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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
Abet Nego, Mario
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Potensi Interaksi Obat Tersering pada Pasien Sakit Kritis Abet Nego, Mario; Gayatri, Anggi
Majalah Kedokteran Indonesia Vol 73 No 4 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.4-2023-1036

Abstract

Abstract Patients in critical condition are potentially prone to experiencing drug interactions due to receiving polypharmacy accompanied by complex and dynamic clinical conditions. Drug interactions can decrease drug effectiveness, increase therapeutic responses, or even lead to toxic effects. Factors that can enhance the effects of drug interactions include advanced age, obesity, hypoalbuminemia, polymorphism, sepsis, kidney and liver insufficiency. Therefore, monitoring the potential for drug interactions becomes crucial as it can distinguish whether changes in a patient's condition are caused by drug interactions or the disease process itself. This literature review aims to discuss the potential for drug interactions and the monitoring of interaction effects in critically ill patients.
Co-Authors Gayatri, Anggi