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All Journal Medicinus : Jurnal Kedokteran Folia Medica Indonesiana
Arnindita, Jannatin Nisa
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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Failure Factors & Prediction Model of Indonesian Medical Doctor Proficiency & Competency Test (UKMPPD) within COVID-19 Pandemic Salim, Jonathan; Arnindita, Jannatin Nisa; Tandy, Sutiono; Wibisono, Jacobus Jeno; Wibisono, Maria Georgina
Medicinus Vol 11, No 3 (2022): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v10i1.6990

Abstract

Background: Coronavirus Disease 2019 drastically modulate the healthcare world. The pandemic's immense transmission and lethality rate enforce the Indonesian Medical Doctor Proficiency & Competency Test to discard practical measures and rely only on a written exam. These with pandemic social and physical restrictions impede prospective doctors’ learning opportunities leading to easier failure. Henceforth, the present study has high urgency to identify and manage failure factors, especially in the pandemic.Methods: The cross-sectional study examines 75 clinical medical students through purposive analysis with an online questionnaire in August 2021. Data are analyzed with Chi-Square, Mann-Whitney, and binary logistics.Result: Respondents have an average age of 24.15 (1.322) years old, majorly female (82.7%), and pass as first takers (86.7%) with 1.27 (0.949) off-campus tutelage. The significant factors for the test failure are depression and economic status. The study developed a failure prediction model with the area under the curve 0.845, cut-off 366.5, 80.0% sensitivity, and 84.6% specificity.Conclusion: Intrinsic, extrinsic, and academic factors have significant roles in the failure outcome. For this reason, preparation is crucial not only among individuals but also institutions. The study also provides feedback about the importance of mental health and economic status for Indonesian medical students
Failure Factors & Prediction Model of Indonesian Medical Doctor Proficiency & Competency Test (UKMPPD) within COVID-19 Pandemic Salim, Jonathan; Arnindita, Jannatin Nisa; Tandy, Sutiono; Wibisono, Jacobus Jeno; Wibisono, Maria Georgina
Medicinus Vol. 11 No. 3 (2022): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v10i1.6990

Abstract

Background: Coronavirus Disease 2019 drastically modulate the healthcare world. The pandemic's immense transmission and lethality rate enforce the Indonesian Medical Doctor Proficiency & Competency Test to discard practical measures and rely only on a written exam. These with pandemic social and physical restrictions impede prospective doctors’ learning opportunities leading to easier failure. Henceforth, the present study has high urgency to identify and manage failure factors, especially in the pandemic.Methods: The cross-sectional study examines 75 clinical medical students through purposive analysis with an online questionnaire in August 2021. Data are analyzed with Chi-Square, Mann-Whitney, and binary logistics.Result: Respondents have an average age of 24.15 (1.322) years old, majorly female (82.7%), and pass as first takers (86.7%) with 1.27 (0.949) off-campus tutelage. The significant factors for the test failure are depression and economic status. The study developed a failure prediction model with the area under the curve 0.845, cut-off 366.5, 80.0% sensitivity, and 84.6% specificity.Conclusion: Intrinsic, extrinsic, and academic factors have significant roles in the failure outcome. For this reason, preparation is crucial not only among individuals but also institutions. The study also provides feedback about the importance of mental health and economic status for Indonesian medical students
Five Single-Nucleotide Polymorphisms in the PITX2 Gene as Risk Factors for Atrial Fibrillation Putra, Rendra Mahardhika; Dharmadjati, Budi Bakti; Pikir, Budi Susetyo; , Irma Maghfirah; Isaridha, Ilma Alfia; Arnindita, Jannatin Nisa
Folia Medica Indonesiana Vol. 59, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Highlights: • A genetic variable has been identified as an atrial fibrillation risk factor. • Rs2200733 is a type of SNP that increases atrial fibrillation risk, whereas rs3853445, rs6838973, and rs17570669 have the reverse effect. Abstract: Atrial fibrillation (AF) is a highly prevalent arrhythmia. The involvement of molecular mechanisms in increased AF risk remains uncertain. However, the paired-like homeodomain transcription factor 2 or pituitary homeobox 2 (PITX2) gene has been linked to AF development. A comprehensive search was carried out to identify all eligible case-control studies in order to assess the association between five single-nucleotide polymorphisms (SNPs) in the PITX2 gene and the risk of AF. This meta-analysis employed the Review Manager (RevMan) software version 5.3 (Cochrane). There were 13 clinical studies, with a total of 11,961 subjects, that met the inclusion criteria. These subjects consisted of 4,440 patients with AF and 7,521 controls. The meta-analysis of five SNP types in the PITX2 gene was done using crude odds ratios (ORs). This revealed that rs2200733 increased the risk of AF (OR=1.80; 95% CI=1.53-2.11; p=0.0005; I2=80%). On the other hand, the other three SNPs decreased the risk of AF, namely, rs385344 (OR=0.75; 95% CI=0.59-0.95; p=0.002; I2=85%), rs6838973 (OR=0.64; 95% CI=0.51-0.81; p=0.0001; I2=73%), and rs17570669 (OR=0.80; 95% CI=0.65-0.98; p=0.03; I2=70%). However, there was no significant association between rs10033464 and AF (OR=1.21; 95% CI=0.97-1.50; p=0.13; I2=83%). In conclusion, depending on the type, SNPs in the PITX2 gene correlate with AF risk factors, either by alleviating or reducing the risk.
Co-Authors , Irma Maghfirah Budi Susetyo Pikir Dharmadjati, Budi Bakti Isaridha, Ilma Alfia Putra, Rendra Mahardhika Salim, Jonathan Tandy, Sutiono Wibisono, Jacobus Jeno Wibisono, Maria Georgina