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All Journal Jurnal Kesehatan Andalas Journal of Midwifery and Health Science of Sultan Agung
Sutikno, Dria Anggraeny
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Health Professions Medicine & Pharmacology Nursing Public Health

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Gambaran Radiografi Toraks Sebagai Prediktor Outcome Pasien COVID-19 Safarini, Bekti; Sutikno, Dria Anggraeny; Intisari, Dewi
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2278

Abstract

COVID-19 (coronavirus disease 2019) is a pulmonary infection disease caused by SARS-CoV-2. Chest radiographic examination of COVID-19 cases performed to make a diagnosis and monitor therapy. Objective: To    evaluated the results of chest radiography examination in COVID-19 cases as a predictor of patient outcome after treatment at the Sultan Agung Islamic Hospital in Semarang. Methods: This research was an observational analytic study with a retrospective design using medical record data from January until December 2021. The results of chest radiographs were analyzed using the Brixia Score system with a maximum score of 18. Outcomes of COVID-19 patients were described as recovered patients or died. Data analysis uses the ROC curve to determine the cut-off point. Results: This study showed that out of 47 patients (43±14 years old), 39 patients (81%) recovered and nine patients died (19%). The levels of leukocytes, D-dimer, Neutrophil-lymphocyte ratio (NLR), and Brixia scores were significantly higher in dead patients (p<0.05). Sensitivity and specificity values predictor of leukocyte count (83%, 61%), D-dimer (83%, 84%), NLR (83%, 82%), and Brixia score (83%, 79%), respectively. Conclusion: Increased levels of leukocytes, D-dimer, NLR, and Brixia Score can be used as a predictor of patient mortality after hospitalization.Keywords: Brixia score, COVID-19, thoracic radiograph
Ultrasonographic Features of Hydatidiform Mole in a 35-Year-Old Woman Treated with Methotrexate: Imaging Findings and Drug-Induced Cutaneous Manifestations Sutikno, Dria Anggraeny
Journal of Midwifery and Health Science of Sultan Agung Vol. 5 No. 1 (2026): JMHSA
Publisher : Sultan Agung Islamic University of Semarang

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Abstract

Hydatidiform mole is a form of gestational trophoblastic disease (GTD) characterized by abnormal proliferation of trophoblastic tissue. It commonly presents with excessive uterine enlargement in early pregnancy and markedly elevated β-hCG  levels. The spectrum of GTD comprises several pathologic entities, that originate from abnormal fertilization that leads to a proliferative process with similarities to the normal trophoblast. These entities include complete and partial hydatidiform moles, which constitutes more than 80% of cases; an invasive mole, which refers to persistent local disease after treatment; and choriocarcinoma, which constitutes 1% to 2% of cases. Early diagnosis and prompt management are crucial to prevent complications. This report describes a case of complete hydatidiform mole in a 35-years-old, in which diagnosis was primarily established through characteristic imaging findings, particularly on pelvic ultrasonography. The patient subsequently underwent methotrexate chemotherapy, with imaging also contributing to treatment monitoring and follow-up assessment. In addition, this report highlights the adverse effects of methotrexate, with particular emphasis on cutaneous manifestations.
Co-Authors Bekti Safarini, Bekti Intisari, Dewi