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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Farmasi Sains dan Komunitas Jurnal Sinergitas PkM & CSR Jurnal Pengabdian Kesehatan Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK)
Handika Immanuel
Faculty Of Pharmacy, Universitas Sanata Dharma
Economics, Econometrics & Finance Education Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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PENYULUHAN PENCEGAHAN PENULARAN COVID-19 KEPADA GURU DAN ORANG TUA MURID DI PAUD-TK BINTANG KECIL, KABUPATEN BEKASI [EDUCATION ON PREVENTION OF COVID-19 TRANSMISSION TO TEACHERS AND PARENTS AT BINTANG KECIL KINDERGARTEN, BEKASI REGENCY] Pangeran Andareas; Dela Rosa; Anastasia Setyopuspito Pramitaningastuti; Handika Immanuel; Ernestine Arianditha Pranasti; Anugerah Moses Matthew; Cerissa Cerissa; Chintya Eirene Hadi; Angela Puspita Sari; Christian Jose Andreas
Jurnal Sinergitas PKM & CSR Vol 6, No 1 (2022): APRIL
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/jspc.v6i1.5255

Abstract

Community Service (CS) is one part of Tridarma of higher education in Indonesia that correlates the world of education to the community. CS activities aim to actualize knowledge and skills possessed by universities to the community in the hope that it will solve various problems in the community and improve the welfare of the community. The Covid-19 pandemic is a health problem that is currently being faced by the Indonesian people, especially in crowded areas such as the school environment. The real impact of the Covid-19 pandemic is a decline in health levels that causes death in the community. One of these conditions is suspected to be due to a lack of education to the public about preventing the transmission of Covid-19. Based on these problems, CS activities were carried out in the form of online counseling on preventing the transmission of Covid-19 to teachers and parents at Bintang Kecil Kindergarten, Bekasi Regency. CS data was obtained by using a Pre-Experimental Design (One Group Pre-Test Post-Test) approach using a quiz instrument (goggle form). The result of pre-test and posttest showed an increase in the knowledge of teachers and parents in the Kindergarten of Bintang Kecil, Bekasi Regency by 13,1%. BAHASA INDONESIA ABSTRACT: Pengabdian kepada Masyarakat (PkM) merupakan salah satu bagian dari Tridharma perguruan tinggi di Indonesia yang mengkorelasikan antara dunia pendidikan dengan masyarakat. Kegiatan PkM bertujuan untuk mengaktualisasikan ilmu pengetahuan dan keterampilan yang dimiliki perguruan tinggi kepada masyarakat dengan harapan akan menyelesaikan berbagai permasalahan di masyarakat serta meningkatkan kesejahteraan masyarakat. Pandemik Covid-19 merupakan permasalahan kesehatan yang saat ini sedang dihadapi oleh masyarakat Indonesia, terutama pada area yang padat seperti lingkungan sekolah. Dampak nyata dari pandemik Covid-19 adalah terjadinya penurunan tingkat kesehatan hingga menyebabkan kematian di masyarakat. Kondisi demikian salah satunya diduga karena kurangnya edukasi kepada masyarakat mengenai pencegahan penularan Covid-19. Berdasarkan permasalahan tersebut, sehingga dilakukan kegiatan PkM dalam bentuk penyuluhan secara daring mengenai pencegahan penularan Covid-19 kepada guru serta orang tua murid di PAUD-TK Bintang Kecil, Kabupaten Bekasi. Data kegiatan PkM diperoleh dengan pendekatan Pre-Experimental Design (One Group Pre-Test Post-Tes) menggunakan instrument kuis (google form) berisi 10 pertanyaan.  Hasil pre-test dan post-test menunjukkan adanya peningkatan pengetahuan guru dan orang tua murid di PAUD-TK Bintang Kecil, Kabupaten Bekasi sebesar 13,1%. 
Kajian Rute Alternatif Pemberian Liraglutide dalam Penanganan Diabetes dan Obesitas Immanuel, Handika
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 20, No 2 (2023)
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v20i2.9299

Abstract

Liraglutide adalah sebuah obat peptida yang digunakan untuk menangani diabetes tipe 2 dan obesitas. Liraglutide diberikan secara injeksi subkutan setiap harinya. Rute injeksi subkutan dapat menyebabkan rasa sakit dan ketidaknyamanan bagi beberapa pasien. Oleh sebab itu, penting untuk meninjau keefektifan dan keamanan rute alternatif ini untuk memastikan bahwa pasien memiliki akses ke pilihan pengobatan yang paling tepat dan nyaman. Rute pemberian alternatif seperti oral dan subkutan yang diperlama pelepasan obatnya, serta topikal, mulai dikembangkan. Artikel review deskriptif ini dibuat dengan metode penelaahan pustaka menggunakan kriteria inklusi dan eksklusi. Beberapa penelitian telah dilakukan untuk mengevaluasi efikasi dan keamanan liraglutide yang diberikan melalui rute alternatif seperti oral dan topikal. Liraglutide yang diberikan melalui rute oral menggunakan teknologi enkapsulasi telah menunjukkan manfaat yang serupa dengan liraglutide yang diberikan melalui injeksi subkutan, ditandai dengan adanya penurunan kadar glukosa darah serta penurunan berat badan yang sebanding. Pemberian liraglutide yang telah dienkapsulasikan melalui injeksi subkutan juga telah diketahui dapat memberikan durasi efek farmakologis yang lebih panjang, sehingga meminimalkan frekuensi pemakaian liraglutide.
Na-CMC and glycerine optimization in Binahong leaf extract (Anredera cordifolia) liposome gel and its burn wound healing activity Immanuel, Handika; Branitasandini, Regina Epiphania Adhika; Branitasandini, Adhika; Arpan, Verdynant Augusto; Pebrianty, Sahara; Kerenhapukh, Miracle; Wardhani, Kresentia Ayu Kusuma; Yuliani, Sri Hartati
Pharmaciana Vol. 15 No. 1 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i1.30112

Abstract

Burns represent a critical global health issue, contributing to considerable morbidity and mortality rates, particularly within the Southeast Asian region. The administration of appropriate burn therapy is essential to prevent infections and promote effective wound healing. The binahong leaf (Anredera cordifolia) represents a highly promising natural substance for burn therapy, attributed to its ursolic acid content, which is acknowledged for its wound healing properties. However, the limitation caused by its limited solubility and bioavailibility requires the use of nanoparticle technology, such as liposomes, to enhance its efficacy. The aim of this research was to determine an optimal formulation of gel containing liposome-encapsulated binahong leaf extract, with the goal of promoting burn wound healing and examining its in vivo wound healing activity. Histological analysis was employed to provide additional insights into the activity of the gel. The formulation was assessed through a factorial design, exploring various amounts of Na-CMC utilized as a gelling agent alongside glycerine employed as a humectant. The results were subsequently analyzed utilizing Design Expert v13 software. The gel’s viscosity, spreadability, and uniformity were assessed. Na-CMC increased viscosity while reducing spreadability, whereas glycerine had the opposite effect. The optimal formulation contained 2.78–4 g Na-CMC and 5–10 g glycerine. Statistical validation confirmed the model's accuracy. In vivo studies demonstrated that liposomal binahong gel significantly accelerated burn wound healing compared to controls. The results suggest that 10% binahong liposomal gel is a promising alternative for burn treatment.
Peningkatan Pengetahuan Tentang Gizi dan Stunting di Wonosari, Gunungkidul, DIY: Improving Knowledge of Nutrition and Stunting in Wonosari, Gunungkidul, DIY Virginia, Dita Maria; Wakitha, Stephanus Satria Wira; Immanuel, Handika; Rohmahtika, Amanda; Travita, Anggi Silva; Djunaedi, Jeniffer Kalyana Paramita; Jannah, Widyatul; Pero, Veronika Giuliany
Jurnal Pengabdian Kepada Masyarakat: Kesehatan Vol. 5 No. 1 (2025): Maret
Publisher : Sekolah Tinggi Ilmu Kesehatan Notokusumo Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstrak: Stunting merupakan problem kesehatan masyarakat yang belum dapat dituntaskan. Stunting dipengaruhi oleh minimnya pengetahuan mengenai stunting dan gizi yang baik untuk pencegahan stunting. Program pengabdian bertujuan untuk  pemahaman masyarakat tentang pentingnya asupan gizi seimbang dan suplementasi vitamin dalam mencegah stunting. Angka stunting di Desa Baleharjo masih tinggi. Metode kegiatan pengabdian berupa participatory action service karena melibatkan Puskesmas Wonosari II dengan wilayah kerja Desa Baleharjo, Wonosari. Kegiatan berupa penyuluhan kepada kader dan ibu yang memiliki anak balita serta terdapat kegiatan pendampingan untuk ibu dan anak. Hasil penyuluhan menunjukkan pengetahuan mengenai (1) hal yang harus dilakukan pada periode 1000 HPK (p-value=0,00) dan (2) nutrisi terbaik pada MPASI untuk mencegah stunting (p-value=0,02), meningkat secara signifikan. Pengetahuan lain tidak terdapat peningkatan secara signifikan. Saran untuk pengabdian selanjutnya perlu mempertimbangkan pendampingan secara langsung dari waktu ke waktu dengan meningkatkan peran kader. Kegiatan pengabdian selanjutnya juga perlu mempertimbangkan pengukuran terhadap luaran utama berupa penurunan angka stunting ataupun perubahan perilaku.   Abstract: Stunting is a public health problem that has not been resolved. Stunting is influenced by the lack of knowledge about stunting and good nutrition to prevent stunting. The community service program aimed to provide community knowledge related to the importance of balanced nutritional intake and vitamin supplementation in preventing stunting. The stunting rate in Baleharjo Village is still high. The community service activity method was participatory action service because we involved the Wonosari II Health Center which their working area is ??Baleharjo Village, Wonosari. Activities included counseling for cadres and mothers who have a children aged below 5 years old, and there were mentoring activities for mothers and children. The results of the counseling showed that knowledge about (1) things should to do in the 1000 FDB period (p-value = 0.00) and (2) the best nutrition in MPASI to prevent stunting (p-value = 0.02), has increased significantly. Other knowledge did not increase significantly. Suggestions for further community service need to consider direct mentoring from time to time by increasing the role of cadres. It should consider the measurement of primary outcomes such as the reduction in the number of stunted children or behavioral changes.
Pelatihan Pemanfaatan Bahan Alam Dalam Sediaan Perawatan Kulit Putri, Dina Christin Ayuning; Yuliani, Sri Hartati; Dwiastuti, Rini; Immanuel, Handika
Jurnal Pengabdian Kesehatan Vol 8, No 3 (2025): Jurnal Pengabdian Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/jpk.v8i3.402

Abstract

Saat ini, tren penggunaan sediaan perawatan kulit (skin care) semakin meningkat. Pentingnya penggunaan sediaan perawatan kulit perlu untuk dipahami oleh remaja-remaja. Indonesia sebagai salah satu negara dengan sumber daya alam yang tinggi juga berpotensi dalam menghasilkan sediaan perawatan kulit berbhaan alam. Kegiatan pengabdian ini bertujuan untuk meningkatkan pemahaman remaja tentang pemanfaatan bahan alam dalam sediaan perawatan kulit. Kegiatan pengabdian dilakukan dengan pemberian materi berupa presentasi dan pemutaran video tutorial pembuatan body scrub dari bahan alam. Tingkat pemahaman peserta diuji melalui pretes dan postes. Hasil tes diuji dengan uji T 1 arah untuk sampel berpasangan. Kegiatan terlaksana dengan baik. Jumlah peserta yang hadir adalah sebanyak 88 orang siswa-siswi sekolah menengah dan mahasiswa-mahasiswi. Paparan materi dapat diterima dengan baik dibuktikan dengan meningkatnya rerata nilai pretest dan post test. Hasil uji T juga menunjukkan adanya perbedaan signifikan antara kedua pengujian tersebut, sehingga dapat disimpulkan bahwa peserta mengalami peningkatan pemanfaatan bahan alam dalam sediaan perawatan kulit.
Preparation and Characterization of Binahong (Anredera cordifolia) Leaf Extract Transfersome Wound-Healing Gel Immanuel, Handika; Yuliani, Sri Hartati; Dwiastuti, Rini; Nugraha, Alvin Arya; Limianty, Angela; Annabel, Evangeline Keisha; Lu, Felisha; Lestari, Fajar Sri; Branitasandini, Regina Epiphania
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007311

Abstract

Burn injuries are a significant global health concern due to their profound impact on morbidity and mortality rates. Immediate medical care is essential given the potential for bacterial infections to complicated burn injuries. Binahong leaves (Anredera cordifolia (Ten.) Steenis) contain vitexin compounds that demonstrate wound healing and antibacterial potential. However, vitexin has low solubility, prompting the use of ethanol for extraction and the introduction of nanoparticle technology to enhance solubility, namely transfersomes. The present study explored the development of a gel using binahong extract transfersomes with the composition of carbopol 940 and Na-CMC to determine the effect of carbopol 940, Na-CMC, and the interaction of the two on the gel’s physical properties and stability as well as obtain the optimum composition of the two. This study demonstrates positive results in terms of gel physical properties, including pH, spreadability, and viscosity. A Factorial design method is used for optimization. The results showed that Na-CMC had the most effect on increasing viscosity, while carbopol 940 had the most effect on reducing spreadability. The optimal formula obtained in this research was to use 0.653 grams of Na-CMC and 4.391 grams of Carbopol as gelling agents. 
Co-Authors Angela Puspita Sari Annabel, Evangeline Keisha Anugerah Moses Matthew Arpan, Verdynant Augusto Branitasandini, Adhika Branitasandini, Regina Epiphania Branitasandini, Regina Epiphania Adhika Cerissa Cerissa Chintya Eirene Hadi Christian Jose Andreas Dela Rosa Dina Christin Ayuning Putri Dita Maria Virginia Djunaedi, Jeniffer Kalyana Paramita Ernestine Arianditha Pranasti Jannah, Widyatul Kerenhapukh, Miracle Lestari, Fajar Sri Limianty, Angela Lu, Felisha Nugraha, Alvin Arya Pangeran Andareas Pebrianty, Sahara Pero, Veronika Giuliany Pramitaningastuti, Anastasia Setyopuspito Rini Dwiastuti Rohmahtika, Amanda Sri Hartati Yuliani Travita, Anggi Silva Wakitha, Stephanus Satria Wira Wardhani, Kresentia Ayu Kusuma