Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Journal of Dentistry Indonesia B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah
Rakhmatia, Yunia Dwi
Unknown Affiliation
Dentistry

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
PENGGUNAAN MEMBRAN POLY(LACTIC-CO-GLYCOLIC) ACID (PLGA) YANG DIPERKUAT OLEH NANOSELULOSA UNTUK PROSEDUR GUIDED BONE REGENERATION (GBR) Kurniawati, Nathasya; Rakhmatia, Yunia Dwi; Damayanti, Lisda
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Vol 11, No 1 (2024): Vol 11 No 1, Juni 2024
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v11i1.1542

Abstract

Introduction: Poly (lactic-co-glycolic acid) (PLGA) was developed as a bone regeneration membrane due to its biocompatibility and biodegradability, despite its inherent lack of mechanical strength. One method of enhancing the mechanical strength of PLGA is through its combination with nanocellulose, which possesses high mechanical strength. Nevertheless, nanocellulose exhibits rigidity that renders it challenging to manage in a clinical setting. Aim: The objective of this study was to ascertain the potential of PLGA membranes reinforced by nanocellulose as a bone regeneration material. Method: A review of the literature was conducted through online databases PubMed, Science Direct, SCOPUS, and MDPI for the past 10 years. Result: The results of the search yielded four articles discussing the use of synthetic polymers, particularly PLGA reinforced by nanocellulose as a membrane. Of the four articles identified, two solely addressed the biological properties of the membrane, one solely the mechanical properties, and one reported both. The articles found support the theory regarding the advantages and disadvantages of PLGA and nanocellulose as membranes. Conclusion: The utilisation of PLGA membranes reinforced by nanocellulose merits further investigation, as these membranes demonstrate the potential to satisfy the design criteria for a mechanical barrier membrane in bone regeneration.
Selection of Commercially Available Membrane between Resorbable and Nonresorbable Materials for Guided Bone Regeneration Rakhmatia, Yunia Dwi; Ayukawa, Yasunori; Furuhashi, Akihiro; Koyano, Kiyoshi
Journal of Dentistry Indonesia Vol. 29, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Objective: This study aims to evaluate the commercially available membranes used for treatment in Guided Bone Regeneration (GBR). Methods: Four membranes resorbable and non-resorbable were used and a critical size defect in six-week-old Wistar rats was created for membrane application. Meanwhile, the defect without membrane treatment was used as the control (C). Results: After 4 and 8 weeks, all rats were euthanized and block biopsies of calvaria including membrane were excised and analysed using microcomputed tomography (micro-CT). The sections were dehydrated with graded ethanol, embedded in resin, and cut for histologic evaluation. After 4 weeks, all membrane groups and the control showed different degrees of bone volume (BV) and mineral density (BMD). Titanium mesh (TM) was observed with higher bone volume but lower BMD compared to the control, Cytoplast (CP), Biomend (BM), and GC membranes. The results showed that newly formed bone adjacent to the original filled the defect area. Conclusion: TM was the stiffest among the commercially available membranes used and increased the abundance of bone formation at 4 weeks. The selection of membranes used in GBR needs to consider the treatment requirement and the patient’s point of view.
Co-Authors Ayukawa, Yasunori Furuhashi, Akihiro Koyano, Kiyoshi Kurniawati, Nathasya Lisda Damayanti