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The Influence of Intant Massage to Weight Gains in Low Birth Weight Infant (LBW) : A Systematic Review Atika; Djuari, Lilik; Manaf, Hafizh Al Ghifari; Bachtiar, Daffa Ardhi; Sabrina, Annisa Maya; Ismahendra, Naufal Agus; Soediono, Mochammad Ridhwan; Yuliana, Sitti Khofifah; Razaan, Muhammad Farras; Karim, Yustika Ayoustira
Journal of Community Medicine and Public Health Research Vol. 5 No. 1 (2024): Journal Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jcmphr.v5i1.48642

Abstract

Growth and development is a significant phase that cannot be replicated, underscoring the need for meticulous attention, particularly for those born with low birth weight (LBW). LBW can be stimulated using infant massage. This research aimed to evaluate the impact of infant massage on weight gain among LBW infants. This is a systematic review using PICOS framework, investigating studies from 2018 to 2023 in databases including Cochrane, PubMed, ScienceDirect, and Scopus. The inclusion criteria involved full-text access and the keywords low birth weight, weight gain, and massage. The initial search yielded 1913 literature, which were screened based on publication year and type, resulting in 122 articles. After being examined, 119 articles were excluded due to duplication, using non-English language, involving non-LBW, different outcomes, and non-RCT, leaving three articles. The assessment of literature quality was conducted using the JBI Critical Appraisal Checklist for Systematic Reviews and Research Syntheses. The results of outcome measurements and group comparisons across the three studies exhibited congruence. In conclusion, the finding indicated that infants who underwent massage intervention exhibited weight gain, as did those who did not undergo such intervention. Furthermore, infants who received massage intervention experienced a more pronounced increase in weight compared to their counterparts who did not undergo massage intervention.
Role of Liquid Biopsy as a Future Approach to Early Diagnosis and Management of Colorectal Cancer Danardono, Edwin; Soediono, Mochammad Ridhwan; Amiruddin, Muhammad Tidar Abiyu
Indonesian Journal of Cancer Vol 19, No 3 (2025): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i3.1319

Abstract

Colorectal cancer (CRC) is a major global health challenge, ranking as the third most prevalent cancer worldwide. Traditional tumor biopsies are invasive and limited by issues such as tumor heterogeneity and the inability to perform repeated sampling. Liquid biopsy, a non-invasive diagnostic approach that analyzes biomarkers in bodily fluids like blood, offers an innovative solution to these challenges. By detecting circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), exosomes, and tumor-educated platelets (TEPs), liquid biopsy allows for real-time tumor monitoring, early cancer detection, and personalized treatment strategies. This review explores the clinical applications of liquid biopsy in CRC, highlighting its potential for early detection, monitoring treatment response, and guiding customized therapies. Key biomarkers such as CEA, ctDNA, CTCs, and exosomal miRNAs offer insights into tumor dynamics and prognosis. While liquid biopsy shows promise for broad clinical use, challenges remain in standardizing methodologies and validating its efficacy through large-scale trials. Advances in technology and improved biomarker discovery are expected to enhance the accuracy and utility of liquid biopsy, making it a pivotal tool in CRC management and beyond.