryati -, Aryati Astri Dewayani Aswin, R. Haryanto Ayu Citra Gestari Bernadetta Jonan Brian Eka Rahman Budi Prasetyo Budi Widodo Chabib Fachry Albab Dewi, Selva R. Diah Rizki Rahma Dini Dianbudiyanto, Wahid Dita Mega Utami Djazuly Chalidyanto Dominicus Husada Dwiki Noni Armyta Dwiyanti Puspitasari, Dwiyanti Eka Mishbahatul Mar'ah Has Endyka Erye Frety Fauzia, Kartika A. Fauziah Diayu Retnaningtyas Gatut Hardianto, Gatut Gilda Hartecia Hadisuwarno, Wiharjo Hajjarianti, Permata Hamzah Hamzah Hartecia, Gilda Hasan Maulahela Heasty Oktaricha HERAWATI, LILIK Hermanto Tri Joewono Herry Purbayu Hertanto, Carisa Irene Hubur, Aa Hunowu, Ramdan I'tishom, Reny Indra Alfaray, Ricky Ishomatul Faizah Isna Mahmudah Isna Mahmudah Iswan A Nusi Iswan Abbas Nusi Izzatul Fithriyah Jonan, Bernadetta Juniastuti Juniastuti Karnaji, Karnaji Kartika Afrida Fauzia Lionardy Yodianto Mahmudah, Isna Maria Inge Lusida Martono Tri Utomo MISBAKHUL MUNIR Mohammad Anam Al-Ari Nadia Sherli Syafira Natasya Ariesta Selyardi Putri Naufali Rizkiawan Nihayati, Hanik Endang Nurhayati, Fitasari Nidia NUrina Fitriani, NUrina Nurullia Hanum Hilfida Pangestu Adi Pathak, Yashwant Poernomo Boedi Setiawan Purwo Sri Rejek Rejeki, Purwo Sri Riani Widia Parantika Rizkiawan, Naufali Samsriyaningsih Handayani Savitri, Camilia Metadea Aji Soelistijo, Soebagijo Adi Sugiyatmi, Tri A. Sulistiawati Sulistiawati Susanti Susanti Tanaya, Willa M. Thamrin, Husin Titong Sugiharto Titong Sugihartono Tri Purwanti Ucik Nurul Hidayati Ulfa Kholili Ummi Maimunah Usman Hadi Vasa Adi Wisnu Wardana Wahyul Anis Watari, Rekno Wati, Yunita Kholilaili Saras Wessels, Firda I. Widjiati Widjiati Widyaleksono, Trisnadi Willy Sandhika Woro Setia Ningtyas Yoshio Yamaoka Yoshio Yamaoka Yoshio Yamaoka, Yoshio Yudith Annisa Ayu Rezkitha Yudith Annisa Ayu Rezkitha, Yudith Annisa Ayu Zagita, Lauditta Chavia

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