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Diczen, Diczen
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Terapi Latihan Fisik Pada Pasien Cedera Meniskus Tanpa Tindakan Operatif: Laporan Kasus Berbasis Bukti Diczen, Diczen; Sudarsono, Nani Cahyani
Majalah Kedokteran Indonesia Vol 74 No 6 (2024): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.74.6-2024-1632

Abstract

Introduction: Surgery for meniscus injuries has the potential to trigger osteoarthritis and early cartilage degeneration. This evidence-based case report aims to evaluate the effectiveness of physical exercise therapy compared to surgery in restoring knee function in a woman with a lateral discoid meniscus tear.Methods: A systematic literature search was conducted using databases such as PubMed, ScienceDirect, ProQuest, and Scopus. The focus of the search was on studies comparing the outcomes of physical exercise therapy and surgery for meniscus injuries.Result: Out of 737 identified articles, three relevant studies met the criteria and addressed the research question of this case report. These studies concluded that there was no significant difference between physical exercise therapy and surgery in restoring knee function in patients with meniscus injuries.Conclusion: Physical exercise therapy has proven effective as a safe alternative with the potential to reduce the risk of operative complications in patients with meniscus injuries. This non-invasive approach offers a viable option for maintaining knee function without increasing the risk of osteoarthritis or early cartilage degeneration.
Manfaat Adiponektin Dan Leptin Dalam Memantau Efek Latihan Fisik Terhadap Fungsi Adiposa Penderita Sindrom Metabolik Sudarsono, Nani Cahyani; Paramita, Bunga Listia; Diczen, Diczen; Nugroho, Dimas; Shabrina, Meisya
Majalah Kedokteran Indonesia Vol 73 No 4 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.4-2023-977

Abstract

Introduction: The Prevalence of metabolic syndrome (MetS) in Indonesia is increasing, with the highest age in the 45 – 54 years old, and high mortality and morbidity rates complications and cost. Biomarkers such as adiponectin, leptin, and their ratios may be useful in monitoring and quantifying patient's body fat tissue function improvement after exercise training. This study aims to determine adiponectin, leptin, and their ratios benefits in monitoring physical exercise effects on adipose tissue function in pre-elderly (45-59 years old) and elderly (greater than 60 years old) patients with MetS.Methods: Literature review through hand searching and pubmed database related to the benefits of leptin and adiponectin test in monitoring physical exercise effect on adipose function in the pre-elderly and/or elderly population with MetS.Results: Physical exercise significantly increased adiponectin levels (mean difference (MD): 0.42 µg/mL; 95% CI 0.23, 0.60, p less than 0.0001), and reduced leptin levels (MD: -1.89 ng /ml; 95% CI, -2.64, -1.14, p less than 0.0001). High-intensity aerobic exercise can even reduce serum leptin levels by 6.29 ng/ml (p less than 0.001), and increase serum adiponectin levels by 0.74 μg/ml (p = 0.04). This significant change mainly occurs in men with a Body Mass Index (BMI) of 30 kg/m2 and 25.0-29. 9 kg/m2.Conclusion: Adiponectin/leptin ratio examination has potential future benefits in MetS management as an evaluation physiological biomarkers related to exercise interventions. There are only a few capable laboratories, and expensive cost, so that its current implementation is mostly devoted to research. Adopting a healthy lifestyle, balanced nutrition, physical activity habits and regular physical exercise are still the best suggestions for preventing MetS.
Co-Authors Dimas Nugroho Nani Cahyani Sudarsono Nani Cahyani Sudarsono Paramita, Bunga Listia Shabrina, Meisya