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All Journal Indonesian Nursing Journal of Education and Clinic (Jurnal Pendidikan dan Praktik Keperawatan Indonesia) Jurnal Farmasi SYIFA
Crisdian S, Hanugrah Ardya
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Nursing Public Health

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THE EFFECTIVENESS OF GALENIC CREAM OF DURIAN PEEL EXTRACT AND CHITOSAN FOR TREATMENT OF DIABETIC ULCERS Agustin, Wahyu Rima; Harti, Agnes Sri; Crisdian S, Hanugrah Ardya; Saputro, Sutiyo Dani; Saelan, Saelan
INDONESIAN NURSING JOURNAL OF EDUCATION AND CLINIC (INJEC) Vol 8, No 2 (2023): INJEC
Publisher : Asosiasi Institusi Pendidikan Ners Indonesia (AIPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24990/injec.v8i2.597

Abstract

Introduction: The chemical substance of durian peel (Durio zibethinus L.) is a polysaccharide polymer of D-galacturonic acid which is polar and anti-microbial. Chitosan is a derivative of chitin from the peels of Crustaceae animals, which is polycationic and antimicrobial; biodegradable, and biocompatible wit animal tissues. Diabetic ulcers are chronic wounds due to neurological disorders and vascular disorder in the legs, causing tissue damage. The purpose of the study was to analyze the effectiveness of galeni preparations of durian peel extract and chitosan for the treatment of diabetic ulcers.Method: This research is experimental including testing the quality of 5% durian peel extract cream preparations; 2% chitosan, a mixture of both ratio = 1:1; 1:2 physically, chemically, and microbiologically,and the rate of wound healing in test animals. Statistical data analysis of One Way Anova parametric test.Results: The results showed that the preparation of galenic durian peel extract cream and chitosan and their combination ratio (1:1), (1:2) could be formulated and met the quality test of cream preparations physically, chemically, and microbiologically according to the requirements of BPOM No. 32 of 2019 and is effective for healing diabetic ulcers on the 8th day.Conclusions: The preparation of galenic durian peel extract cream and chitosan and their combination ratio (1:1), (1:2) can potentially be developed as a cream preparation for healing diabetic ulcers.
Analisis Dengan Metode ABC Pada Tahap Pengendalian Obat Antibiotik di Instalasi Farmasi RSUD Ibu Fatmawati Soekarno Surakarta Periode Tahun 2024 Crisdian S, Hanugrah Ardya; Luthfiananda, Berliana; Sari, Agnes Prawistya; Chatrine, Elizabet Davira
Jurnal Farmasi SYIFA Vol 4 No 1 (2026): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jfs.v4i1.963

Abstract

Pengendalian obat adalah salah satu tahapan dalam pelayanan kefarmasian yang dilakukan terhadap jenis dan jumlah persediaan dan penggunaan sediaan farmasi, Pengendalian obat dilakukan oleh Instalasi Farmasi bersama dengan Komite Farmasi dan Terapi di Rumah Sakit yang bertujuan untuk memastikan persediaan efektif dan efisien atau tidak terjadi kelebihan, kekurangan, kekosongan ataupun kadaluwarsa. Antibiotik digunakan untuk mencegah dan mengobati penyakit-penyakit infeksi. Antibiotik merupakan salah satu obat dimana pemakaiannya cukup tinggi dan menggunakan alokasi dana yang besar. Tujuan penelitian ini Untuk mengetahui analisis ABC pada pengendalian obat antibiotik di Instalasi Farmasi RSUD Ibu Fatmawati Soekarno Surakarta. Penelitian ini dilakukan dengan metode deskriptif analitik kohort menggunakan pendekatan kuantitatif. Rancangan penelitian menggunakan data retrospektif. Data yang diperoleh selanjutnya dilakukan analisis data menggunakan excel. Dari hasil penelitian, analisis metode ABC pada obat antibiotik kategori A terdapat 6 item obat (10,2%) dengan nilai investasi Rp 2.860.029.816,00 (78,1%), kategori B terdapat 11 item obat (18,6%) dengan nilai investasi Rp 615.854.428,00 (16,8%), dan kategori C terdapat 42 item obat (71,2%) dengan nilai investasi Rp 186.236.883,00 (5,1%).
Co-Authors Agnes Sri Harti Chatrine, Elizabet Davira Luthfiananda, Berliana Saelan, Saelan Saputro, Sutiyo Dani Sari, Agnes Prawistya Wahyu Rima Agustin