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All Journal Konfrontasi: Jurnal Kultural, Ekonomi dan Perubahan Sosial Britain International of Humanities and Social Sciences (BIoHS) Journal Britain International of Exact Sciences Journal (BIoEx Journal)
Robijaona Rahelivololoniaina Baholy
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Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Environmental Science Mathematics Medicine & Pharmacology Physics Social Sciences

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Phytochemical Analysis of Cynometra Madagascariensis (Fabaceae), a Malagasy Medicinal Plant Andrianarijaona Mamy; Ralaivaon-Dratsitonta Jumaël Edith Fabrice; Fatiany Pierre Ruphin; Robijaona Rahelivololoniaina Baholy
Britain International of Exact Sciences (BIoEx) Journal Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v7i3.1361

Abstract

A comprehensive phytochemical and physicochemical investigation was conducted on the bark of Cynometra madagascariensis, a plant of the Fabaceae family traditionally used in Madagascar to treat and heal wounds and burns. Sequential maceration extractions were performed with solvents of increasing polarity (hexane, dichloromethane, and methanol) to obtain a range of crude extracts. Subsequent phytochemical screening revealed a diverse chemical profile, with a significant presence of tannins and terpenoids, and lower concentrations of quinones and saponins. Alkaloids, coumarins, flavonoids, and steroids were notably absent from the bark. Chromatographic methods were then employed for the separation and isolation of constituents from the hexane extract. Thin-layer chromatography (TLC) was utilized to optimize the mobile phase and monitor the fractionation process. This led to the successful isolation of a pure compound, designated F58-60, through column chromatography. The structure of this molecule was elucidated using one-dimensional NMR spectroscopy (1H and 13C NMR). A comparative analysis of the spectroscopic data with published literature confirmed the compound's identity as di(2-ethylhexyl) phthalate. This research provides a foundational understanding of the chemical composition of this medicinal plant and paves the way for further studies on the biological activities of its constituents.
Unveiling the Bio-Inspired and Green Chemistry Potential of Ceylon and Cape Gooseberries through Comprehensive Nutritional Profiling Razafimahefa Mirana Verohanitra; Razafindrazanakolona, Daniel; Ralaivaon-Tsitonta Jumael Edith Fabrice; Robijaona Rahelivololoniaina Baholy
Britain International of Exact Sciences (BIoEx) Journal Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v7i3.1362

Abstract

This study meticulously investigates the chemical and nutritional profiles of two underexplored tropical fruit species indigenous to Madagascar: the Ceylon Gooseberry (Dovyalis hebecarpa) and the Cape Gooseberry (Physalis peruviana). Characterizing such native species is vital for diversifying food sources and enhancing nutritional security, particularly in biodiversity-rich regions.Systematic analyses performed across various plant compartments, notably their foliage, revealed a significant richness in essential micronutrients. Leaves of both species demonstrated substantial concentrations of potassium, phosphorus, iron, magnesium, and aluminum. Furthermore, Physalis peruviana leaves exhibited a particularly significant protein content, elevating their prospective utility beyond fruit consumption. This robust nutritional profile reinforces their potential as valuable, locally sourced ingredients to foster balanced diets in the region. Parallel to the nutritional assessment, empirical processing trials were initiated to ascertain the technological feasibility and quality attributes of derived products, focusing on wine. The fermentation processes consistently yielded wines categorized as dessert wines, which demonstrated stable physicochemical characteristics and promising shelf-life properties. This intrinsic stability, coupled with their unique profiles, suggests compelling added value within agro-food valorization strategies. Collectively, these findings underscore the considerable potential of both Dovyalis hebecarpa and Physalis peruviana for the innovative development of novel food products. Such initiatives not only contribute to agricultural diversification but also align seamlessly with circular economy principles by utilizing underexploited plant parts, and sustainable development by fostering local biodiversity and resource efficiency. This research provides a scientific basis for promoting the cultivation and processing of these indigenous fruits, contributing to economic growth and environmental stewardship.
Phytochemical Analysis and Therapeutic Interests of Azadirchta Indica (Meliaceae) Andrianarijaona Mamy; Ralaivaon-Dratsitonta Jumaël Edith Fabrice; Fatiany Pierre Ruphin; Robijaona Rahelivololoniaina Baholy
Britain International of Exact Sciences (BIoEx) Journal Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v7i3.1364

Abstract

This study presents a phytochemical and structural investigation of Azadirachta indica, a plant widely used in traditional medicine in Madagascar for ailments such as malaria and fever. A systematic solid-liquid extraction of the plant's bark, employing solvents of increasing polarity, yielded various crude extracts. Subsequent phytochemical screening confirmed the abundance of key secondary metabolites, including alkaloids, tannins, polysaccharides, and saponins. The dichloromethane extract, having the highest yield, was selected for further analysis. A compound was successfully isolated from this extract using thin-layer chromatography (TLC) and preparative column chromatography. Its structure was then elucidated using a combination of one-dimensional spectroscopic techniques, including Electron Ionization Mass Spectrometry (EI-MS), 1H Nuclear Magnetic Resonance (NMR), and 13C NMR (with DEPT-135). The analysis of the spectral data, combined with a comprehensive literature review, led to the identification of the isolated molecule as 2-oxo-1,2-dihydroquinoline-4-carboxylic acid, an alkaloid with the molecular formula C10H7NO3. This compound is characterized by a two-ring system and six degrees of unsaturation, consistent with its spectral data. This research not only validates the traditional use of the plant but also provides a foundation for future pharmacological studies on this isolated compound.
Enhancing the Value of Sweet Potatoes in Madagascar: Between Food Security and Productive Capital – A Socio-Anthropological Approach Ramangarijaona Simon Ludovic; Raherimalala Etienne Stefano; Ravelo Bruno Eugène Maxime; Rakotorahalahy Njaka Herihajatsilaozana Elisabeth; Ravelonjatovo Haja Herilala; Andrianjary Myriam; Ratiarimananjatovo Narindra; Robijaona Rahelivololoniaina Baholy
Britain International of Exact Sciences (BIoEx) Journal Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v7i3.1365

Abstract

This study focuses on the valorization of sweet potatoes in Madagascar from the perspective of food security and the accumulation of productive capital, as defined by Nurkse—that is, through the establishment of basic infrastructure. The research was conducted in the geographic areas of Ankazobe, in the northern highlands, as well as in Tsarasaotra in the Amoron'i Mania region, and in Soaindrana and Talata Ampano in the Matsiatra Ambony region. These areas are distinguished by their diverse sociocultural and economic characteristics. The central question is whether it is reasonable to consider development based on a modest, indigenous yet widespread resource like the sweet potato. The findings indicate that if its production were to increase, following a shift in the devaluing perceptions commonly associated with it, this would lead to strengthened food security. Furthermore, if basic innovations—both technical and organizational—are adopted in rural settings, the production of this tuber crop could promote the rapid accumulation of productive capital, a key element in any development process. Drawing on De Sardan’s framework of entangled social logics, which emphasizes changes in mentality, the concept of agency, and Weber’s ideal-type vision of capitalism, the objective is to move away from grand macroeconomic development theories and adopt a pragmatic approach centered on local potential. Development must therefore be rethought as a cultural process, grounded in representations and enculturated behaviors (habitus, hexis), by establishing a link between increased production and rural mentalities. The study also shows that ongoing innovations in production methods—such as those related to sweet potatoes—do not necessarily need to be expensive to trigger mechanisms for the formation of productive capital.
Phytochemical analysis of Leptadenia madagascariensis Decne (Apocynaceae) Andrianarijaona Mamy; Ralaivaon-dratsitonta Jumaël Edith Fabrice; Fatiany Pierre Ruphin; Robijaona Rahelivololoniaina Baholy
Britain International of Exact Sciences (BIoEx) Journal Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v7i3.1368

Abstract

Leptadenia madagascariensis Decne, a woody climbing vine endemic to Madagascar, has long been utilized in traditional medicine for its therapeutic properties, despite a lack of detailed scientific investigation. This study was conducted to perform a comprehensive phytochemical analysis of the plant’s aerial parts, thereby contributing to the chemical validation of its ethnobotanical applications and supporting national conservation efforts. The powdered plant material was successively macerated with hexane, dichloromethane (DCM), and methanol, yielding crude extracts with varying polarity. Phytochemical screening of these extracts revealed a significant concentration of polysaccharides, saponins, and steroids. The DCM extract, showing a promising phytochemical profile, was selected for further purification. An initial analysis by thin-layer chromatography (TLC) indicated the presence of four dominant compounds. Subsequent separation using column chromatography resulted in the isolation of a pure compound from fractions 55 to 70. The structure of this isolated compound was determined through a combination of spectroscopic techniques, including mass spectrometry and one-dimensional nuclear magnetic resonance (NMR) spectroscopy (1H NMR, 13C NMR, and DEPT). The spectral data were compared with literature values, leading to the definitive identification of the molecule as β-Sitosterol, a common tetracyclic steroid. This finding confirms the presence of therapeutically valuable steroid compounds in L. madagascariensis, providing a scientific basis for its traditional use and a starting point for further pharmacological research.
The Sacred Matrix: Reclaiming the Feminine Body as Ontological Vocation in Hebrew and Malagasy Cosmologies Rafaramalala Dyna; Robijaona Rahelivololoniaina Baholy
Konfrontasi: Jurnal Kultural, Ekonomi dan Perubahan Sosial Vol 12 No 3 (2025): Konfrontasi, September
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/konfrontasi2.v12i3.341

Abstract

This theological reflection embarks on a profound comparative exegesis, plumbing the depths of the female body's symbolic resonance within two disparate yet remarkably convergent sacred traditions: ancient Hebrew biblical anthropology and the Malagasy cosmovision. Employing a rigorous interdisciplinary methodology that weaves together exegesis, symbolic anthropology, linguistics, and contextual theology, this study illuminates how both traditions imbue the feminine form with rich layers of sacred, ontological, and relational meaning. Central to this exploration is the Hebrew term neqēvāh (נְקֵבָה), commonly rendered "woman." Far from a mere biological descriptor, neqēvāh is here unpacked as a potent theological metaphor — a signifier of ontological openness, spiritual receptivity, and sacred fecundity. This understanding is then brought into a generative dialogue with evocative Malagasy expressions such as mitondra rano ("water bearer"), trano zaza ("child’s house"), and tratra masoandro ("touched by the sun"). Strikingly, these seemingly disparate metaphors converge towards a unified theological apprehension of femininity not as a state of biological passivity, but as a dynamic, vivifying space of creation, transmission, and cosmic mediation. This inter-epistemic approach not only unveils the profound richness inherent in localized sacred traditions but also underscores the urgent theological imperative to revalorize the female figure within contemporary theological discourses. It invites us to perceive the feminine body as a locus of divine immanence and a conduit for cosmic flourishing.
Co-Authors Andrianarijaona Mamy Andrianarimanana Jean Claude Omer Andrianarivony Tiona Andrianiaina Solo Raivo Lyh Raphaël Andrianjafy Philippe Patrick Andrianjary Myriam Andriazafinahazo Fridolin Etienne Stefano Raherimalala Fatiany Pierre Ruphin Fidelio Arnold Fidelio Arnold Ulrich Henri, Ratojoarivelo Setriniaina Herimanantena Miarantsoa Tinah Koto-te-Nyiwa Ngbolua Letsara Rokiman Rabarison Rindra Rabeharitsara Andry Tahina Rabotovao Sebas David Rafaramalala Dyna Rahajamanana Jasmin Rahanetra Dina Raherimalala Etienne Stefano Rajaonah Rabevala Rakotomalala Iarivontsoa Nekena Sahaza Rakotomalala Nivomboahangy Razanamiarisoa Rakotomamonjy Pierre Rakotorahalahy Njaka Herihajatsilaozana Elisabeth Rakotoson Olivia Ralaibia Boniface Erménégilde Ralaivaon-dratsitonta Jumaël Edith Fabrice Ralaivaon-Tsitonta Jumael Edith Fabrice Ramangarijaona Simon Ludovic Ramarolahy Patricia Josette Ramasinoro Naly Ramiadamahefa Tojoniaina Ranjatson Jean Patrick Rasoloarivony Theis Lala Ratiarimanajatovo Narindra Ratiarimananjatovo Narindra Ratojoarivelo Setriniaina Henri Ratsimandisa Haritiana Zo Ratsimbazafy Ratsimbazafy Aro Pascal Ravelo Bruno Eugène Maxime Ravelomanantsoa Ramanambe Nicole Ravelonjatovo Haja Herilala Razafimahefa Mirana Verohanitra Razafindrakoto Fanoina Ny Riana Razafindrazanakolona Andrianjafimanjato Daniel Razafindrazanakolona Daniel Razafindrazanakolona, Daniel Razakatiana Andriamampitasoa Daniel José Razanadrasoa Vololonome Bodomalala Razanamparany Bruno Rejo Robert Rindra, Rabarison Sahala, Rakotomalalaridio Antsa Sigrid Aubert Solofomiarana Rapanoel Bruno Allain Tsimiondrike Mahasoa