Article Per Year (5 Year)
p-Index From 2020 - 2025
1.633
P-Index
This Author published in this journals
All Journal Indonesian Journal of Medicine Jurnal Biomedika Jurnal Peduli Masyarakat International Journal of Public Health Excellence (IJPHE) Indonesian Nursing Journal of Education and Clinic (Jurnal Pendidikan dan Praktik Keperawatan Indonesia) Jurnal Masyarakat Madani Indonesia Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan
Agnes Sri Harti
Jurusan D-III Keperawatan STIKes Kusuma Husada Surakarta
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 10 Documents
Search

 1 
THE EFFECTIVENESS OF GALENIC CREAM OF DURIAN PEEL EXTRACT AND CHITOSAN FOR TREATMENT OF DIABETIC ULCERS Agustin, Wahyu Rima; Harti, Agnes Sri; Crisdian S, Hanugrah Ardya; Saputro, Sutiyo Dani; Saelan, Saelan
INDONESIAN NURSING JOURNAL OF EDUCATION AND CLINIC (INJEC) Vol 8, No 2 (2023): INJEC
Publisher : Asosiasi Institusi Pendidikan Ners Indonesia (AIPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24990/injec.v8i2.597

Abstract

Introduction: The chemical substance of durian peel (Durio zibethinus L.) is a polysaccharide polymer of D-galacturonic acid which is polar and anti-microbial. Chitosan is a derivative of chitin from the peels of Crustaceae animals, which is polycationic and antimicrobial; biodegradable, and biocompatible wit animal tissues. Diabetic ulcers are chronic wounds due to neurological disorders and vascular disorder in the legs, causing tissue damage. The purpose of the study was to analyze the effectiveness of galeni preparations of durian peel extract and chitosan for the treatment of diabetic ulcers.Method: This research is experimental including testing the quality of 5% durian peel extract cream preparations; 2% chitosan, a mixture of both ratio = 1:1; 1:2 physically, chemically, and microbiologically,and the rate of wound healing in test animals. Statistical data analysis of One Way Anova parametric test.Results: The results showed that the preparation of galenic durian peel extract cream and chitosan and their combination ratio (1:1), (1:2) could be formulated and met the quality test of cream preparations physically, chemically, and microbiologically according to the requirements of BPOM No. 32 of 2019 and is effective for healing diabetic ulcers on the 8th day.Conclusions: The preparation of galenic durian peel extract cream and chitosan and their combination ratio (1:1), (1:2) can potentially be developed as a cream preparation for healing diabetic ulcers.
The Effectiveness of Anti-Inflammatory Cream Galenic Preparations Based on Snail Seromucoid, Durian Peel Extract Polysaccharides and Chitosan in the Wound Healing Process (In Vivo) Harti, Agnes Sri; Sutanto, Yusup Subagio; Agustin, Wahyu Rima; Putriningrum, Rahajeng; Irdianty, Mellia Silvy; Saelan, Saelan; Ardiani, Nurul Devi
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 2 (2024): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i2.876

Abstract

Development of galenic preparation formulations that can be used to make anti-inflammatory cream preparations. Snail seromucoid contains glycoproteins, mannose carbohydrates, glucose, N-acetyl muramic acid and the α-1 globulin-oromucoid fraction which functions as a bioimmunostimulator. Durian peel (Durio zibethinus L.) contains a polar polysaccharide polymer compound such as D-galacturonic acid which has anti-microbial properties. Chitosan is a polymer compound resulting from derivatization of chitin which has antimicrobial polycationic properties; biodegradable, and biocompatible with animal body tissue. The aim of the research was to examine the effectiveness of a galenic anti-inflammatory cream preparation based on snail seromucoid, durian skin extract, and chitosan for healing acute and chronic wounds in vivo. The research method is experimental research, namely the effectiveness of anti-inflammatory galenic cream preparations made from snail seromucoid, durian peel extract and chitosan on various types of wounds in vivo. Analysis of observation data using the one way anova test. A galenic preparation based on a combination of 2% snail seromucoid, 2% durian peel extract polysaccharide and 2% chitosan ratio 1:1:1 is effective in the healing process based on the formation of granulation tissue thickness in incision injuries, hot objects injuries, second degree burns and ulcers. diabetes. The bioformulation galenic preparation of 2% snail seromucoid, 2% polysaccharide of durian peel extract; 2% chitosan and their combination with ratio 1:1:1 is effective as an anti-inflammatory galenic cream preparation so that it can be applied for healing chronic wounds, acute wounds and diabetic ulcers.
The Potential and Effectiveness of Snail Seromucoid and Chitosan as Bioimmunostimulators Harti, Agnes Sri; Sutanto, Yusup Subagio; Puspawati, Nony
Biomedika Vol 15 No 2 (2022): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/biomedika.v15i2.1448

Abstract

The host's cellular immune response plays an important role in the process of eliminating microorganisms that cause infection. Substances that can stimulate an increase in the immune response are called immunostimulators. Snail seromucoid contains bioactive compounds such as glycans, peptides, glycopeptides and chondroitin sulfate. Chitosan as an antimicrobial agent can be used in the biomedical field because chitosan has a number of hydroxyl groups (OH) and amine groups (NH2). The research objective was to determine the potency and effectiveness of snail seromucoid and chitosan as bioimmunostimulators. The research method is based on laboratory experimental results with the research stages, namely the analysis of the effectiveness of seromucoid and chitosan on lymphocyte proliferation. The results of the one way ANOVA analysis showed a p value of 0.000 so that there was a significant effect between the treatment groups, namely the effect of giving chitosan 65 ug/ml; snail mucus 65 ug/mL and a combination of chitosan (65 ug/mL) and snail mucus (65 ug/mL) ratio of 1:1, can increase lymphocyte proliferation optimally. This shows that snail mucus, chitosan and their combination in a 1:1 ratio are effective as BRM (Biological Response Modifier). It is hoped that the contribution of the results of this study can be further developed in the bioformulation of snail seromucoid preparations and chitosan as therapeutic agents for infectious diseases, including Acute Respiratory Distress Syndrome (ARDS), Tuberculosis and other diseases.
Program Pemberdayaan UMKM Pemanfaatan Ampas Gula Jahe menjadi Produk Pangan Krenova Saelan, Saelan; Harti, Agnes Sri; Surya, Nella Tri; Kusumawati, Dewi
Jurnal Peduli Masyarakat Vol 6 No 4 (2024): Jurnal Peduli Masyarakat: Desember 2024
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jpm.v6i4.4195

Abstract

Pemanfaatan ampas jahe dari limbah pembuatan gula jahe dapat dimanfaatkan menjadi produk Krenova, salah satunya adalah kue eggroll. Kegiatan ini dilaksanakan di Posyandu Anggrek Desa Wonorejo Kecamatan Gondangrejo Kabupaten Karanganyar. Di Posyandu Anggrek wonorejo ada beberapa Kader dan masyarakat yang kurang produktif secara ekonomi sehingga kegiatan ini diharapkan untuk membantu meningkatkan perekonomian mereka. Dengan memanfaatkan limbah ampas jahe dari pembuatan Gula Jahe yang salah satu bahan dasarnya yang berupa jahe, menyebabkan produksi gula jahe ini menghasilkan limbah yang berupa ampas jahe. Ampas jahe merupakan limbah industri jamu maupun minuman kesehatan ataupun jahe instan. Tujuan pengabdian kepada Masyarakat ini adalah pemberdayaan kader dan Masyarakat melalui kegiatan pembuatan kue eggroll dari pemanfaatn ampas gula jahe, kegiatan dilaksanakan selama 2 hari yaitu 16-17 Agustus 2024 yang diikuti oleh 15 orang yang terdiri dari 8 kader posyandu anggrek dan 7 masyarakat desa Wonorejo. Metode yang digunakan adalah demonstrasi pembuatan eggroll. Hasil dari demonstrasi pembuatan eggroll didapatkan hasil kegiatan bahwa kader Posyandu Anggrek dan Masyarakat mengetahui cara pembuatan eggroll.
Synbiotic Soygurt Tempe Extract as A Functional Beverage Harti, Agnes Sri; Irdianty, Mellia Silvy; Muhlishoh, Arwin; Sutanto, Yusup Subagio
International Journal of Public Health Excellence (IJPHE) Vol. 4 No. 1 (2024): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v4i1.1124

Abstract

Synbiotic tempeh extract soyghurt is a Krenova (creative and innovative) food product because it is novelty and unique as healthy and safe food, functional food, fun for diet and one for all. The result of probiotic fermentation of Lactic Acid Bacteria (LAB) and based on synbiotic tempeh extract (rice bran and chitosan) which has multifunctional anti-hyperglycemia and anti-hypercholesterolemia properties. Research objective: to analyze the effectiveness of synbiotic tempeh soyghurt as a functional drink. The research method analyzes the nutritional content and quality of synbiotic tempeh soygurt products which refer to SNI 7552:2009 concerning flavored fermented milk. Data analysis used bivariate and multivariate Anova tests. The Hedonic test results showed a semi-solid texture, white color, synbiotic tempeh extract aroma, sour taste in the formulation with the addition of 15% skim milk, 1% chitosan, 1:1 ratio LAB starter mix and 5% inoculum. The results of physical chemical and mycobiological quality tests show that the synbiotic tempeh extract meets the quality test as a functional drink.
Hilirisasi Produk Krenova Krim Galenik untuk Perawatan Luka bagi Praktisi Kesehatan Harti, Agnes Sri; Sutanto, Yusup Subagio; Agustin, Wahyu Rima; Irdianty, Mellia Silvy; Saelan, Saelan
Jurnal Peduli Masyarakat Vol 6 No 4 (2024): Jurnal Peduli Masyarakat: Desember 2024
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jpm.v6i4.4425

Abstract

Penerapan hasil riset civitas akademika Universitas Kusuma Husada Surakarta terkait eksplorasi potensi bahan alam dan pengembangan teknologi formulasi sediaan farmasi berbasis bahan galenik bioimunostimulator perlu dioptimalkan untuk menunjang efektivitas terapi perawatan luka kronis. Tujuan kegiatan sesuai paradigma kegiatan pengabdian pada masyarakat melalui fasilitasi Program Inovokasi Universitas Kusuma Husada Surakarta tahun 2024 adalah diseminasi dan implementasi sediaan galenik sebagai produk krenova berbasis knowledge based economy yang siap dihilirisasi dan dikomersialisasi secara profesional; mandiri serta berkelanjutan. Metode kegiatan meliputi transfer knowledge workshop manajemen perawatan luka manajement perawatan luka kepada 30 orang praktisi atau perawat mandiri dan webinar kolaborasi internasional antara Universitas Kusuma Husada Surakarta dan Instituto Ciencias Da Saude (ICS) Timor Leste tentang kuliah pakar manajemen perawatan luka antara yang diikuti oleh 325 peserta aktif secara online. Diseminasi dan implementasi produk krenova civitas akademika UKH Surakarta sediaan galenik seromukoid bekicot, ekstrak kulit durian dan atau kitosan sebagai healthy and safety product untuk wound healing melalui kolaborasi link and match antara UKH Surakarta dengan mitra industry herbal, bidang layanan kesehatan yaitu praktisi mandiri, home care, ataupun unit layanan kesehatan lain guna mendukung tercapainya hilirisasi produk krenova krim galenik antiinflamasi dan mendukung suksesnya program Pemerintah dalam penanggulangan perawatan luka kronis di Indonesia.
Diseminasi Produk Krenova Krim Galenik Anti Inflamasi melalui Program Kemitraan Masyarakat Agustin, Wahyu Rima; Harti, Agnes Sri; Sutanto, Yusup Subagio; Safitri, Wahyuningsih; Saelan, Saelan
Jurnal Peduli Masyarakat Vol 6 No 4 (2024): Jurnal Peduli Masyarakat: Desember 2024
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jpm.v6i4.4426

Abstract

Prototipe sediaan krim galenik ekstrak kulit durian dan kitosan sebagai produk kesehatan krenova berbasis senyawa bioaktif alami anti inflamasi yang efektif, aman, halal dan ekonomis untuk perawatan luka kronis; berwawasan knowledge based economy, product safety dan product hygiene yang siap dihilirisasi dan dikomersialisasi secara professional, mandiri, berkelanjutan. Tingginya kasus luka kronis disebabkan paradigma yang masih ada di masyarakat maka tujuan kegiatan pengabdian masyarakat yaitu pendidikan kesehatan bagi masyarakat dan diseminasi produk krenova krim galenic anti inflamasi melalui program kemitraan masyarakat. Pelaksanaan kegiatan PKM UKH Surakarta melibatkan tim pelaksana yaitu 10 dosen dan 12 mahasiswa bersama 9 kader serta 30 orang masyarakat Posyandu Cempaka Desa Wonorejo, Gondangrejo Kabupaten Karanganyar yang mendapat respon dan antusias dari masyarakat melalui peran serta dan keterlibatan aktif sesi diskusi dan tanya jawab. Diseminasi produk krenova sediaan galenic anti inflamasi untuk perawatan luka yang dilakukan secara berkelanjutan, tuntas dan bermakna melalui program kemitraan masyarakat mendukung tercapainya target hilirisasi produk kesehatan kreova yang bermanfaat bagi masyarakat guna mendukung permasalahan terapi luka kronis khususnya Posyandu Cempaka Desa Wonorejo, Kec. Gondangrejo, Kabupaten Karanganyar.
The Impact of the COVID-19 Pandemic on the Resistance Level of Mycobacterium Tuberculosis in Suspected Tuberculosis Patients at the Surakarta Central General Hospital Sutanto, Yusup Subagio; Sutanto, Magdalena; Harti, Agnes Sri
Indonesian Journal of Medicine Vol. 7 No. 1 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Analysis of the impact of the Covid-19 pandemic on the resistance level of Mycobacterium tuberculosis (MTb) isolates to Anti Tuberculosis Drugs (ATD) needs to be carried out considering the level of MTB resistance is an important factor in the occurrence of Multidrug-Resistant TB (MDR-TB) in Indonesia. The purpose of the study was to analyze the impact of the Covid-19 pandemic on the level of resistance of MTb isolates of patients with suspected TB in Surakarta.Subjects and Method: This research is a quantitative descriptive study with a retrospective Cohort based on the medical record data of suspected TB patients  at Surakarta Central General Hospital in 2020 – 2021. The sampling technique was random sampling with a total of 200 samples each year. Data analysis used the SPSS 21 program.Results: Characteristics of respondents with suspected TB patients who visited the Surakarta Central General Hospital in 2020 and 2021, mostly in men and occurring in productive ages 36-55 years. The most effective type of ATD against MTb isolates is Rifampicin with a mean rank of 6.00 and a p=0.035. While Ethambutol is ineffective as an ATD with a mean rank of 58.00 and a p<0.001. The results of the Wilcoxon test analysis showed  there was a significant difference in the level of resistance or sensitivity of MTb isolates in 2020 and 2021 with a p-value=0.000.Conclusion: There is a significant effect of the impact of the Covid-19 pandemic on the level of resistance or sensitivity of MTb isolates of patients with suspected TB in the Surakarta area in 2020 and 2021.Keywords: pandemic, Covid-19, resistance, MTb isolates, ATDCorrespondence: Yusup Subagio Sutanto. Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: yusupsubagiosutanto@gmail.com. Mobile: +62811284165.Indonesian Journal of Medicine (2022), 07(01): 28-38https://doi.org/10.26911/theijmed.2022.07.01.04
Edukasi Kesehatan dan Implementasi Produk Krenova Krim Galenik Untuk Perawatan Luka Melalui Optimalisasi Pemberdayaan Kemitraan Masyarakat Harti, Agnes Sri; Syukur, Bambang Abdul; Sutanto, Yusup Subagio; Puspawati, Nony
Jurnal Masyarakat Madani Indonesia Vol. 4 No. 3 (2025): Agustus
Publisher : Alesha Media Digital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59025/5m5ga075

Abstract

Penerapan hasil riset civitas akademika Universitas Kusuma Husada Surakarta terkait eksplorasi potensi bahan alam dan pengembangn teknologi formulasi sediaan galenik berbasis bahan alam perlu dioptimalkan untuk menunjang efektivitas terapi perawatan luka. Produk krenova krim galenik untuk perawatan luka berbasi seromukoid bekicot 1%, ekstrak kulit durian 1% dan kitosan 1%, telah terdaftar Paten Sederhana No. S00202214385 dan No. S00202010479. Tingginya kasus luka kronis disebabkan paradigma yang masih ada di masyarakat khususnya di Posyandu RW 16 Ceplukan, Desa Wonorejo, memberikan gambaran perlunya dilakukan edukasi kesehatan bagi masyarakat terkait permasalahan perawatan luka. Tujuan kegiatan melakukan edukasi kesehatan dan implementasi produk krenova untuk perawatan luka berbasis knowledge based economy, healthy and safety product melalui optimalisasi pemberdayaan kemitraan masyarakat. Metode pelaksanaan berupa edukasi kesehatan menggunakan leaflet, diskusi dan tanya jawab serta evaluasi kegiatan melalui pre dan post kuisioner tentang perawatan luka terhadap 30 peserta. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan terhadap materi manajemen perawatan luka yaitu peserta memiliki pengetahuan baik pre test 5 peserta (16,7%) dan post test 21 peserta (70). Implementasi esensi dan kebermanfaatan hasil riset yaitu terjalinnya kolaborasi kemitraan link and match dengan stake holder, DUDI dan masyarakat guna mendukung suksesnya program Pemerintah untuk menunjang efektivitas terapi perawatan luka kronis.
The Dissemination of Synbiotic Tempe Extract Krenova Soygurt Products as Functional Drinks for Stunting Prevention through Community Partnership Programs Harti, Agnes Sri; Irdianty, Mellia Silvy; Ardiani, Nurul Devi; Syukur, Bambang Abdul; Sutanto, Yusup Subagio
Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan (Abdigermas) Vol. 2 No. 3 (2024): Jurnal Ilmiah Pengabdian Kepada Masyarakat Bidang Kesehatan (Abdigermas)
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/abdigermas.v2i3.309

Abstract

This activity aimed to educate the public about Synbiotic Tempe Extract Krenova Soygurt Products as Functional Drinks for Stunting Prevention. The implementation of activities as community service in the form of health education and counseling on stunting prevention involved 10 lecturers, 12 students along with 9 cadres and 30 people from the Cempaka Integrated Health Post, Wonorejo Village, Gondangrejo, Karanganyar Regency. The social community activity was carried out on August 26, 2024, and the community received a response and enthusiasm through active participation and involvement in the discussion and question and answer sessions. The essence of the implementation and dissemination of the benefits of synbiotic soygurt tempeh can function as a functional drink based on science and technology, halal and economical through a community partnership program carried out sustainably, completely, and meaningfully at the Cempaka Integrated Health Post, Wonorejo Village, Gondangrejo District, Karanganyar Regency to achieve the target of down streaming Kreova health products that are beneficial to the community and support the success of the Government's program in overcoming and reducing the incidence of stunting in Indonesia.
Co-Authors A.A. Ketut Agung Cahyawan W Aldila Puji N Amalia Agustin Arwin Muhlishoh Bambang Abdul Syukur Crisdian S, Hanugrah Ardya Dewi Kusumawati, Dewi Eka Nursafitri Eka Nursafitri Eka Reftiana Z Estuningsih, E Heni Nur Kusumawati Ika Murni W Intan Sari A Intan Sari A. Mellia Silvy Irdianty, Mellia Silvy Nony Puspawati Nurul Devi Ardiani, Nurul Devi Rafika Sari Rahajeng Putriningrum Saelan, Saelan Saptorini, S Saputro, Sutiyo Dani Siti Mardiyah Surya, Nella Tri Sutanto, Magdalena Utari K Wahyu Rima Agustin Wahyuningsih Safitri, Wahyuningsih Winda A. K. Yuliana, Dyah Yusup Subagio Sutanto