Namira, Safa Marety
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BMP-7 Expression After Induction of Hydroxyapatite Bovine Tooth Graft Gel as A Socket Preservation of The Alveolar Bone (Laboratory Experimental of The Alveolar Bone) Zubaidah, Nanik; Namira, Safa Marety; Aryandhita, Amanda Paramitha Putri; Firyasasty, Beffano Roziq Herdymunas; Cahyani, Febriastuti
Conservative Dentistry Journal Vol. 13 No. 2 (2023): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v13i2.2023.60-63

Abstract

Background: Hemisection is an endodontic surgical procedure that can leave alveolar bone defects. Changes in the dimensions of the alveolar bone can be minimized by preserving the alveolar bone socket using a bone graft. Induction of Hydroxyapatite Bovine Tooth Graft (HAp-BTG) in the alveolar bone socket is expected to increase the expression of BMP-7 which is a growth factor in osteogenesis. Purpose: To describe the increase in BMP-7 expression after induction of hydroxyapatite bovine tooth graft gel as a socket preservation of the alveolar bone of Wistar rats on the 14th and 28th days. Methods: 28 Wistar rats were extracted on the lower left incisor. Post-extraction sockets were induced by Polyethylene Glycol (PEG) as the control group and HAp-BTG + PEG as the treatment group. On the 14th and 28th day the Wistar rats were euthanized and the mandibles were taken. By using immunohistochemical staining on anatomic histopathological examination, BMP-7 expression was observed using a microscope with 1000í— magnification. The research results were analyzed using One Way ANOVA. Results: There was a significant increase in BMP-7 expression between the control group and the treatment group. Conclusion: BMP-7 expression after induction of hydroxyapatite bovine tooth graft gel as a socket preservation of the alveolar bone of Wistar rats increased on the 14th and 28th days.
Apexification with mineral trioxide aggregate on post trauma right maxillary central incivus teeth Masa, Maria Margaretha S. Nogo; Pratiwi, Dian Dwi; Cahyani, Febriastuti; Zubaidah, Nanik; Namira, Safa Marety; Wulandini, Raden Ajeng; Tanzil, Muhammad Iqbal; Oktaria, Wanda; Saraswati, Widya
Conservative Dentistry Journal Vol. 13 No. 2 (2023): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v13i2.2023.81-84

Abstract

Background: Trauma often occurs in the maxillary anterior teeth in both children and adults. This usually causes the pulp of a tooth whose root is not yet fully formed to experience necrosis, and the apex closure stops causing the apex to be wide and open. Apexification is a method to induce a calcified barrier in necrotic roots with open apex. Treatment with Mineral trioxide aggregate (MTA) can shorten treatment time and has a higher long-term success rate than using Ca(OH)2. Purpose: The aim of this report is to describe apexification cases using MTA on a non-vital right maxillary central incisor. Case: A 21-year-old male patient came to the Dental Conservation Clinic at Airlangga University Dental Hospital with complaints of broken and discolored front teeth. The tooth was broken after falling ± 10 years ago (2013) while playing football, it was swollen and painful, but in the last ± 1 year (2022) it has never hurt again. The patient's medical history revealed no systemic abnormalities. Objective examination of tooth 11 class IV ellis fracture, negative percussion and bite test, surrounding normal gingiva, no mobility. The radiographic appearance of tooth 11 shows a wide open apex and a radiolucency at the root tip. Vitality of non-vital teeth, Diagnosis of pulpal necrosis with asymptomatic apical periodontitis. Case Management: In this case, the treatment plan is endodontic treatment in the form of apexification with MTA material. The obturation technique was performed using warm thermoplastic (backfill) and accompanied by a fixed restoration using a fiber post and all porcelain crown with a good prognosis for patient care. Conclusion: Apexification with MTA with post and IPS Emax crown restoration is a good treatment option for immature right maxillary central incisor with open apex. The patient is satisfied because the teeth can return both aesthetically and functionally according to the stomatognathic system.