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Formulation and Evaluation of Anti-Acne Activity of Gel Pineapple Peel (Ananas comosus L.) Extract on the Growth of Propionibacterium acnes Latu, Saparuddin; Firman, Imran; Yaqkin-P, Andi Muh.; Musliani, Musliani
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.286

Abstract

Pineapple peel contains many compounds, namely flavonoids, tannins, saponins, phenolics, steroids, alkaloids and bromelin enzymes. Acne is a chronic inflammatory disease of the pilosebaceous glands. One of the bacteria that causes acne is Propionibacterium acne. Preparations that can be made for anti-acne are gel preparations. This study aims to determine whether the ethanol extract of pineapple peel (Ananas comosus L.) can be made into an anti-acne gel preparation and to find out at what concentration the ethanol extract of pineapple peel (Ananas comosus L.) in an anti-acne gel preparation can provide inhibitory activity on the development of Propionibacterium acne bacteria. This research method is true experimental by making anti-acne gel preparations of pineapple peel extract (Ananas Comosus L.) with various concentrations of 2%, 3%, 5% and testing the activity of the preparation against Propionibacterium acne using the agar well method. The results of the gel preparation formula showed that there were significant differences before and after the cycling test in both organoleptic, homogeneity, pH, viscosity, spreadability and adhesion tests. The activity test results obtained were that the largest inhibition zone was the 5% concentration, namely 12.7 mm, which was in the strong category, while the 3% concentration, which was 11.03 mm, and the 2% concentration, which was 8.8 mm, was included in the moderate category.
Formulasi Dan Uji Stabilitas Sediaan Serum Dari Ekstrak Etanol Kulit Buah Pisang Muli (Musa Acuminate Linn) Sebagai Antioksidan Safaruddin; Irmayani; Kalsum, Ummu; Firman, Imran; Amin, Rahmasinar
INHEALTH : INDONESIAN HEALTH JOURNAL Vol. 3 No. 2 (2024): INHEALTH JOURNAL
Publisher : CV. Eureka Murakabi Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56314/inhealth.v3i2.246

Abstract

Salah satu tanaman yang dapat dijadikan sebagai obat adalah tanaman Kulit Buah Pisang Muli (Musa Acuminata Linn). Daun dan kulit batang buah pisang muli dimanfaatkan sebagai obat berbagai macam penyakit, seperti pendarahan usus, amandel, memperbaiki pertumbuhan rambut. Kulit Buah Pisang Muli (Musa Acuminata Linn dapat dijadikan sediaan serum Kulit Buah Pisang Muli (Musa Acuminata Linn sebagai antioksidan, metode penelitian dilakukan secara eksperimental laboratorium, ekstrak Kulit Buah Pisang Muli (Musa Acuminata Linn) dimaserasi menggunakan pelarut etanol 96%. Dibuat sediaan serum dengan tiga konsentrasi 3%, 5%, 7%, kontrol negatif K(-), dan kontrol positif K(+) kemudian dilakukan uji organoleptis, homogenitas, pH, daya sebar, viskositas dan cycling test yang dilakukan selama 6 siklus. Hasil uji Serum Dari Ekstrak Etanol Kulit Buah Pisang Muli (Musa acuminata Linn) dapat dijadikan sediaan serum yang stabil secara fisika dan kimia serta sediaan Serum Dari Ekstrak Etanol Kulit Buah Pisang Muli (Musa Acuminata Linn) memiliki khasiat sebagai antioksidan. Hasil penelitian menunjukkan pada formula I memiliki aktivitas nilai IC50 50,25 µg/mL, formula II memiliki aktivitas nilai IC50 30,96 µg/mL, formula III memiliki aktivitas nilai 7,85 µg/mL, sedangkan control positif memiliki aktivitas nilai IC50 13,35 µg/mL. aktivitas antioksidan dari semua sediaan memiliki sifat antioksidan yang sangat kuat karena <50 ppm kecuali formula II yang memiliki sifat antioksidan kuat karena >50 ppm.
EVALUATION OF DRUG MANAGEMENT AT THE CAMBA COMMUNITY HEALTH CENTER UPTD, MAROS DISTRICT, 202 Firman, Imran; Alqadri, Dinar; Arifuddin, Adriana; Azis, Rahmawati
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 4 (2025): Vol. 2 No. 4 Edisi Oktober 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i4.1433

Abstract

Drug management is a series of pharmaceutical service activities involving aspects of planning, requesting, receiving, storing, distributing, controlling, recording, and reporting drugs. Drug management in CHCs is an important aspect because inefficiency will have a negative impact on health services. The purpose of this study was to evaluate drug management at the Camba Community Health Center UPTD so that it can be used as a reference material to improve the quality of drug management. This type of research is a non-experimental descriptive-observational study. The data used are data in the form of reports and documents on drug management at the community health center. The research instrument used an observation sheet with the references used being the Indonesian Minister of Health Regulation No. 74 of 2016 and the Indonesian Ministry of Health 2019 Technical Guidelines for Pharmaceutical Service Standards in CHCs. The results of the study indicate that drug management at the Camba Community Health Center UPTD is based on the Indonesian Minister of Health Regulation No. 74 of 2016 and the Indonesian Ministry of Health 2019 Technical Guidelines for Pharmaceutical Service Standards at CHCs in the planning aspect are included in the good category with a percentage value of 100%, the request aspect is 100% in the good category, the receipt aspect is 100% in the good category, the storage aspect is 87.5% in the good category, the distribution aspect is 66.7% in the sufficient category, the destruction and withdrawal aspect is 100% in the good category, the control aspect is 100% in the good category, the recording and reporting aspect is 100% in the good category. So it can be concluded that drug management at the Camba Community Health Center UPTD in 2024 has met the standards set by the Indonesian Ministry of Health.
Kajian Literatur mengenai Peran Apoteker dalam Interprofessional Collaboration di Pelayanan Kesehatan Firman, Imran
Sciences and Clinical Pharmacy Research Journal Vol. 2 No. 4 (2026): January
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/scpr.v2i4.5321

Abstract

Tujuan utama penelitian ini adalah untuk mengeksplorasi peran apoteker dalam kolaborasi interprofesional (interprofessional collaboration/IPC) di pelayanan kesehatan dan memahami dampaknya terhadap hasil klinis, kepatuhan pasien, serta efektivitas tim lintas profesi. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi pustaka, memanfaatkan literatur akademik terbaru yang relevan, termasuk artikel ilmiah dan laporan resmi. Data dikumpulkan melalui penelusuran literatur sistematis dan dianalisis secara deskriptif-induktif dengan tahapan identifikasi tema, reduksi data, kategorisasi konsep, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa apoteker memainkan peran penting dalam lima dimensi kolaborasi: kemitraan, koordinasi, kerja sama, pengambilan keputusan, dan hasil terapeutik. Bentuk kolaborasi yang ditemukan mencakup review obat, manajemen terapi, edukasi pasien, partisipasi dalam ward round, serta integrasi di praktik primer. Faktor pendukung meliputi kejelasan peran, komunikasi efektif, dukungan sistemik, co-location, dan teknologi komunikasi, sedangkan hambatan meliputi keterbatasan waktu, ketidakjelasan deskripsi tugas, serta tantangan dalam membangun identitas kolaboratif. Implikasi penelitian ini menekankan pentingnya strategi pendidikan interprofesional, penguatan identitas profesional, dan adaptasi budaya organisasi untuk meningkatkan efektivitas IPC. Kesimpulannya, optimalisasi peran apoteker dalam kolaborasi interprofesional tidak hanya meningkatkan hasil klinis dan kepatuhan pasien, tetapi juga memberikan kontribusi signifikan terhadap pengembangan teori dan praktik kolaborasi lintas profesi di pelayanan kesehatan.