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All Journal Majalah Obstetri dan Ginekologi Asian Journal of Health Research
Kharizmatika
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Diagnostic and Treatment Challenges of Recurrent Tuberculosis in Patient with Drug-Induced Hepatotoxicity: A Case Report Devanda, Kasilda Pasha; Avelline, Kendraadine Dheayu; Lauwis, Keziah Queency; Kharizmatika; Hayati, Khofifah Bela Rachmanu; Adiwinoto, Ronald Pratama; Nugraheni, Pramita Anindya; Rasyida, Annisa Ullya
Asian Journal of Health Research Vol. 3 No. 3 (2024): Volume 3 No 3 (December) 2024
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v3i3.195

Abstract

Introduction: Pulmonary tuberculosis (TB) remains one of the most significant global health challenges, especially complicated by cases with incomplete treatment histories. The recurrence of TB poses diagnostic and therapeutic dilemmas that significantly impact patient outcomes. Case Presentation: We report a case of a 57-year-old female patient presenting with recurrent pulmonary TB after an incomplete treatment course. The patient's history revealed gaps in adherence to the prescribed TB regimen, leading to multiple relapses. In this study, we found that patients undergoing TB treatment may experience liver damage as a result of the TB medication, also known as DIH. Comprehensive diagnostic procedures, including chest radiography, sputum culture, and molecular testing, confirmed recurrent TB. The patient's clinical manifestations, treatment plan, and response to therapy are detailed. Conclusion: Recurrent TB is common, particularly in older adults, and is influenced more by environmental factors than occupation. Additionally, ATT poses risks of hepatotoxicity, especially in malnourished patients, underscoring the importance of managing side effects and addressing factors like malnutrition to prevent complications and improve outcomes. This case underscores the importance of complete adherence to TB treatment regimens and highlights the challenges in managing recurrent TB. It emphasizes the need for robust follow-up, patient education strategies, early diagnosis, and prompt intervention to prevent recurrence and enhance patient outcomes.
The effect of date fruit consumption on delivery outcomes: A systematic review Kharizmatika; Soediono, Mochammad Ridhwan
Majalah Obstetri & Ginekologi Vol. 34 No. 1 (2026): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V34I12026.61-69

Abstract

HIGHLIGHTS Consuming date fruit in late pregnancy may enhance labor outcomes by reducing labor duration, speeding up cervical dilation, and decreasing the need for induction. Healthcare providers might recommend it as a natural dietary intervention, while further research should standardize protocols and determine optimal dosages.   ABSTRACT Objective: This systematic review examines the impact of date fruit consumption during pregnancy on labor and delivery outcomes. Materials and Methods: A systematic search was carried out utilizing PubMed, Cochrane Library, and ScienceDirect databases to identify systematic reviews and meta-analyses published within the last five years. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria were adhered to in order to identify studies and extract data. Quality evaluation was carried out utilizing the AMSTAR tool to ensure methodological rigor. Results: Among 3,528 initial records, 255 articles met eligibility criteria, with 4 systematic reviews included for analysis. Date fruit consumption was associated with shortened first stage of labor (pooled effect size: -50.09 to -76.16 minutes), reduced second stage duration (pooled effect size: -7.7 to -15.05 minutes), accelerated cervical dilatation (pooled effect size: 0.94 to 1.15 cm), and decreased gestation duration (pooled effect size: -0.30 weeks to -1.97 days). Improved Bishop score (MD/WMD: 2.45 to 2.47) and decreased labor induction frequency (RR: 0.48 to 0.6) were also observed. Heterogeneity in outcomes suggests variable effects across studies. Conclusion: Date fruit consumption in late pregnancy shows potential benefits for labor outcomes, including shorter duration of labor stages, accelerated cervical dilation, and reduced need for labor induction. Healthcare providers may consider recommending date fruit as a natural dietary intervention to enhance maternal and neonatal health during childbirth. Further research should standardize protocols, explore optimal dosages, and elucidate mechanisms to strengthen evidence-based recommendations.
Co-Authors ANNISA ULLYA RASYIDA Avelline, Kendraadine Dheayu Devanda, Kasilda Pasha Hayati, Khofifah Bela Rachmanu Lauwis, Keziah Queency Nugraheni, Pramita Anindya Ronald Pratama Adiwinoto Soediono, Mochammad Ridhwan