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Pancreas Protective Effects of Telang Flower Extract (Clitoria ternatea L.) Against induced Male White Rats (Rattus norvegicus) Aloksan Edi Kamal, Sainal; Rusli, Rusli; Fani Temarwut, Farid; Biana Sary, Skolastika
Jurnal Farmasi Sandi Karsa Vol 8 No 2 (2022): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v8i2.115

Abstract

Studies have been conducted on the protective effects of pancreatic telang flower extract (Clitoria ternatea L.) against white rats (Rattus norvegicus) induced by alloxane-induced by laboratory experiential methods. Thegoal is to determine the protective effect of pancreatic telang flower extract (Clitoria ternatea L.) against white rats (Rattus norvegicus) induced by alloxane which has the potential to be anti-diabetic. The mice used were 15 heads, the mice were divided into 5 groups. Each group consisted of 3 mice. Three groups were given a suspension of Telang Flower Extract at a dose of 150 mg/kgBB, 300 mg/kgBB, 450 mg/kgBB, and 1 group as a negative control was given a 1% Na-CMC suspension w/v. The administration of telang flower extract was carried out for 5 days and induced by aloksan of 150 mg / KgBB for 2 days. Blood draws are carried out 3 times, namely on the first day, day 6, and day 8 and then measurements of glucose and albumin levels are carried out. Based on the research that has been carried out, it can be concluded that the administration of telang flower extract (Clitoria ternatea L.) at a dose of 150 mg/KgBB,300 mg/KgBB, and 450 mg / KgBB have a protective effect not significantly different.
Aktivitas Antioksidan Granul Instan Ekstrak Bunga Telang (Clitoria ternatea L) Sebagai Antidiabetes: Antioxidant Activity Of Instant Granules Of Telang Flower Extract (Clitoria ternatea L) As Antidiabetes Fani Temarwut, Farid; Arif, Mutmaina; Rahmatia
Media Farmasi Vol 21 No 1 (2025): Media Farmasi Edisi April 2025
Publisher : Jurusan Farmasi Poltekkes kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v21i1.1265

Abstract

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action, or both. DM can be classified into several types, namely, type 1 DM, type 2 DM, existing type DM. Type 2 DM is one of the most common types, which is more than 90-95%. The purpose of this study was to formulate instant granules of Telang Flower extract (Clitoria ternatea L) and determine antioxidant activity and antidiabetic activity. This research is a laboratory experiment involving instant granule formulations that are tested for physical characteristics, then tested for antioxidant activity using DPPH and Pretest-Postest Control Group Design antidiabetic activity test on White Rats. The results of observations of instant granule characteristics testing which include organoleptical tests, flow speed, angle of repose, moisture content, dissolving time and pH meet the granule requirements. the results of the antioxidant activity test IC50 value F1 155.39, F2 115.73, F4 143.93 and F5 148.25 where the four formulas show moderate antioxidant characteristics, while the IC50 nlai F5 262.86 is included in the weak antioxidant category. The measurement of blood glucose levels before alloxan induction (pree) and after alloxan induction (mid) increased where in FI 9. 63>267.33 mg/dL, F2 105.66>248.00, mg/dL F3 99.00>217.66 mg/dL F4 99.00>263.33 mg/dL and F5 104.00>247.33 mg/dL, while in healthy control (without treatment) no increase occurred 97.66 mg/dL, while the decrease in glucose levels after alloxan induction (mid) and after being given instant granule preparations (post) on the 11th day decreased where for F1 267.33 <132.67 mg/dL, F2 248.00 <147.00, mg/dL F3 217.66 <119.33 mg/dL F4 263.33 <132.67 mg/dL and F5 247.33 <114.00 mg/dL. So it can be concluded that the instant granule preparation formulation of Telang Flower extract (Clitoria ternatea L) with a dose of 450 mg/KgBB with a concentration of PVP 3.5% as a binder meets the requirements of instant granule characteristics, also has moderate antioxidant activity and has the lowest blood glucose lowering effect compared to other formulas.
Sosialisasi dan Pelatihan Aplikasi Google Form Sebagai Kuesioner Online untuk Pendataan Peserta Kartu Indonesia Sehat (KIS) Desa Aeng Towa Kabupaten Takalar Aziz, Firman; Firmansyah; Ishak, Pertiwi; Fani Temarwut, Farid; Fadhila Amri, Nur; Abasa, Sustrin
GLOBAL ABDIMAS: Jurnal Pengabdian Masyarakat Vol. 1 No. 2 (2021): Nopember 2021, GLOBAL ABDIMAS
Publisher : Unit Publikasi Ilmiah Perkumpulan Intelektual Madani Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51577/globalabdimas.v1i2.357

Abstract

Tujuan kegiatan Sosialisasi dan Pelatihan Aplikasi Google Form sebagai Kuesioner Online untuk Pendataan Peserta Kartu Indonesia Sehat (KIS) Desa Aeng Towa Kabupaten Takalar adalah untuk memberikan pengetahuan kepada mitra dalam mempersipakan diri untuk pencatatan digital. Peserta dalam program ini adalah mitra yang akan melaksanakan pendataan Peserta Kartu Indonesia Sehat (KIS) Desa Aeng Towa Kabupaten Takalar. Permasalahan peserta terletak pada pengetahuan kuesioner online dalam hal ini adalah tidak dapat memanfaatkan Google Form untuk membuat kuesioner online yang dapat memudahkan dalam pencatatan Peserta Kartu Indonesia Sehat (KIS) Desa Aeng Towa Kabupaten Takalar. Hasil kegiatan pengabdian adalah peserta mengetahui dan memahami tentang cara membuka Google Form, mendesain formulir, dan jenis jenis pertanyaan yang bisa diajukan serta menggunakan kuesioner tersebut untuk pendataan peserta Kartu Indonesia Sehat (KIS) Desa Aeng Towa kabupaten Takalar.