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All Journal Jurnal Kartika Kimia
Fadlilah, Gina
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education

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Aktivitas Antioksidan Senyawa 6-propil-5,6-dihidro-2h-piran-2-on dari Jamur Endofit Fusarium oxysporum Akar Kalanchoe millotii Purbaya, Sari; Fadlilah, Gina; Aprina, Lutfia Silva; Agustini, Dewi Meliati; Aisyah, Lilis Siti; Supratman, Unang; Yun, Yenny Febriani
Jurnal Kartika Kimia Vol 6 No 2 (2023): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v6i2.211

Abstract

Kalanchoe millotii or cocor bebek is a succulent plant that is rich in secondary metabolites and utilized as a traditional medicine. The exploration of secondary metabolite content and bioactivity of Fusarium oxysporum, an endophytic fungus from the roots of K. millotii, is of interest. The compound 6-propyl-5,6-dihydro-2H-piran-2-on was successfully isolated from the ethyl acetate extract of F. oxysporum through various chromatographic methods. Structure elucidation of compound 6-propyl-5,6-dihydro-2H-piran-2-on based on NMR (1H-NMR, 13C-NMR, HMQC, HMBC, COSY), UV, and FTIR spectra. The antioxidant activity of the ethyl acetate extract of F. oxysporum and its isolates was determined based on the DPPH (2,2 diphenyl-1-picrylhydrazyl) method. The isolate showed moderate antioxidant activity with IC50 of 153.39 ppm.
Co-Authors Agustini, Dewi Meliati Aprina, Lutfia Silva Lilis Siti Aisyah, Lilis Siti Purbaya, Sari Unang Supratman Yenny Febriani Yun, Yenny Febriani