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All Journal Jurnal Sains dan Teknologi International Journal of Health and Pharmaceutical (IJHP)
Chiuman , Linda
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Computer Science & IT Education Nursing Public Health

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Potential Test of Jojoba Oil-Based Sunscreen in Lotion Preparations Anggriani H, Theresia; Novalinda Ginting, Chrismis; Chiuman , Linda; Rosari, Anita
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 2 (2024): May 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i2.249

Abstract

This study aimed to determine the formula of anti-aging cream using lemongrass leaf extract. The treatment by giving respondents lemongrass leaf extract and using moisture, evenness, pore, spot, and wrinkle as parameters. Human skin provides protection on the surface of the body against the influence of the surrounding environment. Skin can experience aging, especially in areas that are often exposed to direct sunlight such as the face, neck, upper arms, and hands. Aging is a process experienced by humans in their 30s whose functions in the human body are decreasing, for example, thinning skin, wrinkles, rough skin, and dark spots on the face. Treatment to prevent aging of the skin by using an antioxidant product such as flavonoids because it has the function of preventing or neutralizing free radicals. In Indonesia, several species of plants can be found that function as food and cosmetic ingredients. The lemongrass leaf extract which contains antiaging are Alkaloids, Flavonoids, and Tannins. The data were analysed by using the Kolmogorov-Smirnov method to determine homogeneity and normality. Then, if the data is normal, it is continued to be analysed using the One-Way ANOVA method to determine the average difference between groups. There is a difference between treatments, and it is continued with the Post-hoc Tukey HSD test. The higher the concentration of extract used, the greater the anti-aging productivity formed. It is concluded, the best anti-aging effect is a concentration of 9% with increase in moisture, evenness, pore reduction, reducing spots and wrinkles.
Antibacterial and Anti-Diarrheal Potential of Andaliman (Zanthoxylum acanthopodium DC) Methanol and Nanoemulsion Extract Chiuman , Linda; Singh, Wanti Natalia; Saragih, Delfia Rehuela; Rahyani, Oktavini Handayani Fikri; Rena Meutia
JST (Jurnal Sains dan Teknologi) Vol. 13 No. 2 (2024): July
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/jstundiksha.v13i2.80295

Abstract

Diarrhoea is one of the prevalent global health problems, causing cases of death and morbidity in various age groups for people around the world. Andaliman is a typical herbal plant of North Sumatra with multiple benefits that have been studied previously. This study aims to analyze the antibacterial and anti-diarrheal potential of methanol extract and nanoemulsion of Andaliman (Zanthoxylum acanthopodium). This study used laboratory experimental research with a post-test-only group design. Antibacterial testing was carried out using the disc diffusion method with three repetitions of four extract concentrations. The standard group used ciprofloxacin 5μg, and the control group used DMSO. Then, we continued with the microdilution method with an initial concentration of 500mg/Dl extract to determine the minimum inhibitory and kill levels. An anti-diarrhoea study was conducted using 30 Wistar rats treated with nanoemulsion extract. The standard group was given loperamide 3 mg/KgBB, and the control group was given CMC Na 0.25 ml. Rats were induced with castor oil, and the frequency of defecation and liquid faeces were observed for 1 hour. Andaliman (Zanthoxylum acanthopodium) methanol extract showed a moderate inhibitory effect against E.Coli, with KHM and KBM of 55.56 mg/mL. Potential as anti-diarrhoea, Andaliman nano emulsion extract showed a significant difference at 50mg/KgBB dose for diarrhoea frequency and loose stools. However, no significant differences were found in gastrointestinal and entero-pooling results. Based on the results, it can be concluded that methanol extract and nanoemulsion of andaliman (Zanthoxylum acanthopodium) showed antibacterial activity against E.Coli and showed anti-diarrhea potential. The expected implication is that andaliman can be an alternative treatment for diarrhoea, especially for diarrhoea caused by Escherichia coli.
Co-Authors Anggriani H, Theresia Ginting, Chrismis Novalinda Rahyani, Oktavini Handayani Fikri Rena Meutia Rosari, Anita Saragih, Delfia Rehuela Singh, Wanti Natalia