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All Journal International Journal of Health, Economics, and Social Sciences (IJHESS) Jurnal Medika Nusantara Vitamin: Jurnal Ilmu Kesehatan Umum Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Anik Eko Novitasari
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Economics, Econometrics & Finance Health Professions Nursing Public Health Social Sciences

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Hubungan Jumlah Trombosit Dan D-Dimer Pasien Covid-19 Di RSI Fatimah Banyuwangi Rosidah Rosidah; Riski Maulana; Anik Eko Novitasari; Lina Madyastuti
Jurnal Medika Nusantara Vol. 2 No. 1 (2024): Februari : Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v2i1.917

Abstract

According to the Indonesian Ministry of Health (2020), Corona virus (CoV) is a large family of viruses that can cause illness ranging from mild, moderate to severe symptoms. Corona virus is zoonotic (transmitted between animals and humans). Research says that SARS-CoV is transmitted from civet cats (civetcats) to humans and MERS-CoV from camels to humans. Platelets are an important component in the hemostatic response which are closely related to other hemostatic components (NugrahaGilang, 2017). Platelets were obtained from the cytoplasm of megakaryocytes (80-150 m in size). D-dimer is a fibrin degradation product formed during the degradation of blood clots by fibrinolysis. Elevated D-dimer in the blood is a marker of suspected thrombosis. Platelet examination using the Direct method. Analysis of platelet levels with an average of 379.231.6 cells/permicroliter of blood. The purpose of this study was to determine the relationship between platelet levels and D-dimer in Covid-19 patients. The conclusion of this study is that there is a relationship between the results of the examination of platelet levels with D-dimer levels, if the platelet levels increase, the D-dimer levels increase.
Effect of Extraction and Centrifugation on Caffeine Levels in Urine of Robusta Coffee Drinkers Using the Method of Uv-Vis Spectrophotometry Anik Eko Novitasari; Nikmatul Fitriyah
International Journal of Health, Economics, and Social Sciences (IJHESS) Vol. 7 No. 1: January 2025
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/ijhess.v7i1.6844

Abstract

Caffeine is a heterocyclic alkaloid compound in the methylxanthine group that has a bitter taste that works as a mild diuretic and psychoactive stimulant. These compounds are naturally found in more than 60 types of plants, including coffee plants. Coffee is known as a drink that has a high enough caffeine content. Caffeine content in robusta coffee raw beans is higher than Arabica coffee which is only about 1.2%. The content of caffeine in the body is broken down in the liver by the enzyme cytochrome P-450 into metabolic 3-dimethylxanthin which is then excreted in the urine. Analysis of caffeine in urine was carried out quantitatively by means of UV-Vis Spectrophotometry. The analysis process is carried out by extraction and centrifugation. Based on this study, a study was conducted to determine the differences in extraction and centrifugation methods on caffeine levels in the urine of robusta coffee drinkers using the UV-Vis spectrophotometric method. The results were analyzed using the Paired T-Test through SPSS. The results showed that there was significant difference in the levels of caffeine extracted and centrifuged in the urine of robusta coffee drinkers using the UV-Vis Spectrophotometry method. The caffeine content in the urine sample was obtained with the lowest extraction at 29.60 ppm and the highest caffeine content at 50.18 ppm. Meanwhile, in urine samples by centrifugation, the lowest caffeine content was 35.71 ppm and the highest caffeine content was 50.45 ppm.
Analysis Of Mefenamic Acid Residue In Urine Of Herbal Madicine For Aches and Pains Consumers Using Ultraviolet-Visible Spectrophotometry Method Anik Eko Novitasari; Ria Ratna Amelia
International Journal of Health, Economics, and Social Sciences (IJHESS) Vol. 7 No. 3: July 2025
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/ijhess.v7i3.8922

Abstract

Mefenamic acid is the chemical drug that has been added to herbal medicine. With the presence of these chemical additives that are not controlled will be harmful to society. So it is necessary to determine the presence of residual mefenamic acid content in the urine of consumption of herbal medicine aches and pains by ultraviolet-visible spectrophotometry. The sampling technique in this study used the Non-Probability Sampling technique with a total of 30 urine samples consuming stiff rheumatic herbs in Desa Panggang, Glagah, Lamongan. Based on the research that has been done, it was found that 30 urine samples of consuming herbal medicine A, B, C, and D were positive for the chemical mefenamic acid with the highest level of 7.16% and the lowest level of 2.17%. From the results of the analysis of the normality test and homogeneity test, it is obtained that the data are normally distributed and homogeneous. Based on the results of the Independent T Test, the value of Sig. (2-tailed) of 0.000 <0.05, which means that there is a mefenamic acid content in the urine of those who consume herbal medicine aches and pains.
Gambaran Residu Paparan Formalin pada Sampel Plasma Darah Karyawan Instalasi Hemodialisis Rumah Sakit Anik Eko Novitasari; Rezki Febianti
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 2 No. 1 (2024): January : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v2i1.130

Abstract

Hemodialysis is one of the installations in the hospital that handles blood washing therapy, by removing excess waste or harmful compounds, through a semi-permeable membrane which is carried out to replace kidney function that is no longer functioning properly. Hemodialysis is given to patients with a diagnosis of acute renal failure, terminal renal failure and patients who have severe poisoning with certain drugs. The research design was carried out descriptively. The aim of this research was to determine whether there was formalin exposure to hemodialysis workers or nurses when reusing or cleaning hemodialysis equipment, using a qualitative test. In this research, the results were obtained from 15 blood plasma samples, namely 6 positive formalin blood samples, with Schiff, Tollens, KMnO4 and Fehling reagents. It is known from the table of analysis results of qualitative test of formalin exposure on hemodialysis workers in one of the East Java Hospitals. For further research, it is hoped that quantitative tests will be carried out in determining the level of formalin in the blood using the instrument.
Variasi Konsentrasi Fase Gerak pada Analisis Hidrokuinon dalam Sabun Pemutih dengan Metode Kromatografi Kertas Anik Eko Novitasari; Lailatul Fitriyah; Rosidah Rosidah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i4.637

Abstract

Hydroquinone is a compound that is often used in skin whitening beauty products. According to BPOM 2007, the use of hydroquinone at levels above 2% can cause skin disorders, namely hyperpigmentation which can lead to skin cancer. This research was conducted to qualitatively analyze the hydroquinone compound found in skin whitening soap which does not have a BPOM number. The aim of this research is to determine the presence of hydroquinone compounds contained in skin whitening soap samples and to determine the differences in Rf values ​​resulting from the comparison of the concentrations of the mobile phase used. Qualitative analysis was carried out by calculating the Rf value of paper chromatography using a comparison of variations in mobile phase concentration, namely 50% ethanol: chloroform (1: 1) and 90% ethanol: chloroform (1: 1). The analysis results show that the standard Rf value of hydroquinone from the eluent of 50% ethanol and chloroform is 0.46, where this Rf value is the same as the Rf value from sample number 5, namely 0.46. Meanwhile, the Rf value using 90% ethanol and chloroform eluents in sample No. 5 is 0.67, which is not the same as the standard Rf value, namely 0.56. Of the whitening soap samples, 1 sample showed a positive result containing hydroquinone.
Co-Authors LAILATUL FITRIYAH Lina Madyastuti NIKMATUL FITRIYAH Rezki Febianti Ria Ratna Amelia Riski Maulana Rosidah Rosidah