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All Journal Madu : Jurnal Kesehatan Journal of Experimental and Clinical Pharmacy (JECP)
Damiti, Sukmawati
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Phytochemical Study of Green Meniran Herb (Phyllanthus niruri L.) and Red Meniran Herb (Phyllanthus urinaria L.) in Jekan Raya Sub-district of Palangka Raya City, Central Kalimantan Province Damiti, Sukmawati; Mashar, Harlyanti Muthma’innah; Yusuf, Baharuddin
Journal of Experimental and Clinical Pharmacy (JECP) Vol 4, No 1 (2024): February 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v4i1.891

Abstract

Kalimantan is one of the islands in Indonesia that is famous for its rich biodiversity. Knowledge about the use of traditional medicine using plants has been passed down from generation to generation among the ethnic natives of Kalimantan. One of the typical Kalimantan plants that is efficacious as traditional medicine and contains various potential secondary metabolites is meniran. Based on ethnobotanical studies in Central Kalimantan, meniran is boiled to treat fever, dysentery, jaundice, malaria, therefore further research is needed for the chemical content of meniran which is efficacious. This study aims to determine the phytochemical of green meniran herb (Phyllanthus niruri L.) and red meniran herb (Phyllanthus urinaria L.). Determination of plant samples was carried out for both types of meniran. Then processing, extraction and identification of chemical content. The yield values of each extract obtained were 7.40% and 8.76%. As for the results of phytochemical studies, green and red meniran herb both contain alkaloid, tannins and flavanoids, but green meniran is indicated to have steroid content and red meniran contains triterpenes. Secondary metabolites possessed by these two types of meniran plants are beneficial for health, including as antioxidants, antibacterial, antiviral, anticancer and a number of pharmacological activities that are significant in improving one's health and minimizing the risk of infection by pathogens. However, further research is needed to test the activity of the content of these two types of meniran as a basis for the manufacture of traditional medicines.
Uji Efektivitas Antihiperglikemik Ekstrak Etanol Bunga Rosella (Hibiscus sabdariffa L) yang di Induksi Sukrosa pada mencit Jantan (Mus musculus) Abdulkadir, Widy Susanti; Akuba, Juliyanty; Rahman, Muh. Nadzirul; Damiti, Sukmawati
Madu : Jurnal Kesehatan Vol 13, No 1 (2024): Juni 2024
Publisher : Program Studi DIV Kebidanan Fakultas Ilmu Kesehatan Universitas Muhammadiyah Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31314/mjk.13.1.67-75.2024

Abstract

Diabetes mellitus is a serious condition characterized by an increase in glucose levels (GDS) ≥ 200 mg/dL due to the body’s inability to produce the hormone insulin effectively. Many plants have antidiabetic properties, including the roselle (Hibiscus sabdariffa L.) flower, which has been rarely studied scientifically. This research aims to determine the most effective dose of ethanol extract of roselle flower for antihyperglycemic activity in male mice induced with a 90% sucrose solution. This research employs the Oral Sucrose Tolerance Test (OSTT) method. Activity tests in mice were conducted on 5 treatment groups: Group I was the negative control (Na-CMC 1% w/v), Group II was the positive control (acarbose), Group III received ethanol extract at a dose of 250 mg/kgBW, Group IV received ethanol extract at dose of 500 mg/kgBW, and Group V received ethanol extract at a dose of 750
Co-Authors Baharuddin Yusuf Harlyanti Muthma'innah Mashar Rahman, Muh. Nadzirul Widy Susanti Abdulkadir