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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kesehatan Andalas Indonesian Journal of Community Services
Intisari, Dewi
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Humanities Health Professions Medicine & Pharmacology Social Sciences

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Multiple intrathoracic thrombosis detected on ct scan in patient with antiphospholipid antibody syndrome: case report Safarini, Bekti; Intisari, Dewi
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2023): December 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i2.1663

Abstract

Antiphospholipid antibody syndrome (APS) is the clinical correlation between antiphospholipid antibodies and hypercoagulability syndrome. The prevalence of APS in the general population is undetermined. APS disease carries a notable risk of vascular thrombosis. CT scan is the preferred imaging method for assessing thrombosis, although the timing of image acquisition should be considered. The case report detailed the discovery of many intrathoracic thromboses on a CT scan of a patient diagnosed with the uncommon condition APS. Case study: A 34-year-old woman was hospitalized due to dyspnea, cough, and a 3 kg weight loss over a three-month period. She has a background in Deep Vein Thrombosis (DVT). The test results showed abnormalities in protein C, protein S, and high D-dimer levels. The CT scan revealed numerous intrathoracic thrombi. Antiphospholipid syndrome (APS) is an immunological condition that elevates the likelihood of blood clot formation, resulting in thrombosis inside the arteries and veins. The approximate occurrence rate of APS is five occurrences per 100,000 individuals annually. Antiphospholipid syndrome (APS) leads to the formation of blood clots in the legs, a condition referred to as deep vein thrombosis (DVT). This patient had a history of deep vein thrombosis (DVT) and many blood clots within the chest cavity. A CT scan revealed persistent blood clots in the main pulmonary artery and the right and left pulmonary arteries. Antiphospholipid syndrome (APS) can lead to the formation of blood clots in both arteries and veins. CT scan is the preferred method for evaluating thrombosis, and numerous phases are required to examine all blood arteries.
Validation of sputum gram stain and culture for diagnosis of pneumonia in critically iii patient: a retrospective observational study Rahayu, Rahayu; Masfiyah, Masfiyah; Intisari, Dewi; Putri, Indri Hapsari; Hibatullah, M. Adam
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2023): December 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i2.32809

Abstract

Validation of culture results based on direct gram stain plays a vital role in differentiating pathogens' cause of infection or colonization in pneumonia cases. Our study aims to evaluate the validation of diagnostic microbiology based on gram stain and culture compared to chest radiography in critically ill patients with suspected pneumonia. This was a single-center retrospective data analysis in the Intensive Care Unit at Secondary Care Hospital in Central Java. The quality of sputum was determined by using a Modification Criteria of Bartlett and a Semi-Quantitative Score. The results of sputum culture with neutrophils count > 10 and bacterial count > 2 per field in Gram stain were considered the presumptive pathogen. Seventy sputum specimens were collected; however, only 58 were selected for further analysis in this study. In sputum specimens with Bartlett score +2 and Semi-Quantitave score 3 or 4, the chest x-ray results of all patients had positive infiltrates (100%). Diagnostics accuracy of the results of clinical microbiologist examination with chest X-ray had a sensitivity of 90%, specificity of 60.71 %, accuracy of 65.5%, a positive predictive value of 61.36%, a negative predictive value of 78.6%. It was concluded that validation of diagnostic microbiology based on gram stain and culture had susceptible and adequately specific results to differentiate between presumptive pathogens from colonization in pneumonia cases.
Peningkatan Pengetahuan tentang Keputihan dan Pemeriksaan Sekret Vagina sebagai Upaya Pencegahan Kejadian Bakterial Vaginosis pada Wanita Usia Produktif Rahayu, Rahayu; Masfiyah, Masfiyah; Soraya, Yulice; Hapsari Putri, Indri; Intisari, Dewi
Indonesian Journal of Community Services Vol 5, No 2 (2023): November 2023
Publisher : LPPM Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijocs.5.2.156-163

Abstract

Mikroflora normal vagina merupakan faktor kesehatan yang penting bagi wanita. Penurunan jumlah Lactobacillus spp berhubungan dengan perubahan flora vagina dan pertumbuhan mikroorganisme patogen sehingga menyebakan infeksi pada vagina. Bakterial Vaginosis merupakan gangguan pada mikoflora vagina dimana secara normal didominasi oleh Lactobacillus spp. Pada studi cross sectional, terdapat hubungan yang signifikan antara bakterial vaginosis dengan banyak infeksi menular seksual termasuk Gonore, infeksi Chlamydia, Trichomoniasis dan HIV. Data pada kelompok pekerja wanita cleaning service di RS Islam Sultan Agung Semarang menunjukkan sebagian besar berusia 20– 40 tahun. Pendidikan terakhir terbanyak adalah SMA (68,9%). Usia pernikahan terbanyak adalah > 5 tahun – 10 tahun (37,9). Sebanyak 48,2 % peserta belum pernah mendapatkan informasi tentang keputihan sebelumnya. Pengetahuan tentang keputihan fisiologis dan patologis belum banyak dimengerti oleh masyarakat khususnya dalam hal ini adalah pekerja cleaning service. Kegiatan yang diusulkan sebagai solusi adalah pemberian penyuluhan tentang keputihan dan pemeriksaan sekret vagina untuk deteksi awal bakterial vaginosis. Hasil dari kegiatan pengabdian masyarakat ini adalah terdapat sebanyak 25 dari 29 peserta (86,2%) mengalami peningkatan pengetahuan tentang keputihan. Dari hasil pemeriksaan sekret vagina didapatkan hasil sebanyak 26 peserta memiliki pH normal (3-4), sedangkan sebanyak 3 peserta memiliki hasil pH > 4,5 dan mengalami bakterial vaginosis. Normal vaginal microflora is an important health factor for women. The decrease in the number of Lactobacillus spp is associated with changes in the vaginal flora and the growth of pathogenic microorganisms that cause vaginal infections. Bacterial Vaginosis is a disorder of the vaginal microflora which is normally dominated by Lactobacillus species. In a cross-sectional study, there was a significant association between bacterial vaginosis and many sexually transmitted infections including Gonorrhea, Chlamydia infection, Trichomoniasis and HIV. Data on the group of cleaning service workers at the Sultan Agung Islamic Hospital in Semarang shows that most are 20–40 years old. Most recent education is high school (68.9%). The most age of marriage is > 5 years – 10 years (37.9). As many as 48.2% of participants had never received information about vaginal discharge before. Knowledge about physiological and pathological leucorrhoea is not widely understood by the public, especially in this case cleaning service workers. Activities proposed as a solution are the provision of counseling about vaginal discharge and examination of vaginal secretions to detect early bacterial vaginosis. The result of this community service activity was that 25 of the 29 participants (86.2%) experienced an increase in knowledge about vaginal discharge. From the results of vaginal secretion examination, it was found that 26 participants had a normal pH (3 -4), while 3 participants had a pH > 4.5 and experienced bacterial vaginosis.
Gambaran Radiografi Toraks Sebagai Prediktor Outcome Pasien COVID-19 Safarini, Bekti; Sutikno, Dria Anggraeny; Intisari, Dewi
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2278

Abstract

COVID-19 (coronavirus disease 2019) is a pulmonary infection disease caused by SARS-CoV-2. Chest radiographic examination of COVID-19 cases performed to make a diagnosis and monitor therapy. Objective: To    evaluated the results of chest radiography examination in COVID-19 cases as a predictor of patient outcome after treatment at the Sultan Agung Islamic Hospital in Semarang. Methods: This research was an observational analytic study with a retrospective design using medical record data from January until December 2021. The results of chest radiographs were analyzed using the Brixia Score system with a maximum score of 18. Outcomes of COVID-19 patients were described as recovered patients or died. Data analysis uses the ROC curve to determine the cut-off point. Results: This study showed that out of 47 patients (43±14 years old), 39 patients (81%) recovered and nine patients died (19%). The levels of leukocytes, D-dimer, Neutrophil-lymphocyte ratio (NLR), and Brixia scores were significantly higher in dead patients (p<0.05). Sensitivity and specificity values predictor of leukocyte count (83%, 61%), D-dimer (83%, 84%), NLR (83%, 82%), and Brixia score (83%, 79%), respectively. Conclusion: Increased levels of leukocytes, D-dimer, NLR, and Brixia Score can be used as a predictor of patient mortality after hospitalization.Keywords: Brixia score, COVID-19, thoracic radiograph
Co-Authors Bekti Safarini, Bekti Hapsari Putri, Indri Hibatullah, M. Adam Masfiyah Masfiyah, Masfiyah Putri, Indri Hapsari Rahayu Rahayu Soraya, Yulice Sutikno, Dria Anggraeny