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ANALYSIS OF APO-B SERUM LEVELS IN BALB/C MICE HYPERCHOLESTEROLEMIC AGAINST TEMULAWAK EXTRACT (Curcuma xanthoriza Roxb) Riyadatus Solihah; M. Shofwan Haris; Yogi Khoirul Abror
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 1 No 1 (2019): The Value, Importance, and Oversight of Health Research
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v1i1.799

APO–B Serum levels is the most predictive value for the incidence of atherosclerosis and coronary heart disease. Curcuma xanthorrhiza Roxb contains curcumin, which can be used as an antioxidant, anti–inflammatory and antihypercholesterol. The mechanism of curcumin contained in ginger to reduce cholesterol is due to its function as a cholagoga or bile stimulant. This study aims to determine the effect of temulawak extract on the levels of APO–B Serum in hypercholesterolemia mice. This research were a true experimental study with a post–test only control group design carried out in February 2018. The extraction As much as 25 mice were divided into 5 groups where are group consisted of 5 mice. Positive control group (K+) were treated with high cholesterol feed and water, negative control group (K–) were given standard feed and water, treatment group 1 (P1) were given high cholesterol food and 25mg/kg BW of curcuma extract for 14 days, treatment group 2 (P2) were treated with foods high in cholesterol and 50mg/kg BW of curcuma extract for 14 days and treatment group 3 (P3) treated with high cholesterol and ginger extract 75mg/kg BW for 14 days. Examination of APO–B levels were measured using the spectrophotometric method. Data were analyzed using One–Way Anova. The results showed that the average of APO–B level at (K+) was 209.7 ± 1.02 mg / dL, at (K–) 115.3 ± 1.04 mg / dL, at (P1) 180.4 ± 1.07 mg / dL, at (P2) 147.6 ± 1.12 mg / dL, at (P3) 119.1 ± 1.10 mg / dL. Based on the results of statistical test it was found that there was a significant decrease in APO–B levels with p–value= 0.001 at alpha 0.05 (p <α).

IDENTIFIKASI TELUR NEMATODA USUS SOIL TRANSMITTED HELMINTHS (STH) PADA KUKU JARI TANGAN PEKERJA TEMPAT PENITIPAN HEWAN METODE PENGAPUNGAN (FLOTASI) MENGGUNAKAN NaCl Dwi Aprilia Anggraini; Norma Farizah Fahmi; Riyadatus Solihah; Yogi Abror
Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal Vol. 11 No. 2 (2020): Jurnal Ilmu Kesehatan Bhakti Husada: Health Science Journal
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Kesehatan Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34305/jikbh.v11i2.166

Worms is an endemic, chronic and zoonotic disease. Soil Transmitted Helminths (STH) are a class of worms that can cause worm infections. STH infection can be transmitted to humans in various ways, one of which is through worm eggs attached to dirty fingernails so that it can pose a risk to health. This study aims to identify STH intestinal nematode eggs on fingernails using the flotation method. This type of research is a descriptive analysis using a laboratory approach method. 20 samples were taken by purposive sampling in four different animal care centers and then identified by the floating method. From the identification results, it was found that 10% of STH intestinal nematode eggs were contaminated on fingernails using the floatation method and 90% were not contaminated with STH intestinal nematode eggs. The types of worm eggs found were Trichuris sp and Hookworm. It is recommended that workers be able to maintain cleanliness of fingernails and wear personal protective equipment (PPE) before starting work.

ANALISIS KADAR APO-A1 SERUM PADA TIKUS PUTIH STRAIN WISTAR (Rattus novergicus) DISLIPIDEMIA TERHADAP PEMBERIAN EKSTRAK KULIT BUAH APEL [Malus sylvestris Mill] VARIETAS ROOM BEAUTY Riyadatus Solihah
NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 10 No 1 (2018): SEPTEMBER
Publisher : NHM PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36089/nu.v10i1.140

Dyslipidemia is a disorder of lipid metabolism characterized by increased levels of total cholesterol, triglycerides, low density lipoprotein or a decrease in high-density lipoprotein in the blood, while hyperlipidemia is a condition where there are elevated levels of lipids in ie blood triglycerides, kolersterol or both. This state tehadap high risk of cardiovascular disease (CVD).This research uses experimental research design pure (True Experimental) and the study design used was the randomized post test only control group design, sample number 32 strain Wistar rats (RattusnovergicusWistar strain) 3-4 month old male weighing approximately 100-120 grams were divided into 4 groups, consisting of 1 control group were only given a high-fat diet feed for 28 days, and 3 treatment groups were given a high-fat diet feeding and apple skin extract with 3 different doses of 0,52 mg / kg bw , 1,04 mg / kg bw, 1,58mg / kg for 10 days. Data analysis with inferensial analysis include analysis of normality test with Shapiro and its homogeneity analysis with test Levene Test. If normal and homogeneous data, then continued by annova test one way with a level of significance of the test, at variance p=0.05 . the test variance be obtained levels of were significant with Apo A1 obtain p= 0.001, data have p <0.05, which means there is a significant effect of extract of Apple Skin to the increased levels of and Apo A1 in the rat. Apple skin extract contains pectin that activated PPAR α can increase the levels of serum Apo-A1 in circulation which is the main and largest of protein fractions role in cholesterol transport. Keywords: Apple Skin, Apo-A1

Increasing students' interest and knowledge about herbs in elementary school Devi Anggraini Putri; Riyadatus Solihah; Rizka Efi Mawli
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol 7, No 4 (2022): November 2022
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v7i4.8193

Herbs is not only a potent Indonesian herbal medicine but also the ancestor tried to keep the preservation of herbs. Therefore, knowledge about herbs is important to be preserved from an early age. However, currently, the interest of Indonesian children in consuming herbs tends to decrease. The stigma that herbs is bitter is the reason why herbs is unlikeable. Based on the analysis of the demographic condition in Bangkalan, the quality of education is still low, interest and knowledge about herbs is also low. The purpose of this program is to increase students' interest and knowledge about herbs at SDN Demangan 3 Bangkalan. The methods are socializing, implementing educational games about herbs, and drinking herbs together. Furthermore, students' interest in herbs was evaluated by using a questionnaire. Meanwhile, students' knowledge about herbs was analyzed and evaluated based on the results of the pre-test and post-test. The results of the program showed that students’ interest in herbs increased by 83% after a learning media namely herbs snake ladder game was applied. In addition, students' knowledge about herbs also increased by 76% from 24 respondents. Thus, this program is recommended to increase the interest and knowledge of elementary school students about herbs.

Konseling Dagusibu Obat sebagai Upaya Peningkatan Pemahaman pada Remaja di SMPN Satap Bujur Barat Pamekasan April Nuraini; Riyadatus Solihah; M Shofwan Haris; Ratri Rokhani; Metta Kristina; Rizal Umar Rahmadani; Dianita Rahayu Puspitasari
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 5, No 1 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v5i1.7478

Fasilitas dan informasi kesehatan yang minimal menyebabkan rendahnya pemahaman masyarakat mengenai informasi pengelolaan obat dan swamedikasi. Informasi pengelolaan obat yaitu dapatkan, gunakan, simpan, buang obat yang dikenal sebagai DAGUSIBU. Tujuan konseling ini yaitu mengenalkan DAGUSIBU obat di kalangan remaja. Peserta dari kegiatan ini sebanyak 34 siswa Sekolah Menengah Pertama Negeri (SMPN) Satap Bujur Barat Pamekasan yang dilaksanakan pada tanggal 10 Desember 2022. Peserta secara langsung mendapatkan leaflet yang berisi materi DAGUSIBU. Penjelasan materi dengan metode ceramah melalui media powerpoint yang didukung dengan perlengkapan peraga obat-obatan sebagai contoh penerapan DAGUSIBU. Pelaksanaan kegiatan ini meliputi pretest, konseling tentang DAGUSIBU obat, diskusi, tanya jawab dan ditutup dengan posttest. Dari hasil evaluasi konseling mengenai DAGUSIBU obat menunjukkan respon yang sangat baik, ditandai dengan atensi peserta melalui diskusi dan tanya jawab. Hasil dari kegiatan ini menunjukkan bahwa adanya peningkatan rata-rata skor pretest dan posttest yaitu sebesar 107%. Kesimpulan dari kegiatan ini menunjukkan bahwa adanya peningkatan pemahaman mengenai pengelolaan obat DAGUSIBU setelah diberikan konseling.Minimal health facilities and Information cause low public understanding of drug management information and self-medication. Drug management information, i.e. gets, uses, stores, and disposes of drugs, is known as DAGUSIBU. The purpose of this counselling is to introduce DAGUSIBU drugs among adolescents. The participants of this activity were 34 students of Satap Bujur Pamekasan Junior High School (SMPN), which was held on December 10, 2022. Participants directly received a leaflet containing DAGUSIBU material. Explanation of the material by the method of lectures through the media PowerPoint supported with props drugs as an example of the application of DAGUSIBU. The implementation of this activity includes a pretest, counselling about DAGUSIBU drugs, discussion, question and answer and closed with a posttest. The evaluation of socialization about DAGUSIBU drugs showed a very good response, marked by participants' attention through discussion and question and answer. This activity's results showed an increase in the average pretest and posttest scores of 107%. This activity's conclusion shows an increased understanding of DAGUSIBU drug management after counselling.

RED BETEL LEAF EXTRACT SERUM (Piper ornatum) AS AN ALTERNATIVE ANTI-HEAD LICE TREATMENT Rizal Umar Z; Riyadatus Solihah; M Shofwan Haris
NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 13 No 3 (2022): SEPTEMBER
Publisher : NHM PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Lice (Pediculus humanus capitis) or known as head lice are ectoparasites that live on the human scalp, the main symptom felt is itching on the scalp caused by lice bites on the scalp. Lice are often found in children aged 7-10 years and also in adults, lice can live on the scalp, body and hair of the pubic area, and can cause itching, scabs, loss of concentration, lack of sleep, and lack of confidence. One way to overcome this is to use anti-lice shampoo. Some studies state that betel leaf extract can kill head lice. Thus, article aims to find out what serum concentration of red betel leaf extract (Piper ornatum) is effective against the death of head lice (Pediculus humanus capitis).

PERBEDAAN SEDIMEN URINE Ca-OKSALAT PADA KONSUMEN AIR SUMUR DAN AIR MINERAL DI DUSUN KEMEREH DEJEH Riyadatus Solihah; Yogi Khoirul Abror; M. Shofwan Haris
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 15 No 1 (2023): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v15i1.2108

Air merupakan kebutuhan penting bagi makhluk hidup dimuka bumi, terutama bagi manusia. Mayoritas masyarakat yang hidup di desa memiliki kebiasaan mengkonsumsi air sumur. Kondisi geografis yang relatif tandus dan kering serta berada pada hamparan batuan kapur membuat kondisi air sumur mengandung butiran-butiran kapur yang dapat menimbulkan permasalahn kesehatan seperti batu ginjal akibat penumpukan sedimen pada nefron. Tujuan dari penelitian ini adalah mengetahui perbedaan hasil sedimen urine Ca-oksalat pada konsumen air sumur dan air mineral. Metode penelitian yang digunakan dalam penelitian ini adalah eksperimental dengan desain penelitian cross sectional. Teknik sampling yang digunakan purposive sampling dengan populasi 233 responden dan didapat 25 responden konsumen air sumur dan 25 responden konsumen air mineral di Dusun Kemereh Dejeh. Hasil yang didapatkan dari 25 sampel urine konsumen air sumur menunjukkan 9 sampel (36%) positif Ca oksalat, sedangkan 16 sampel (64%) negatif Ca oksalat. 25 sampel konsumen air mineral negatif Ca oksalat karena tidak ditemukan Ca oksalat. Hasil uji statistika yang dilakukan dengan dengan uji Wilcoxon didapatkan nilai signifikan 0,003 (p ≤ 0,05) sehingga dapat disimpulkan terdapat perbedaan hasil sedimen urine Ca oksalat pada konsumen air sumur dan air mineral.

PERBEDAAN SEDIMEN URINE Ca-OKSALAT PADA KONSUMEN AIR SUMUR DAN AIR MINERAL DI DUSUN KEMEREH DEJEH Riyadatus Solihah; Yogi Khoirul Abror; M. Shofwan Haris
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 15 No 1 (2023): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v15i1.2108

Air merupakan kebutuhan penting bagi makhluk hidup dimuka bumi, terutama bagi manusia. Mayoritas masyarakat yang hidup di desa memiliki kebiasaan mengkonsumsi air sumur. Kondisi geografis yang relatif tandus dan kering serta berada pada hamparan batuan kapur membuat kondisi air sumur mengandung butiran-butiran kapur yang dapat menimbulkan permasalahn kesehatan seperti batu ginjal akibat penumpukan sedimen pada nefron. Tujuan dari penelitian ini adalah mengetahui perbedaan hasil sedimen urine Ca-oksalat pada konsumen air sumur dan air mineral. Metode penelitian yang digunakan dalam penelitian ini adalah eksperimental dengan desain penelitian cross sectional. Teknik sampling yang digunakan purposive sampling dengan populasi 233 responden dan didapat 25 responden konsumen air sumur dan 25 responden konsumen air mineral di Dusun Kemereh Dejeh. Hasil yang didapatkan dari 25 sampel urine konsumen air sumur menunjukkan 9 sampel (36%) positif Ca oksalat, sedangkan 16 sampel (64%) negatif Ca oksalat. 25 sampel konsumen air mineral negatif Ca oksalat karena tidak ditemukan Ca oksalat. Hasil uji statistika yang dilakukan dengan dengan uji Wilcoxon didapatkan nilai signifikan 0,003 (p ≤ 0,05) sehingga dapat disimpulkan terdapat perbedaan hasil sedimen urine Ca oksalat pada konsumen air sumur dan air mineral.

EVALUATION OF THE LEVEL OF COMMUNITY KNOWLEDGE ABOUT HOW TO USE AND ANTIBIOTIC RESISTANCE IN DUPOK VILLAGE, BANGKALAN REGENCY Rizal Umar; Riyadatus Solihah; Mufarika -
INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Vol 7 No 2 (2023): VOLUME 7 ISSUE 2 AUGUST 2023
Publisher : Departement Research and Community Engagement Bina Sehat PPNI Institute of Health Science, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29082/IJNMS/2023/Vol7/Iss2/476

Antibiotics are drugs that we often encounter in everyday life, not infrequently doctors often prescribe this one drug, but in use in the community there are still often errors in consuming antibiotics resulting in antibiotic resistance or resistance to an antibiotic. The occurrence of misuse of antibiotics is caused by lack of public knowledge and lack of education from medical personnel in hospitals. Low level of knowledge about the use of antibiotics can cause inappropriate use of antibiotics, so there is a risk of causing antibiotic side effects. Providing education is one way that can be used to increase knowledge about the rational use of antibiotics. The purpose of this study is to determine the level of public knowledge about how to use antibiotics and antibiotic resistance. The study was conducted in Dupok Village, Bangakalan Regency, this type of research was cross sectional through a survey with questionnaire media. Sampling was carried out using the cluster sampling method involving 100 households (Family Heads). The research instrument used was a closed questionnaire with a total of 10 questions. The data obtained is then analyzed descriptively.

OCCURRENCE OF GLAUCOMA INCIDENCE AND DIABETES MELLITUS AT KMU MADURA EYE CLINIC Riyadatus Solihah Solihah; M. Shofwan Haris; Rizal Umar
INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Vol 7 No 2A (2023): VOLUME 7 ISSUE 2A: SPECIAL ISSUE - HEALTH SCIENCE 2023
Publisher : Departement Research and Community Engagement Bina Sehat PPNI Institute of Health Science, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29082/IJNMS/2023/Vol7/Iss2A/526

Glaucoma is a disease of the eye characterized by increased intraocular pressure, atrophy of the optic nerve papillae, and reduced vision. Glaucoma can be caused by systemic disease or local disease of the eye. One of the systemic disorders that can trigger glaucoma is diabetes mellitus (DM). The purpose of this study was to determine the relationship between the incidence of glaucoma and a history of diabetes mellitus at the KMU Madura eye clinic. This research was conducted using analytic observational method with a case-control design using a retrospective approach. The sample in this study was obtained by quota sampling technique with a total of 557 patients. Patient data was taken within a period of 12 months from January 2022 – December 2022. Based on the results of observational analysis, it was found that 203 patients (36.44%) had glaucoma with a history of diabetes mellitus, while 354 patients (63.56%) had glaucoma without a history of diabetes mellitus. The results of the Chi-Square test between the prevalence of Glaucoma and a history of Diabetes Mellitus showed a p value = 0.000 (p≤0.05) and the results of the Fisher test between each type of Glaucoma and a history of Diabetes Mellitus only Primary Open Angle Glaucoma only showed there was relationship with the value of p value = 0.004 (p <0.05). The results of this study can be concluded that there is a significant relationship between the prevalence of glaucoma and a history of diabetes mellitus.

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