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The Influence of Intant Massage to Weight Gains in Low Birth Weight Infant (LBW) : A Systematic Review Atika; Djuari, Lilik; Manaf, Hafizh Al Ghifari; Bachtiar, Daffa Ardhi; Sabrina, Annisa Maya; Ismahendra, Naufal Agus; Soediono, Mochammad Ridhwan; Yuliana, Sitti Khofifah; Razaan, Muhammad Farras; Karim, Yustika Ayoustira
Journal of Community Medicine and Public Health Research Vol. 5 No. 1 (2024): Journal Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jcmphr.v5i1.48642

Abstract

Growth and development is a significant phase that cannot be replicated, underscoring the need for meticulous attention, particularly for those born with low birth weight (LBW). LBW can be stimulated using infant massage. This research aimed to evaluate the impact of infant massage on weight gain among LBW infants. This is a systematic review using PICOS framework, investigating studies from 2018 to 2023 in databases including Cochrane, PubMed, ScienceDirect, and Scopus. The inclusion criteria involved full-text access and the keywords low birth weight, weight gain, and massage. The initial search yielded 1913 literature, which were screened based on publication year and type, resulting in 122 articles. After being examined, 119 articles were excluded due to duplication, using non-English language, involving non-LBW, different outcomes, and non-RCT, leaving three articles. The assessment of literature quality was conducted using the JBI Critical Appraisal Checklist for Systematic Reviews and Research Syntheses. The results of outcome measurements and group comparisons across the three studies exhibited congruence. In conclusion, the finding indicated that infants who underwent massage intervention exhibited weight gain, as did those who did not undergo such intervention. Furthermore, infants who received massage intervention experienced a more pronounced increase in weight compared to their counterparts who did not undergo massage intervention.
Role of Liquid Biopsy as a Future Approach to Early Diagnosis and Management of Colorectal Cancer Danardono, Edwin; Soediono, Mochammad Ridhwan; Amiruddin, Muhammad Tidar Abiyu
Indonesian Journal of Cancer Vol 19, No 3 (2025): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i3.1319

Abstract

Colorectal cancer (CRC) is a major global health challenge, ranking as the third most prevalent cancer worldwide. Traditional tumor biopsies are invasive and limited by issues such as tumor heterogeneity and the inability to perform repeated sampling. Liquid biopsy, a non-invasive diagnostic approach that analyzes biomarkers in bodily fluids like blood, offers an innovative solution to these challenges. By detecting circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), exosomes, and tumor-educated platelets (TEPs), liquid biopsy allows for real-time tumor monitoring, early cancer detection, and personalized treatment strategies. This review explores the clinical applications of liquid biopsy in CRC, highlighting its potential for early detection, monitoring treatment response, and guiding customized therapies. Key biomarkers such as CEA, ctDNA, CTCs, and exosomal miRNAs offer insights into tumor dynamics and prognosis. While liquid biopsy shows promise for broad clinical use, challenges remain in standardizing methodologies and validating its efficacy through large-scale trials. Advances in technology and improved biomarker discovery are expected to enhance the accuracy and utility of liquid biopsy, making it a pivotal tool in CRC management and beyond.
The effect of date fruit consumption on delivery outcomes: A systematic review Kharizmatika; Soediono, Mochammad Ridhwan
Majalah Obstetri & Ginekologi Vol. 34 No. 1 (2026): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V34I12026.61-69

Abstract

HIGHLIGHTS Consuming date fruit in late pregnancy may enhance labor outcomes by reducing labor duration, speeding up cervical dilation, and decreasing the need for induction. Healthcare providers might recommend it as a natural dietary intervention, while further research should standardize protocols and determine optimal dosages.   ABSTRACT Objective: This systematic review examines the impact of date fruit consumption during pregnancy on labor and delivery outcomes. Materials and Methods: A systematic search was carried out utilizing PubMed, Cochrane Library, and ScienceDirect databases to identify systematic reviews and meta-analyses published within the last five years. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria were adhered to in order to identify studies and extract data. Quality evaluation was carried out utilizing the AMSTAR tool to ensure methodological rigor. Results: Among 3,528 initial records, 255 articles met eligibility criteria, with 4 systematic reviews included for analysis. Date fruit consumption was associated with shortened first stage of labor (pooled effect size: -50.09 to -76.16 minutes), reduced second stage duration (pooled effect size: -7.7 to -15.05 minutes), accelerated cervical dilatation (pooled effect size: 0.94 to 1.15 cm), and decreased gestation duration (pooled effect size: -0.30 weeks to -1.97 days). Improved Bishop score (MD/WMD: 2.45 to 2.47) and decreased labor induction frequency (RR: 0.48 to 0.6) were also observed. Heterogeneity in outcomes suggests variable effects across studies. Conclusion: Date fruit consumption in late pregnancy shows potential benefits for labor outcomes, including shorter duration of labor stages, accelerated cervical dilation, and reduced need for labor induction. Healthcare providers may consider recommending date fruit as a natural dietary intervention to enhance maternal and neonatal health during childbirth. Further research should standardize protocols, explore optimal dosages, and elucidate mechanisms to strengthen evidence-based recommendations.