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All Journal CAUCHY: Jurnal Matematika Murni dan Aplikasi BAREKENG: Jurnal Ilmu Matematika dan Terapan
Damayanti, Erlyana Trie
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Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Energy Engineering Mathematics Mechanical Engineering Physics Transportation

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ANALYSIS AND OPTIMAL CONTROL OF HIV GROWTH MODEL IN THE BODY WITH ANTIRETROVIRAL THERAPY Damayanti, Erlyana Trie; Imron, Chairul
BAREKENG: Jurnal Ilmu Matematika dan Terapan Vol 18 No 2 (2024): BAREKENG: Journal of Mathematics and Its Application
Publisher : PATTIMURA UNIVERSITY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/barekengvol18iss2pp1179-1188

Abstract

Human Immunodeficiency Virus (HIV) is a virus that affects the human immune system. HIV infection causes a decrease in the body's immunity because the virus attacks immune-building cells, especially T-CD4 cells. Currently, there is no treatment that can cure or eliminate HIV, but antiretroviral therapy can be done. This study discusses the growth model of HIV in the body that is given control in an effort to maximize healthy T-CD4 cells. In this model, the infection-free and infected equilibrium points are also discussed and their stability is analyzed. Then the optimal control is solved using the Pontryagin Maximum Principle method and solved numerically using the fourth-order Runge Kutta method. Based on the analysis and simulation results, the system is asymptotically stable around the infection-free equilibrium point and unstable around the infected equilibrium point. Simulation results show that with the control of antiretroviral therapy, the T-CD4 cell population grows significantly which can improve the quality of life of patients. And the growth of HIV in the body can be inhibited until it cannot reproduce itself.
LQR and Fuzzy-PID Control Design on Double Inverted Pendulum Damayanti, Erlyana Trie; Mardlijah, Mardlijah; Rohman Wijaya, Ridho Nur
CAUCHY: Jurnal Matematika Murni dan Aplikasi Vol 9, No 1 (2024): CAUCHY: JURNAL MATEMATIKA MURNI DAN APLIKASI
Publisher : Mathematics Department, Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/ca.v9i1.22070

Abstract

Double inverted pendulum is a non-linear and unstable system. Double inverted pendulum can be stabilized in the upright position by providing control to the system. In this research we compare two types of controllers namely Linear Quadratic Regulator (LQR) and Fuzzy-PID. The objective is to determine the control strategy that provides better performance on the position of the cart and pendulum angle. We modelled the system which is then linearized and given control. From the simulation results, it is proven that LQR and Fuzzy-PID controllers have been successfully designed to stabilize the double inverted pendulum. However, when given a disturbance in the form of noise step, the LQR controller has not been able to achieve the desired reference for up to 20 seconds. In another hand, the Fuzzy-PID controller is able to achieve the desired reference after 8 seconds. Therefore, it can be concluded that the Fuzzy-PID controller when applied to the Double Inverted pendulum system has better performance than the LQR controller.
Co-Authors Chairul Imron, Chairul Mardlijah - Rohman Wijaya, Ridho Nur