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All Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) The Journal of Society Medicine (JSOCMED)
Putra, Muhammad Hafiz Mahruzza
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Cardiometabolic Risk Assessment through Comprehensive Screening for Early Detection Andra, Cut Aryfa; Hasan, Refli; Khairul, Andi; Tamba, Ratna Mariana; Putra, Muhammad Hafiz Mahruzza
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 3 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i3.12818

Abstract

Background: The development of cardiovascular disease (CVD) is influenced by many risk factors, such as tobacco use, an unhealthy diet, and physical inactivity, that could result in obesity, hypertension, dyslipidemia, and diabetes mellitus. Continuing exposure to these risk factors can be prevented by routine screening for populations without any clinical symptoms. This study was conducted to obtain data on cardiometabolic profiles of people who participated in the Community Service Program of the Department of Cardiology and Vascular Disease, University of Sumatera Utara. Method: This research was a descriptive study with a cross-sectional research design. The study aims to screen for the cardiometabolic profile in the people of Tebing Tinggi City.  Cardiovascular risk factors were obtained from interviewing the participants and on-the-spot examination with validated measurement tools. All data were processed and analyzed statistically using SPSS ver.26. Categorical variables are presented with frequency (n) and percentage (%). Numeric variables are presented with mean and standard deviation (SD) values for normally distributed data. As for the normal non-distributed data numerical variables are presented with the middle value (median) and the interquartile range. Results: All subjects in this study (n= 102) are 39 male and 63 female. Most participants were in the 4th to 5th decade, with normal heart rates and normal sinus rhythm. Most female participants had a low risk for obstructive sleep apnea (OSA) and the male had intermediate risk. Most participants had normal random blood sugar and total cholesterol but mostly had obesity. Near 20-30% of participants were grade I and II systolic hypertensives but normally had diastolic blood pressure. Conclusion: In this study, most of the cardiometabolic risks of patients in the Community Service program were obesity, followed by hypertension.
Relationship between Coronary Artery Calcium Score (CACS) and Diastolic Dysfunction in Patients with Stable Coronary Heart Disease at Adam Malik General Hospital Medan Putra, Muhammad Hafiz Mahruzza; Hasan, Refli; Sitepu, Andika; Hasan, Harris; Ketaren, Andre Pasha; Andra, Cut Aryfa; Raynaldo, Abdul Halim; Ilyas, Kamal Kharrazi
Journal of Society Medicine Vol. 4 No. 6 (2025): June
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i6.221

Abstract

Introduction: Coronary artery calcium score (CACS) is a specific indicator of coronary atherosclerosis that plays a role in assessing the degree of calcification in atherosclerosis. Diastolic function is the first aspect of cardiac function to be impaired in ischemic heart disease. This study aims to determine the relationship between calcium scoring and diastolic dysfunction. Methods: This analytical observational study with cross-sectional design evaluated the relationship between coronary artery calcium score (CACS) and left ventricular diastolic function in patients with stable CAD. Data were collected retrospectively from medical records at RSUP H. Adam Malik Medan during Nov 2023-Nov 2024. CACS was assessed using coronary CT scan, while left ventricular diastolic function was measured by echocardiography. Data analysis used chi-square test, Mann-Whitney U test, and ROC curve analysis to evaluate CACS threshold in predicting diastolic dysfunction. Results: Among 158 analyzed samples, 113 patients had diastolic dysfunction. A calcium score ≥100 was found in 46.2% of patients, showing 1.318 times higher risk of diastolic dysfunction versus those with scores <100 (p = 0.006; 95% CI 1.083–1.605). ROC analysis showed CACS had moderate predictive ability for diastolic dysfunction with AUC of 0.647 (p = 0.004). A calcium score threshold of 45 had 65.5% sensitivity and 62.2% specificity in detecting diastolic dysfunction. Type 2 diabetes mellitus, urea, and creatinine levels were also significantly associated with diastolic dysfunction (p < 0.05). Conclusion: Calcium score shows a significant relationship with diastolic dysfunction in stable CAD patients and can predict diastolic dysfunction in patients undergoing coronary CT scan.
Co-Authors Andra, Cut Aryfa Hasan, Harris Hasan, Refli Ilyas, Kamal Kharrazi Ketaren, Andre Pasha Khairul, Andi Raynaldo, Abdul Halim Sitepu, Andika Tamba, Ratna Mariana