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All Journal Oftalmologi: Jurnal Kesehatan Mata Indonesia Cermin Dunia Kedokteran
Said, George Raden Mas
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Education Health Professions Library & Information Science Medicine & Pharmacology Nursing

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Bilateral Herpes Simplex Keratoconjungtivitis: A Case Report Said, George Raden Mas; Mustaram, Arief Akhdestira
Oftalmologi : Jurnal Kesehatan Mata Indonesia Vol 4 No 3 (2022): Jurnal Oftalmologi
Publisher : Pusat Mata Nasional Rumah Sakit Mata Cicendo Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ojkmi.v4i3.41

Abstract

Introduction: Herpes Simplex Virus (HSV) is one of the DNA viruses known to infect the human eye. Herpes simplex keratitis is, in general, a unilateral disease. In patients with weakened immune systems, simultaneous bilateral involvement is an uncommon event.Purpose: To report a case of bilateral herpes simplex keratoconjunctivitisCase Report: A 22-year-old man arrives with the primary complaint of redness in both eyes in the last four days. The patient complained of blurred vision, tearing, and foreign body sensations. Ophthalmology examination of both eyes revealed a visual acuity of 1.0 in the right eye and 0.8 in the left eye, a dendritic lesion, and decreased corneal sensation. The patient was diagnosed with bilateral keratoconjunctivitis HSV and was treated with acyclovir ointment, levofloxacin eye drops, acyclovir 400 mg five times daily, and vitamin C 500 mg.Discussion: Bilateral herpes simplex keratitis can occur in both immunocompromised and immunocompetent individuals. Recurrence of HSV infectious keratitis is common. Factors such as emotional stress, fever, postoperative tear dysfunction, ultraviolet (UV-A) radiation exposure, and ocular (accidental or surgical) trauma have also been related to the reactivation of the herpes simplex virus. History, physical, and laboratory examinations support the patient’s diagnosis to get the appropriate treatment.Conclusion: Due in part to the virus's increased virulence or changed host vulnerability, concurrently occurring bilateral herpetic keratitis has a high incidence of consequences. Delaying the advancement of corneal damage and lessening the intensity and frequency of viral assaults necessitates the timely administration of medicine upon diagnosis.
Penatalaksanaan Selulitis Praseptal di Praktik Kedokteran Pedesaan: Tantangan dan Keberhasilan Terapi – Laporan Kasus: Laporan Kasus Ohman, Selvania; Said, George Raden Mas
Cermin Dunia Kedokteran Vol 53 No 08 (2026): Agustus 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i08.2088

Abstract

Introduction: Preseptal cellulitis is an infection localized to the anterior portion of the orbital septum. The most common causes are Staphylococcus aureus and Streptococcus species. Beta-lactam antibiotics are considered the first-line treatment. However, rural settings pose challenges due to limited diagnostic resources and widespread antibiotic use without medical supervision. Case: A 29-year-old woman presenting to a rural health center with eyelid swelling and localized pain. The patient had a history of irrational amoxicillin use. Limited access to culture testing and guidelines led to empiric ciprofloxacin therapy. The patient demonstrated significant clinical improvement after five days of treatment. There was no disease progression or complications. Discussion: Amoxicillin-clavulanate and cephalosporin remain the preferred treatments for preseptal cellulitis because they provide appropriate coverage against common gram-positive pathogens. Ciprofloxacin is not routinely recommended as monotherapy because of its variable activity against streptococci, potential adverse effects, and risk of promoting antimicrobial resistance. Nevertheless, previous reports have included ciprofloxacin in alternative regimens for patients with severe beta-lactam allergy or limited therapeutic options. In this case, its use represented a context-specific clinical decision based on prior incomplete antibiotic exposure, medication availability, and the absence of microbiological testing. Careful clinical assessment and close monitoring were essential to ensure treatment safety. Conclusion: This case illustrates the potential use of ciprofloxacin as a pragmatic alternative in resource-limited environments where first-line agents are unavailable.
Co-Authors Mustaram, Arief Akhdestira Ohman, Selvania