Rivlan, Muhammad Zaidan Fadhlurrohman
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A Review on Silver Nanoparticles Based Biomaterials for Bone Tissue Engineering and Medical Applications Sari, Nasmi Herlina; Rivlan, Muhammad Zaidan Fadhlurrohman; Suteja, Suteja; Kadriyan, Hamsu; Thiagamani, Sentil Muthu Kumar
Indonesian Journal of Chemistry Vol 24, No 4 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.92830

Abstract

Silver nanoparticles (AgNPs) are being studied extensively as nanostructures for novel and enhanced biomedical applications. Nanoparticles in bone grafts have been shown to speed up fracture healing by providing a finer structure for bone tissue engineering. They are known to have excellent antimicrobial properties due to their high surface-to-volume ratio and small particle size, without affecting the material's mechanical properties. AgNPs' distinct property makes them the preferred filler in a wide range of biomaterials, where they play an important role in enhancing properties. AgNP-containing biomaterials can be easily tailored to meet specific requirements in the development of bone tissue. Adjusting size, shape, composition, and surface charge can enhance their effectiveness in interacting with bone cells, promoting cell attachment, and delivering growth factors. Using AgNP-based biomaterials can help prevent or reduce the formation of biofilms. The utilization of these materials in bone tissue engineering has demonstrated potential in treating musculoskeletal conditions and bone traumas. They are versatile for various applications such as bone implants, scaffolds, wound dressings, and antibiotic delivery systems. This review will cover several special topics, including silver-based biomaterials, toxic properties, morphology and mechanical properties of silver-based biomaterials, and applications of silver-based biomaterials in medical applications.
A Review: Peptide-Based Hydrogels Biomaterials: From Synthesis to Biomedical Applications Sari, Nasmi Herlina; Rivlan, Muhammad Zaidan Fadhlurrohman; Thiagamani, Senthil Muthu Kumar
Journal of Fibers and Polymer Composites Vol. 4 No. 1 (2025): Journal of Fibers and Polymer Composites
Publisher : Green Engineering Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55043/jfpc.v4i1.241

Abstract

Peptide-based hydrogel biomaterials (BHP) have emerged as novel therapeutic platforms for biomedical applications, providing accurate, efficient, and regulated drug delivery. This review examines the design, characterization, production, and biomedical applications of BHP, emphasizing their potential benefits in biomedicine. Advances in peptide synthesis techniques have permitted the creation of hydrogels with customized physicochemical properties to satisfy specific biomedical needs. Furthermore, this review delves into BHPs' biomedical uses, focusing on their role in improving therapeutic responses, allowing for sustained drug release, and reducing tumor growth. BHPs, with their biocompatibility, programmable hydrogel production, and adaptability, constitute a viable technique for addressing the problems of ovarian cancer treatment. This paper gives a thorough summary of current achievements in BHP research, bridging the gap between material development and clinical applications.