Gusa, Putri Heryalien
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Evaluation of the Quantity and Quality of Antibiotic Use in Inpatient Pediatric Urinary Tract Infection (UTI) Patients at RSUD KRMT Wongsonegoro Semarang Gusa, Putri Heryalien; Annisaa', Eva; Dini, Intan Rahmania Eka
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 3 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i3.41447

Abstract

Background: Antibiotics are the main drug in the treatment of various infectious diseases. The high use of antibiotics can cause bacterial resistance to antibiotics so it is necessary to evaluate antibiotics both in quantity (amount of antibiotics used) and quality (accuracy of antibiotic use).Objective: This study was conducted to determine the quantity and quality of antibiotic use in pediatric urinary tract infection (UTI) patients hospitalized at KRMT Wongsonegoro Hospital Semarang.Methods: This study was a retrospective cross-sectional study. The study materials were medical records of pediatric UTI patients who were hospitalized at KRMT Wongsonegoro Hospital Semarang. Analysis was performed qualitatively using the Gyssens method and quantitatively using the ATC/DDD and DU90% methods.Results: There were 46 prescriptions from 43 pediatric UTI patients. The most commonly used single antibiotic was ceftriaxone (47.73%). Evaluation of the quantity of antibiotic use obtained the total DDD (Defined Daily Dose) value of pediatric UTI patients in the 2019-2022 period was 40.39 DDD/100 patient-days. Antibiotics that fall into the DU90% segment are ceftriaxone and cefotaxime. Evaluation of the quality of antibiotic use obtained 8 of antibiotic use is appropriate/wise.Conclusion: There is still inappropriate antibiotic use in pediatric UTI patients at KRMT Wongsonegoro Hospital in 2019-2022.