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All Journal International Journal of Health, Engineering and Technology Jurnal Indah Sains dan Klinis
Ruth Mayana Rumanti
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Potensi Antibakteri Kombinan Zingiber officinale var. Rubrum dengan Cinnamomum burmannii terhadap Staphylococcus aureus Ruth Mayana Rumanti; Suprianto; Jakub Tarigan; Arinri Misnangin Sritala Ramadani
Jurnal Indah Sains dan Klinis Vol 2 No 1 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.8

Abstract

Red Ginger (Zingiber officinalevar. Rubrum) and Cinnamon (Cinnamomum burmannii) contain alkaloids, flavonoids, saponins, tannins, triterpenoids and essential oils. which is antibacterial that causes pharyngitis by Staphylococcus aureus. This study aims to determine the antibacterial potency of the combination of Red Ginger (Zingiberofficinalevar. Rubrum) and Cinnamon (Cinnamomum burmannii) extract against Staphylococcus aureus. Experimental research includes the extraction of the compound components in red ginger and cinnamon by maceration with 70% ethanol. Inhibition was tested bydiffusion method. Combination of concentration of Red Ginger and Cinnamon extracts of 5%:40%; 10%:30%; 20%:20%; 30%:10% and 40%:5%. The combination of red ginger and cinnamon extract has antibacterial activity against pharyngitis-causing bacteria, namely Staphylococcus aureuswith a strong response at a concentration of 5%:40%
Identification Of Flavonoid Compounds and Antioxidant Activity Test of Ethyl Acetate Extract of Matoa Leaves (Pometia Pinnata) Using the Dpph Method Rika Puspita Sari; Ruth Mayana Rumanti; Dian Ning Fathta
International Journal of Health Engineering and Technology Vol. 4 No. 4 (2025): IJHET NOVEMBER 2025
Publisher : CV. AFDIFAL MAJU BERKAH

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Abstract

This research aimed to identify the flavonoid compoxunds and test the antioxidant activity of the ethyl acetate extract of matoa leaves (Pometia pinnata). The extraction was performed xusing the maceration method with ethyl acetate as the solvent. Phytochemical screening was condxucted to determine the groxups of secondary metabolites, while specific identification of flavonoids was carried oxut xusing Thin Layer Chromatography (TLC). The antioxidant activity was tested xusing the DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging method, measxured with a XUV-Vis spectrophotometer to determine the Inhibitory Concentration 50 (IC50) valxue. The phytochemical screening resxults indicated that the extract positively contained alkaloids, flavonoids, tannins, saponins, and triterpenoids. The TLC test also confirmed the presence of flavonoid compoxunds. The antioxidant test resxults showed that the ethyl acetate extract of matoa leaves possesses strong antioxidant activity with an IC50 valxue of 72.32 µg/mL. This valxue indicates that the matoa leaf extract has the potential to be developed as a soxurce of natxural antioxidants.
Co-Authors Arinri Misnangin Sritala Ramadani Dian Ning Fathta Jakub Tarigan Rika Puspita Sari Suprianto Suprianto