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Gusnelti, Yesi
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Biochemistry, Genetics & Molecular Biology Public Health

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Pengaruh Pemberian Ekstrak Etanol Daun Sirsak(Annona muricata L.) Terhadap Kadar Kolesterol Total Pada Mencit (Mus musculus) humaira, vilma; Gusnelti, Yesi; Nurjanah, Elsa
Jurnal Medisains Kesehatan Vol. 3 No. 1 (2022): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v3i1.244

Abstract

Hiperkolesterolemia merupakan salah satu faktor risiko utama dalam perkembangan penyakit kardiovaskular. Pengobatan menggunakan tanaman berkhasiat obat sudah lebih dulu diterapkan dari obat-obat modern. Daun sirsak (Annona muricat L. ) telah digunakan untuk pengobatan bermacam penyakit salah satunya sebagai penurun kadar kolesterol total. Tujuan penelitian ini untuk menguji apakah ekstrak daun sirsak dapat menurunkan kadar total kolesterol mencit yang di induksi makanan lemak tinggi (MLT). Penelitian ini menggunakan hewan uji mencit jantan sebanyak 24 ekor yang dibagi 4 kelompok yaitu kelompok kontrol yang tidak diberi perlakuan, dan kelompok yang diberi perlakuan ekstrak daun sirsak dengan dosis 2mg/BB, 6mg/BB, dan 8mg/BB diberikan secara oral selama 7 hari. Hasil penelitian menunjukkan bahwa pemberian ekstrak etanol daun sirsak dapat menurunkan kadar kolesterol total pada mencit dengan signifikan (p<0,05). Data di peroleh secara statistik dengan uji one way anova
Perbandingan Aktivitas Anti Bakteri Ekstrak Daun Pepaya (Carica Papaya L) Dan Daun Kelor (Moringa Oleifera L) Terhadap Bakteri Staphylococcus Aureus Abeiasa, M Saka; Gusnelti, Yesi; Warma Putri, Romi Yanti
Jurnal Medisains Kesehatan Vol. 3 No. 2 (2022): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v3i2.252

Abstract

This study aims to determine the comparison of papaya leaf extract (Caricapaya L) and Moringa leaf (Moringa oleifera L) against staphylococcus aureus bacteria. The type of research used is a laboratory experiment with a completely randomized design (CRD), using the nutrium agar method, namely using disk paper that already contains papaya leaf extract (Carica papaya L.) and Moringa leaf (Moringa oleifera L.) against staphylococcus aureus bacteria. the results of the inhibition zone of papaya leaf bacteria at a concentration of 25-100% experienced ups and downs, at a concentration of 25% with an average inhibition of 5.6mm and at a concentration of 50% increased with an average inhibition of 6mm then at a concentration of 75% decreased with an average of 5.8mm and at a concentration of 100% increased by an average of 6.6mm. Moringa leaves have the inhibitory activity of staphylococcus aureus bacteria from a concentration of 25% to 100% also experience an up and down phase, at a concentration of 25% with an average of 5.6 mm and at a concentration of 50% it increases with an average of 6.2 and at the concentration of 75% also increased with an average of 7 and the concentration of 100% decreased with an average of 6.5 so that Moringa leaves have an antibacterial inhibitory power. There is a difference between papaya leaf extract and Moringa leaf extract, namely at concentrations of 25%, 50% 75% and 100%
Evaluasi Penggunaan Obat Glimepirid Pada Pasen Diabetes Melitus Tipe 2 Di RS Tamar Medical Centre Pariaman Humaira, Vilma; Gusnelti, Yesi; Abeiasa, M. Saka; Fadya Syafitri, Aqilla
Jurnal Medisains Kesehatan Vol. 5 No. 1 (2024): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v5i1.340

Abstract

Evaluation of the use of diabetes mellitus type 2 drugs at Tamar Medical Center Pariaman Hospital aims to determine usage patterns and evaluate the rationality (appropriateness) of using antidiabetic drugs. The research method used is descriptive with direct data sampling. A total of 30 samples were evaluated, the conclusion of this research is that from the first ten points regarding the correct dose, from 30 respondents, 80.64% (25 people) had used the correct dose of medication and 19.36% (5 people) had not used the correct dose at Tamar Hospital. medical pariaman and from the second ten points about the right way to use it, from 30 respondents 59.31% (18 people) had the right way to use the drug glimepiride, 40.69% (12 people) did not use the medicine correctly and from the third ten points about the right time 85.62% (27 people) were on time when using glimepirid, 14.38% (3 people) were not using glimepiride on time)
Co-Authors Abeiasa, Muhammad Saka Fadya Syafitri, Aqilla Nurjanah, Elsa Vilma Humaira Warma Putri, Romi Yanti