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All Journal Heart Science Journal CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Aufazhafarin, Nadhifa Tanesha
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Smoking Behaviors, Dietary Patterns, and Dyspepsia among Indonesian Adults in 2022 Aprilawati, Dwi; Davis, Gerald Sebastian; Nuha, Muftihana Hanin; Ollyvia, Zsa Zsa; Fadilla, Aulia Nur; Rahmadanti, Ananda; Aufazhafarin, Nadhifa Tanesha; Kloping, Nabila Ananda; Priyambodo, Pamarga; Watang, Andreas Novaldi; Lumaksono, Nandiwardhana Dhira Pranaya; Munir, Sirazul
Current Internal Medicine Research and Practice Surabaya Journal Vol. 5 No. 2 (2024): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v5i2.58592

Abstract

Introduction: The global prevalence of dyspeptic syndrome among adults was estimated to be 1.8–57% in 2014, with an average of 20.8%. In a pilot survey involving 30 respondents, we found 21 acute respiratory infections, 16 dyspeptic syndromes, and 6 hypertension cases. Smoking was observed in 70% of the total respondents. This was the basis for conducting additional research in 2022 to examine the relationship between dyspepsia, smoking behaviors, and dietary patterns among adults in Krajan Hamlet, Malang, Indonesia. Methods: This quantitative study used an analytical observational design with a cross-sectional approach. The sample consisted of 70 adults aged 18–65, selected by random sampling. The collected data were analyzed using the Chi-squared test (p<0.05). Results: The prevalence rate for dyspepsia was 44.3%. Among them, 67.1% were smokers (both frequent and non-frequent), and 32.9% were non-smokers (including former and passive). The active smokers had a smoking duration of >2 years and smoked >10 cigarettes daily. A total of 11.4% of subjects exhibited eating habits of consuming trigger foods that put them at a high risk for dyspepsia. Specifically, 42.0% of subjects had an eating interval of >6 hours, while 87.1% had a meal frequency that led to a high risk of developing dyspepsia. There was a significant relationship between a high-risk diet and dyspeptic syndrome (p=0.037). Conclusion: High-risk diets exhibited a relationship with the prevalence of dyspeptic syndrome. Early detection is crucial in an effort to prevent and reduce the incidence and complications of dyspeptic syndrome.   Highlights: 1. This study investigated the relationship between dyspepsia, smoking behaviors, and dietary patterns, which are often overlooked, particularly among those living in rural areas. 2. The findings of this study are anticipated to raise awareness regarding the detrimental impacts of smoking and unhealthy diets on dyspepsia.
A systematic review and meta-analysis of drug-coated balloons versus drug-eluting stents in de novo and in-stent restenosis coronary bifurcation lesions Dzikrul Haq Karimullah, Muchammad; Saputra, Pandit Bagus Tri; Alkaff, Firas Farisi; Oktaviono, Yudi Her; Nugraha, Ricardo Adrian; Faizah, Novia Nurul; Widiarti, Wynne; Aufazhafarin, Nadhifa Tanesha; Doman, Zahras Azimuth; Sahara, Rendy Asmaradhana; Niazta, Nisa Amnifolia
Heart Science Journal Vol. 7 No. 3 (2026): Predicting Restenosis in Coronary Artery Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.03.6

Abstract

Background: Coronary bifurcation lesions are notoriously difficult to treat percutaneously and may require advanced techniques. Drug-eluting balloons (DCBs) have several advantages over drug-eluting stents (DESs), including the ability to maintain arterial physiology, reduce the risk of stent thrombosis, and eliminate the need for permanent metal implants. However, it remains uncertain which treatment will work best. Objective: This study evaluated DCBs and DESs in coronary bifurcation lesions using subgroup analyses based on lesion type and location. Methods: We searched scientific databases for relevant publications up until May 31, 2025. In order to synthesise the results, a random-effects model was employed. To determine the possibility of bias, the ROBINS-I was utilized, and to measure the level of heterogeneity across the studies, the I³ statistic was used. Results were analyzed clinically and angiographically. This subgroup analysis focused on the position of the bifurcation and the kind of lesion (new, internal, or all sites). Result: Eleven research were deemed eligible for inclusion. There was a trend toward fewer major adverse cardiac events (MACE) with DCB compared to DES in the whole cohort, however the trend was not statistically significant (OR0.77, 95% CI0.58-1.02; p=0.07; I²=0%). Both major adverse cardiac events (MACE) and target lesion revascularization (TLR) were significantly reduced in de novo bifurcations when DCB was used (OR0.61, 95% CI 0.41-0.89; p=0.01). Myocardial infarction, target vessel revascularization, in-stent thrombosis, and cardiac mortality were not significantly different among groups. Both the early and late lumen loss and gain seen on angiograms were within the normal range. Conclusion: In de novo bifurcation lesions, DCB demonstrates reduced MACE and TLR versus DES, supporting its role as a stent-free alternative. Randomized controlled trials with greater sample sizes and prolonged follow-up are warranted.
Co-Authors Alkaff, Firas Farisi Aprilawati, Dwi Davis, Gerald Sebastian Doman, Zahras Azimuth Dzikrul Haq Karimullah, Muchammad Fadilla, Aulia Nur Faizah, Novia Nurul Kloping, Nabila Ananda Lumaksono, Nandiwardhana Dhira Pranaya Munir, Sirazul Niazta, Nisa Amnifolia Nugraha, Ricardo Adrian Nuha, Muftihana Hanin Ollyvia, Zsa Zsa Priyambodo, Pamarga Rahmadanti, Ananda Sahara, Rendy Asmaradhana Saputra, Pandit Bagus Tri Watang, Andreas Novaldi Widiarti, Wynne Yudi Her Oktaviono, Yudi Her