Pazka, Khoirunnisa Sarabayan
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The Analysis Study Of Chronic Kidney Disease After Acute Kidney Injury: A Comprehensive Systematic Review Wirawan, Nugraha; Pazka, Khoirunnisa Sarabayan
The International Journal of Medical Science and Health Research Vol. 2 No. 1 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: The relationship between Acute kidney injury (AKI) and CKD is complex, with chronic kidney disease (CKD) being a risk factor due to reduced renal reserve and stress-related issues. AKI can initiate or accelerate CKD development, leading to maladaptive repair mechanisms and a growing public health burden. This systematic review aims to analyze current evidence on the risk of CKD development after AKI based on literatures of the last 10 years. Methods: The study adhered to PRISMA 2020 standards, examining English literature from 2014 to 2024. It excluded editorials, reviews from the same journal, and submissions without a DOI. PubMed, SagePub, SpringerLink, and Google Scholar were utilized as literature sources. Result: Initially retrieving 360 articles from online databases (PubMed, SagePub, SpringerLink and Google Scholar) eight relevant papers were selected after three rounds of screening for full-text analysis. Conclusion: Acute kidney injury (AKI) is a precursor to chronic kidney disease (CKD), impacting long-term renal health. Even mild episodes contribute to sustained glomerular filtration rate reductions, suggesting incomplete recovery and a narrow intervention window for prevention.