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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
Riyanti, Euis Yuli
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Frekuensi Transfusi Darah Tidak Memiliki Hubungan Signifikan dengan Inkompatibilitas Transfusi Darah pada Pasien Thalassemia Akbar, Teuku Ilhami Surya; Riyanti, Euis Yuli; Khairunnisa, Khairunnisa; Wahyuni, Hendra
Majalah Kedokteran Indonesia Vol 73 No 4 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.4-2023-1069

Abstract

Introduction: Thalassemia is an inherited disease caused by genetic changes that decrease the rate of synthesis of one or more globin chains of hemoglobin (Hb) tetramer. Patients with thalassemia who have changes in Hb may require frequent blood transfusions as a result of these changes in Hb. As a result of an antigen reaction known as incompatibility, frequent blood transfusions might result in the production of antibodies. Incompatibilities with blood transfusions may result in immediate side effects or delayed reactions. The purpose of this study is to ascertain the association between the frequency of blood transfusions and the incompatibility of blood transfusions with regard to thalassemia patients at Cut Meutia General Hospital in North Aceh.Method: This research is a descriptive analytic with a cross-sectional approach, a retrospective study. The sample in this study was the medical records of thalassemia patients in the Pediatric Inpatient Room at North Aceh Cut Meutia General Hospital (RSUCM) for the 2021 period. The sampling technique was carried out by total sampling.Results: Obtained 66 samples, in the age category the majority of thalsemia patients aged 6-11 years with a percentage of 45.5% (30), and male sex with a percentage of 53% (35). The frequency of blood transfusions was obtained by the majority doing ≤12 times per year with a percentage of 86.4% (57) and the results of patient incompatibility were obtained by 27.3% (18) in all respondents who underwent blood transfusions.Conclusion: The results of this study concluded that there was no relationship between the frequency of blood transfusions (p=0.213) and the incompatibility of blood transfusions in thalassemia patients at RSUCM Hospital. Limitation of this study was small sample size.
Co-Authors Khairunnisa Khairunnisa Teuku Ilhami Surya Akbar Wahyuni, Hendra