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All Journal Journal of Tropical Biodiversity and Biotechnology Jurnal Biologi Tropis
Fadhilah, Diana
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Immunology & microbiology

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Utilisation of Snails for Wound Healing: A Review Fadhilah, Diana; Santoso, Putra; Maliza, Rita
Journal of Tropical Biodiversity and Biotechnology Vol 9, No 3 (2024): September
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jtbb.90236

Abstract

Snails exhibit remarkable adaptability, allowing them to flourish in diverse environmental conditions and resulting in thriving populations in specific regions. This abundance has led communities to harness snails for various purposes, including their use as animal feed, daily dietary source, and in traditional wound-healing practices with historical roots. The primary objective of this systematic review is to identify the snail species commonly employed in wound healing and evaluate the bioactivity of compounds derived from different snail species. This review was conducted using literature review method, drawing from international databases such as Scopus, and encompassed publications from 2013 to 2023. A total of 22 articles met the inclusion and exclusion criteria. Snail body parts that have been explored for wound-healing purposes include both the body and the shell, along with snail secretions, particularly their mucus. Various methods have been employed to extract mucus, involving manual stimulation of the snail's body, spraying with a saline solution (NaCl), application of electric shock, and the use of ozone gas through nebulisation. Prominent snail species found to be beneficial for wound healing include Achatina fulica, Helix aspersa, Eobania desertorum, Helix lucurus, Cornu bistrialis, Theba pisana, and Megalobulimus lopesi. These snail species demonstrate potential applications in the treatment of burns, excision wounds, incision wounds, and diabetic ulcers. Key compounds within snail secretions encompass mucopolysaccharides, polyphenols, peptides, and glycosaminoglycans. These compounds exert significant effects on haemostasis, inflammation control, cellular proliferation, and re-epithelialisation, significantly contributing to the wound healing process. 
Physical Quality and Organoleptic Testing of Golden Apple Snail Pomacea canaliculata) Mucus Gel as a Burn Treatment Fadhilah, Diana; Nadjmir, Mikail; Adilla, Ardis Trianita; Santoso, Putra; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8023

Abstract

Golden Apple Snail (Pomacea canaliculata) secretion has traditionally been used for wound healing due to its high protein content, which promotes cell regeneration and inhibits inflammation. This study aims to utilize this secretion to formulate a topical gel for burn treatment, providing a controlled use for the abundant, invasive species in agricultural areas. Gel formulations with varying secretion concentrations (10%, 15%, and 20%) were evaluated for organoleptic properties, homogeneity, pH, adhesion, spreadability, and viscosity. Results indicated that all formulations were homogeneous and had pH values within the acceptable range (4.5-6.5). The 15% secretion gel showed the highest user acceptance and optimal balance between spreadability and adhesion, but all formulations had higher than standard viscosity and lower spreadability. Adjusting carbopol concentration is recommended to improve the gel's physical properties. The 15% formulation is the most promising for effective topical application.
Co-Authors Adilla, Ardis Trianita Maliza, Rita Nadjmir, Mikail Putra Santoso