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All Journal Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Scientific Journal of Dermatology and Venereology Jurnal Teknokes
Andi Ipaljri
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Electrical & Electronics Engineering Engineering Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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The Role of Innate and Adaptive Immunity in Staphylococcal Scalded Skin Syndrome: A Systematic Literature Review Isramilda; Andi Ipaljri
Scientific Journal of Dermatology and Venereology Vol. 2 No. 1 (2024): Scientific Journal of Dermatology and Venereology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjdv.v1i2.50

Abstract

Introduction: The innate immune system provides immediate protection in the event of an infection, while the adapted immune system provides a more specific response and has the ability to remember specific pathogens, thereby protecting the body from similar infections in the future. This study aimed to present the role of innate and adaptive immunity in staphylococcal scalded skin syndrome (SSSS). Methods: The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the role of innate and adaptive immunity in staphylococcal scalded skin syndrome. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Results: Five studies were included in this study. A combination of innate and adapted immune systems work together to overcome SSSS infections. Conclusion: The innate immune system provides a rapid initial defense, while the ad apted immune system provides a more specific response and the ability to form immune memory.
ANALISIS FAKTOR RIWAYAT KELUARGA DAN IMT DENGAN KEJADIAN STRIAE DISTANSAE PADA SISWI Rusdani; Andi Ipaljri; Brahyuna Lazdyana
Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Vol 14 No 3 (2024): Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam
Publisher : Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/zked.v14i3.1545

Abstract

Latar Belakang: Striae distensae atau yang dikenal dengan strectch mark adalah bekas luka liner yang terlihat berkembang di area kerusakan kulit akibat perengang kulit yang berlebihan. Banyak faktor risiko berbeda yang diklaim menjadi penyebab perkembangan striae distensae. Penyebab paling umum termasuk grow spurt selama masa pubertas pada remaja, kehamilan, genetik, index massa tubuh, penggunaan kortikosteroid, cushing syndrome, marfan syndrome, serta penurunan dan kenaikan berat badan yang cepat. Metode: Desain penelitian ini merupakan penelitian observasional yang bersifat analatik, dengan pendekatan cross sectional. Teknik pengambilan sampel yaitu probability random sampling pada populasi sebanyak 757 siswi sehingga didapati jumlah sampel minimun sebanyak 262 siswi. Analisis data yang digunakan analisis univariat dan analisis bivariat dengan uji Chi-Square. Hasil: Hasil analisis Chi-Square didapatkan hubungan riwayat keluarga dengan kejadian striae distensae pada responden dengan nilai p = 0,0001 (p<0,05), dan tidak didapatkan hubungan antara IMT dengan kejadian striae distensae pada responden dengan nilai p = 0,081 (p>0,05). Kesimpulan: Berdasarkan hasil penelitian ini diperoleh bahwa terdapat hubungan riwayat keluarga dengan kejadian striae distensae pada siswi. Dan tidak terdapat hubungan antara IMT dengan kejadian striae distensae pada siswi. Kata Kunci : Striae distensae, Riwayat Keluarga, IMT
Comparative in Vitro Antibacterial Activity of Red Ginger (Zingiber Officinale Var. Rubrum) Extract and Conventional Antibiotics Against Pathogenic Escherichia Coli Isramilda, Isramilda; Andi Ipaljri; Kinanthi Amalia Putri
Jurnal Teknokes Vol. 18 No. 3 (2025): September
Publisher : Jurusan Teknik Elektromedik, Politeknik Kesehatan Kemenkes Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The increasing incidence of antibiotic resistance in Escherichia coli poses a significant challenge to public health, as the effectiveness of conventional antibiotics such as ciprofloxacin continues to decline due to the emergence of resistant E. coli strains. This study aims to evaluate red ginger extract's in vitro antibacterial activity against Escherichia coli and determine the optimal concentration for bacterial inhibition.  This research aims to determine the effectiveness of red ginger extract with concentrations of 60%, 80%  and 100% on the growth of Escherichia coli. Research method using a laboratory-based experimental study was conducted using red ginger extract prepared via ethanol maceration at concentrations of 60%, 80%, and 100%. The extract's antibacterial activity against E. coli was evaluated using the disc diffusion method following CLSI guidelines, with ciprofloxacin (500 mg) as a positive control and 95% ethanol as a negative control. Each treatment was replicated five times. Inhibition zones were measured after 24 hours of incubation at 37°C. The results of the study show that red ginger extract demonstrated significant antibacterial activity against E. coli, with mean inhibition zones of 6.08 ± 0.98 mm, 6.48 ± 1.21 mm, and 5.20 ± 1.89 mm for 60%, 80%, and 100% concentrations, respectively. The 80% concentration showed optimal inhibition activity, while the higher concentration (100%) demonstrated reduced effectiveness. Statistical analysis confirmed significant treatment differences (p < .001, η² = 0.967). The positive control produced significantly larger inhibition zones (23.16 ± 1.67 mm, p < .05). This study concludes that red ginger extract exhibits moderate antibacterial activity against E. coli in vitro, with 80% concentration showing optimal efficacy. These findings suggest potential applications in developing natural antimicrobial agents, although further research is needed to elucidate mechanisms of action and evaluate clinical applications.
Co-Authors Brahyuna Lazdyana Isramilda, Isramilda Kinanthi Amalia Putri Rusdani