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All Journal Jurnal Ilmu dan Teknologi Kesehatan Jurnal Abdimas Mahakam Borneo Journal of Pharmacy Media of Health Research
Negara, Yohanes Ardian Kapri
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Humanities Computer Science & IT Dentistry Economics, Econometrics & Finance Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Pencegahan Trichomoniasis melalui Edukasi Kesehatan Organ Kewanitaan dan Pemeriksaan Urin di SMK BIM PPMU Mojosari Charisma, Acivrida Mega; Negara, Yohanes Ardian Kapri; Anwari, Farida
Jurnal Abdimas Mahakam Vol. 8 No. 02 (2024): Juli
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24903/jam.v8i02.2417

Abstract

Gaya hidup perilaku remaja yang kurang  baik dapat berpengaruh terhadap kesehatan terutama kebersihan daerah kewanitaan karena dapat terinfeksi salah satunya Trichomonas vaginalis. Trikomoniasis merupakan infeksi yang disebabkan oleh protozoa Thricomonas vaginalis dan merupakan infeksi menular seksual non-virus paling umum ditemukan diseluruh dunia. Kegiatan ini dilaksanakan bulan Agustus dan sebanyak dua kali. Sampel dari kegiatan ini yaitu siswi SMK BIM PPMU Mojosari sebanyak 15 orang. Adapun metode dalam kegiatan ini yaitu ceramah dan pemeriksaan urine. Hasil kegiatan ini yaitu sebanyak 46,67% responden diikuti oleh berumur 15 tahun; 80% responden memiliki perilaku menjaga kebersihan organ kewanitaan dengan baik; 53,3% responden mengerti cara membasuh organ kewanitaan; 66,67% responden memiliki perilaku menjaga kesehatan organ kewanitaan dengan baik sehingga hasil pemeriksaan urine tidak ditemukan adanya Trichomonas vaginalis sebanyak 100%. Kesimpulan dari kegiatan ini yaitu sebagian besar siswi SMK BIM PPMU memiliki pola hidup dalam menjaga kebesihan dan kesehatan organ kewanitaan dengan baik sehingga dalam tidak ditemukan adanya infeksi parasit tersebut.
Perbedaan Nilai Tekanan Darah Antara Operator Produksi Dengan Petugas Laboratorium Pabrik Spunbond Di Balongbendo Negara, Yohanes Ardian Kapri; Anwari, Farida; Prajawanti, Kadeq Novita; Octifani, Amellya
Media of Health Research Vol. 1 No. 3 (2023): Media of Health Research, December 2023
Publisher : Lembaga Publikasi Ilmiah Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70716/mohr.v1i3.21

Abstract

Employees who work in their jobs must achieve work goals within a certain period of time. The purpose of the study was to determine the difference in blood pressure values and hemoglobin levels between Production Operators and Laboratory Officers of the Spunbond Factory in Balongbendo. Blood pressure measurement used ABN aneroid tensimeter, while hemoglobin level measurement used easy touch GCHB. The type of research used was quantitative observational analytic with a cross sectional approach. Data analysis using Statistical Package for Social Science (SPSS) includes chi square test, paired sample t-test, and independent sample t-test. Independent sample t-test statistical test obtained p-value> 0.05. Indicates that there is no significant difference between systolic and diastolic blood pressure values before and after working Production Operators with Laboratory Officers. The results of measuring the hemoglobin level of Production Operators, obtained an average hemoglobin level of 15.0 mmHg. While the results of measuring the hemoglobin level of Laboratory Officers obtained an average value of 15.4 mmHg. The results of the independent sample t-test statistical test obtained a p-value of 0.280 or p-value> 0.05. That there is no significant difference in hemoglobin levels between Production Operators and Laboratory Officers.
Effect Of Aegle marmelos on IgM And IgG Antibody Titers in Rattus norvegicus Prajawanti, Kadeq Novita; Nurdianto, Arif Rahman; Rahmawati, Novia; Negara, Yohanes Ardian Kapri
jitek Vol 11 No 1 (2023): September 2023
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v11i1.1314

Abstract

Aegle marmelos is a traditional plant with many therapeutic benefits; for example, it is used as an immunomodulatory agent. Literature studies reveal many functional and bioactive compounds, such as alkaloids, phenolics, coumarins, flavonoids, terpenoids, and other antioxidants. Based on its chemical content, Aegle marmelos could be an immunomodulatory agent because it can stimulate the production of antibodies against foreign antigens, increasing IgM and IgG. This study aims to determine the effect of Aegle marmelos filtrate on IgM and IgG titers in Rattus norvergicus induced (sheep red blood cells) SRBC 2%. In this study, 30 rats were divided into five groups: negative control received standard diets, positive control received SRBC 2% injection, P1 received SRBC 2% + Aegle marmelos filtrate 25%, P2 received SRBC 2% + Aegle marmelos filtrate 50%, and P3 received SRBC 2% + Aegle marmelos filtrate 75%. The results showed that administration of Aegle marmelos filtrate could increase IgM titers at the highest dose of 75%, although it was not statistically significant. Meanwhile, Aegle marmelos filtrate does not affect IgG titers in SRBC 2% compared to treatment groups.
Effectiveness of Using Methylene Blue Dyes in Papanicolaou Staining in Cytology of Ascites Fluid Charisma, Acivrida Mega; Permatasari, Melati Indah; Negara, Yohanes Ardian Kapri
jitek Vol 12 No 2 (2025): Maret 2025
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v12i2.1803

Abstract

Papanicolaou staining is routinely used in staining ascitic fluid to identify malignant cells. However, pale nucleus arise as a problem associated with Harris hematoxylin, causing the sample to be hard to see under microscope. Methylene blue can be an alternative stain targeting nucleus in fluid sample. This study aims to evaluate the effectiveness of methylene blue in Papanicolaou staining for the cytology of ascitic fluid. The research uses an experimental approach by preparing four smears from each of 6 ascitic fluid samples obtained from the Laboratory of the Faculty of Medicine, at Airlangga University. The four smears were stained differently, consisting of Papanicolaou staining as control, and methylene blue replacing Harris hematoxylin with concentration of 5%, 10% and 15%. Slides were graded for its morphology with quality scores of 1,2,3 and 4, followed by statistical analysis. Based on the results of the Kruskal-Wallis test, the Sig value was 0.001, which was <0.005, showing difference between control and experimental group. Quality assessment revealed slides stained with 5% methylene blue solution to have clear shape of the cell nucleus, cytoplasm and the shape of the cell compared with slides stained with 10% and 15%. Hence, it can be concluded that 5% methylene blue solution can be used as an alternative solution.
Antidiabetic and TNF-α Lowering Effect of Tagetes erecta Extract in Alloxan-Induced Diabetic Rats Prajawanti, Kadeq Novita; Negara, Yohanes Ardian Kapri; Arianing, Intan Febiola; Junitasari, Fitri
Borneo Journal of Pharmacy Vol. 8 No. 2 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i2.6871

Abstract

Diabetes mellitus is a chronic metabolic disorder characterized by impaired insulin production or action, often leading to pancreatic β-cell dysfunction and apoptosis. Pro-inflammatory cytokines, notably Tumor Necrosis Factor-alpha (TNF-α), play a critical role in the pathogenesis of type 2 diabetes (T2D). While Tagetes erecta (marigold) has demonstrated potential in lowering blood glucose in hyperglycemic conditions, its anti-inflammatory effects in diabetic models remain underexplored. This study aimed to evaluate the antidiabetic and TNF-α lowering effects of T. erecta extract in alloxan-induced diabetic rats. Twenty-five male Wistar rats were divided into a normal control group (n=5) and a diabetic group (n=20) induced by alloxan (blood glucose ≥126 mg/dL). Diabetic rats were then randomized into four treatment subgroups (n=5 each): untreated diabetic control, and diabetic groups treated with T. erecta extract at doses of 25 mg/kg BW, 50 mg/kg BW, or 75 mg/kg BW (administered intraperitoneally). Statistical analysis revealed that T. erecta extract significantly reduced blood glucose levels in alloxan-induced diabetic rats (p <0.05). Furthermore, the highest dose of T. erecta extract (75 mg/kg BW) effectively attenuated elevated TNF-α levels, demonstrating a significant anti-inflammatory effect. In conclusion, this study provides compelling evidence that T. erecta extract exhibits both antidiabetic and anti-inflammatory properties by significantly lowering blood glucose and TNF-α levels in alloxan-induced diabetic rats, particularly at the 75 mg/kg BW dose.
Co-Authors Anwari, Farida Arianing, Intan Febiola Charisma, Acivrida Mega Junitasari, Fitri Novia Rahmawati Nurdianto, Arif Rahman Octifani, Amellya Permatasari, Melati Indah Prajawanti, Kadeq Novita