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Evaluasi Efek Samping Penggunaan Obat Tetes Mata Kortikosteroid Pada Pasien Pasca Operasi Katarak (Penelitian dilakukan di Instalasi Farmasi Klinik Mata KMU Madura) Solihah, Riyadatus; Umar, Rizal
NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 15 No 3 (2024): SEPTEMBER
Publisher : NHM PRESS

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Abstract

Corticosteroids are natural steroid hormones in humans produced by the adrenal cortex gland that have a function to treat inflammation or autoimmune disorders in the body. In the case of eye disease, corticosteroid drugs can take the form of eye drops that are widely used in post-cataract surgery patients, which function to reduce inflammation that occurs in the interior segment which sometimes has no clear cause. The purpose of this study was to determine the side effects that can occur in the use of corticosteroid drugs after cataract surgery. This study was conducted with crossectional method which was analysed descriptively using universal sampling method. This activity uses inclusion and exclusion criteria. The sampling method uses non-random sampling with the time limited sampling method, namely taking all patient's Health Medical Record (RMK) data. The results and discussion of this study were conducted at the KMU Madura Clinic Pharmacy Installation involving a number of post-cataract surgery patients who used corticosteroid eye drops. The use of corticosteroid eye drops has the potential to cause various side effects. The most common side effects encountered in patients are blurring, stinging, red eyes, and itching. The most widely used eye drops were prednisolone by 53.3%. Based on the above results, it can be described that the length of use of corticosteroid eye drops in patients after cataract surgery at the KMU madura eye clinic pharmacy installation is more than 30 days.
Pengaruh Lama Penggunaan Kb Suntik (DMPA) Terhadap Kadar Low Density Lipoprotein (LDL-C) Solihah, Riyadatus; Umar, Rizal
NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 13 No 2 (2022): JUNI
Publisher : NHM PRESS

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Abstract

DMPA may cause increased lipophysis or hydrolysis. Then the large amount of free fatty acids is carried to the liver, causing increased triglyceride synthesis and VLDL secretion. In the state of insulin resistance VLDL becomes increased in circulation and can cause an increase in Low Density Lipoprotein (LDL), LDL is mostly formed from VLDL. The purpose of this study was to determine the effect of injectable birth control (DMPA) on Low Density Lipoprotein (LDL) levels. The research method used in this study is analytic with a cross sectional approach. The technique used was purposive sampling in a population of 60 respondents and a sample of 24 respondents in women who used DMPA injectable birth control in Ponkesdes Fariyah.S.ST. The results obtained from 24 samples showed as many as 12 samples (50%) using DMPA injections above 3 years had higher LDL cholesterol levels compared to 12 samples (50%) using DMPA injections above 5 years. The results of statistical tests conducted with the Independent Samples Test test obtained a significant value of 0.793 (p ≥ 0.05) so it can be concluded that there is no difference in LDL-cholesterol levels in the use of injectable birth control for more than 3 years and more than 5 years. For women who use DMPA injectable birth control, it is advisable to check LDL levels more often so that the LDL levels in the blood can be known.