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Hubungan Efikasi Diri dengan Stres Kerja pada Petani Tembakau di Kecamatan Kalisat-Jember Andriyani, Alfia; Wuryaningsih, Emi; K, Enggal Hadi
Pustaka Kesehatan Vol 11 No 3 (2023): Volume 11 No.3, 2023
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v11i3.11597

Abstract

The increase in self-efficacy in tobacco farmers has an important role related to occupational stress management. This research aimed to analyze the correlation between self-efficacy with the occupational stress of tobacco farmers in the subdistrict Kalisat Regency Jember. The method of this research was a cross-sectional study with 100 tobacco farmers using a cluster sampling technique. The study was conducted in April in Kalisat District, Jember Regency. Bivariate analysis used Pearson correlation (α <0.1; CI = 90%). The research instrument of self-efficacy used GSE (General Self-Efficacy) with α Cronbach =0.76-0.9 and DASS (Depression Anxiety Stress Scale) with α cronbach=0.88. This research has passed the research feasibility through the Health Research Ethics Commission (KEPK) of the Faculty of Dentistry, University of Jember No. 270/UN 25.8./KEPL/DL. The results showed high self-efficacy (30,31%) and low occupational stress (17,39%). The results of the univariate analysis showed high self-efficacy with an average value of 30,31% (sd= 5,75) and low occupational stress with an average value of 17,39 (sd=5,79). The results of the bivariate analysis showed that there was a significant relationship between self-efficacy and occupational stress with Pearson correlation values ​​p <0,000 (α <0.1; CI = 90%). Behavior showed by the tobacco farmers is that they highly believe themselves to work in tobacco farms. One who has high self-efficacy is able to overcome occupational stress. The results of this study are expected to help to improve occupational health services. This functioned to maintain and improve the health status of tobacco farmers.
Effect of Moringa Oleifera Leaf Nanoparticles on IL-10 in Vivo Model of Oral Cavity Malignancy Asmaningdiah, Mariana; Andriyani, Alfia
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11489

Abstract

Interleukin-10 (IL-10) which is secreted by Th 2 cells. Interleukin- 10 is an anti-inflammatory cytokine that plays an important role in the regulation of the host immune response by inhibiting the release of pro-inflammatory mediators. Moringa leaf nanoparticles (Moringa oleifera) are products that contain various bioactive mediators that can play a role in inflammation. The aim of this study was to determine the effect of administering Moringa leaf extract nanoparticles on IL-10 levels in oral cavity cells undergoing malignant transformation. Eighteen male Wistar rats (R. novergicus) were used as animal models that underwent benzo(a)pyrene induced malignant transformation in the oral cavity. Moringa leaf extract nanoparticles with concentrations of 0.250 mg/mL, and 0.500 mg/ were given to the treatment group for 14 days. The results of IL-10 levels were evaluated using the ELISA method. Data analysis using the Kruskall-Wallis test was carried out to analyze differences between groups. Aplication Moringa oleifera leaf nanoparticles with concentrations of 0.250 mg/mL, and 0.500 mg/mL were able to reduce levels of IL-10 in oral cells undergoing malignant transformation. The results of this study showed that the p-value = 0.726 (> 0.05) which means that there was no effect of the application of moringa leaf extract nanoparticles in a mouse model with malignant transformation of oral cells on reducing IL-10 levels.