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The Ointment of Peel Dragon Fruit (Hylicereus costaricensis) Extract Decreased the Interleukin-2 (IL-2) Expression and the Number of Mononuclear Inflammation Cells toward Open Wound in Skin of Rats Wistar Permata, Fajar Shodiq; Febrianto, Ahmad
Veterinary Biomedical and Clinical Journal Vol. 1 No. 2 (2019)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Open wounds healing is need more time because of the long inflammatory phase. Dragon fruit skin contains flavonoids and vitamin C which function as anti-inflammatory and cell regeneration. The purpose of this study was to determine the therapeutic effects of dragon fruit skin extract ointment (Hylicereus costaricensis) on the area of IL-2 expression and the number of mononuclear inflammatory cells in skin tissue in open wounds of rats (Rattus norvegicus) for 6 days of treatment. As many as 20 male rats, Â± 180 grams, Wistar were divided into 5 groups namely negative control, positive control, ointment of dragon fruit skin extract with concentration of 5% (P1), concentration of 10% (P2) and concentration of 15% (P3). Wound formed as dorsal skin biopsy of dorsal 1x1 cm. Ointment was given topically 2x/day for 6 days. Rats were euthanized on day 7th and the skin tissues of the wound area were collected. The number of mononuclear inflammatory cells was counted in skin slides of HE staining and Expression Area expression of IL-2 was measured by ImmunoRatioÂ® in immunohistochemical slides. Data were analyzed statistically using One Way ANOVA and Tukey Post Hoc Test. The results showed that dragon fruit skin extract ointment was able to reduce significantly (p<0.05) for area expression of IL-2 and the number of mononuclear inflammatory cells and the best concentration of ointment for treatment was 15%. This is due to the effect of flavonoids as anti-inflammatory and vitamin C as a trigger for cell regeneration. The conclusion of the study was that ointment of dragon fruit peel able to become a candidate for therapeutic medicine for open wounds.

Influencer Impact; Solusi Produsen Dalam Mempromosikan Produk Febrianto, Ahmad; Salsabila, Saida
Al-Urban: Jurnal Ekonomi Syariah dan Filantropi Islam Vol. 6 No. 1 (2022)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/alurban_vol6/is1pp73-86

Penelitian ini menggunakan pendekatan Kualitatif agar dapat menghasilkan uraian. Penelitian ini bertujuan untuk memahami dan menganalisis mengenai strategi dalam mempromosikan produk dengan menggunakan Endorsment. Dalam perkembangan teknologi untuk saat ini apalagi dengan adanya internet sangat cepat dan sangat berdampak hampir kesegala bidang pun baik kehidupan yang dimana untuk saat ini dipengaruhi oleh internet. Dengan adanya internet sangat memberikan peluang bagi pemasaran ataupun marketing sangat dibutuhkan, adanya internet berdampak dan munculnya sebuah periklanan digital yang dimana para pemilik usaha mulai menjadikan media sebagai media promosi, karena bisa menciptakan peluang terhadap sebuah perusahaan.

PENGARUH BIAYA OPERASIONAL TERHADAP PROFITABILITAS PT INDOFOOD SUKSES MAKMUR Tbk PERIODE 2020-2023 Febrianto, Ahmad; HIilda Zamrotul Firdausiah
Jurnal Dinamika Ekonomi Syariah Vol 12 No 1 (2025): Jurnal Dinamika Ekonomi Syariah
Publisher : Program Studi Ekonomi Syariah, Institut Agama Islam Pangeran Diponegoro Nganjuk

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53429/jdes.v12i1.1300

PT. Indofood Sukses Makmur is a well-known processing company in Indonesia. The purpose of this study is to determine the effect of operating costs on profitability at PT. Indofood Sukses Makmur Tbk for the period 2020-2023. Where the tendency of operating costs has increased while profitability at PT Indofood has increased growth every year. The method used in this study is a descriptive method using a quantitative approach. The data used is secondary data in the form of the company's financial reports for 2020-2023. Operating costs have experienced rapid growth every year. To determine the effect of operating costs on profitability, statistical testing is used. Statistical testing is used in normality tests, the use of regression, correlation coefficients, determination coefficients, t-tests also using the SPSS 16 application. From the results of simple linear regression calculations and correlation coefficients, operating costs and profitability have a Pearson correlation value of 0.641, which is a strong correlation level. so that the level of influence of operating costs on profitability at PT Indofood is 0.213 and the rest, namely 0.787, is influenced by other factors that were not studied. The results of the t-test value obtained t0 0,520 ≥ ta 2,920, so this value means that operational costs do not affect profitability.

PENGARUH BIAYA OPERASIONAL TERHADAP PROFITABILITAS PT INDOFOOD SUKSES MAKMUR Tbk PERIODE 2020-2023 Febrianto, Ahmad; HIilda Zamrotul Firdausiah
Jurnal Dinamika Ekonomi Syariah Vol. 12 No. 1 (2025): Jurnal Dinamika Ekonomi Syariah
Publisher : Program Studi Ekonomi Syariah, Universitas Pangeran Diponegoro Nganjuk

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53429/jdes.v12i1.1300

PT. Indofood Sukses Makmur is a well-known processing company in Indonesia. The purpose of this study is to determine the effect of operating costs on profitability at PT. Indofood Sukses Makmur Tbk for the period 2020-2023. Where the tendency of operating costs has increased while profitability at PT Indofood has increased growth every year. The method used in this study is a descriptive method using a quantitative approach. The data used is secondary data in the form of the company's financial reports for 2020-2023. Operating costs have experienced rapid growth every year. To determine the effect of operating costs on profitability, statistical testing is used. Statistical testing is used in normality tests, the use of regression, correlation coefficients, determination coefficients, t-tests also using the SPSS 16 application. From the results of simple linear regression calculations and correlation coefficients, operating costs and profitability have a Pearson correlation value of 0.641, which is a strong correlation level. so that the level of influence of operating costs on profitability at PT Indofood is 0.213 and the rest, namely 0.787, is influenced by other factors that were not studied. The results of the t-test value obtained t0 0,520 ≥ ta 2,920, so this value means that operational costs do not affect profitability.

Comparative Pollution Index Assessment of Seawater Quality at Two Coastal Beaches in Lamongan Nasihah, Mimatun; Zufar Assahbantar, Azhar; Fauzi, Mohammad; Febrianto, Ahmad; Dwi Yanti, Sylvia; Niswatin, Nanis
Biotropika: Journal of Tropical Biology Vol. 14 No. 1 (2026)
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.biotropika.2026.014.01.07

Different coastal activities may exert varying environmental pressures on marine water quality, even in geographically adjacent areas. This study aimed to compare the marine water quality at Kemantren Beach and Lorena Beach, Paciran District, Lamongan Regency, which are characterised by different coastal activity pressures, and to assess the water quality status using the Pollution Index (PI). This research employed an observational approach with a descriptive-comparative design. The marine water quality parameters included Total Dissolved Solids (TDS), Total Suspended Solids (TSS), pH, Dissolved Oxygen analysed (DO), turbidity, and temperature. Data were analysed descriptively and comparatively using the Mann–Whitney U test and evaluated against marine water quality standards based on Government Regulation No. 22 of 2021, Appendix VIII. The results showed that all measured water quality parameters at both locations were within the permissible limits for marine tourism and marine biota. However, distinct differences in water quality characteristics were observed between the two beaches. Kemantren Beach exhibited higher TSS and turbidity values compared to Lorena Beach, which were associated with fishing boat activities and sediment resuspension. Pollution Index analysis indicated that both sites were classified as lightly polluted, with a higher PI value at Kemantren Beach. These findings suggest the presence of early-stage environmental pressure resulting from different anthropogenic activities. This study demonstrates that the Pollution Index approach provides a comprehensive assessment of marine water quality and can serve as a scientific basis for sustainable coastal management.

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