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All Journal International Journal of Scientific Multidisciplinary Research (IJSMR)
Suherman Baharuddin
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Decision Sciences, Operations Research & Management Education Law, Crime, Criminology & Criminal Justice Mechanical Engineering Social Sciences

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Potential of Purple Sweet Potato (Ipomoea batatas var. Ayamurasaki) Skin Extract Cream Preparation as an Antibacterial Against the Growth Activity of Propionibacterium acnes Andi Indrawati; Suherman Baharuddin
International Journal of Scientific Multidisciplinary Research Vol. 1 No. 10 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijsmr.v1i10.6765

Abstract

This study aims to determine the potential of a purple sweet potato (Ipomoea batatas var. Ayamurasaki) skin extract cream preparation on the growth activity of Propionibacterium acnes and determine the most effective concentration of the cream preparation. This type of research is experimental, namely laboratory research. Extraction process sample deusing the maceration method, the extract is made in the form of a cream dosage, next the growth activity of Propionibacterium acnes was tested. The research results show that cream preparations purple sweet potato (Ipomoea batatas var. Ayamurasaki) skin extract potentially hindering growth of Propionibacterium acnes, and the concentration of the cream preparation that is most effective in inhibiting growth Propionibacterium acnes is a concentration of 3% (FIV) with a Sig value. 0.000<0.05 (Oneway Anova α=0.05) in bacterial inhibition in the strong category (10–20 mm)
Profile of Multi Drug Resistant Tuberculosis (MDR-TB) Patients Using Anti-TB Drugs in the Outpatient Unit of RSUD Poso Year 2022 Ajeng Kurniati Roddu; Suherman Baharuddin; Nur Aini Amir
International Journal of Scientific Multidisciplinary Research Vol. 2 No. 7 (2024): July 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijsmr.v2i7.10382

Abstract

The purpose of this study was to determine and further examine the description of Multi Drug Resistant Tuberculosis (MDR-TB) patients who have used anti-tuberculosis drugs in the Poso Regional General Hospital outpatient unit. This type of research is a non-experimental descriptive study (retrospective in nature) using research instruments in the form of data collection (prescriptions or medical records) of outpatient MDR-TB patients at the Poso Regional General Hospital, Central Sulawesi in 2022. Based on the results of research that has been conducted in the period January - December 2022, it can be concluded that the characteristics of treatment in Tuberculosis patients as a whole are 226 people, there are patients with MDR-TB drugs 16 people (7.08%), with a total of 127 prescription sheets (11.28%), the potential for drug interactions 36 prescriptions (28.35%) and no interactions 91 prescriptions (71.65%). Types of opportunistic infections are with a history of diabetes mellitus (DM) 6 people (37.50%), comorbid kidney and liver disease 2 people (12.50%), HIV-AIDS disease 2 people (12.50%), pneumonia 5 people (31.25%), fungal infection 1 person (6.25%). The average use of MDR-TB drugs with more than 1 type of drug will produce drug side effects on initial therapy and continued therapy with a total of 14 cases (87.50%) with different drug side effects and 2 people (12.50%) who did not experience drug side effects
Antibacterial Potential of Agarwood Leaf Extract (Aguilaria Microcarpa Baill) Against Salmonella Typhi Andi Indrawati; Suherman Baharuddin; Dewi Isnaeni
International Journal of Scientific Multidisciplinary Research Vol. 2 No. 8 (2024): August 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijsmr.v2i8.10725

Abstract

Aguilaria microcarpa Baill, commonly known as the Agarwood plant, is commonly used as a medicinal plant that is thought to be able to treat certain diseases because it contains chemical compounds in the form of alkaloids, flavonoids, glycosides, and tannins which can act as antioxidants and antibacterials and can be used as raw materials for the medicinal industry natural herbs. Testing in this research nature is semi-quantitative and is laboratory research in testing Aguilaria microcarpa Baill leaf extract based on characterization tests, chemical content tests, and antibacterial potential tests on growth activity of Salmonella typhi with inhibition zone parameters produced by the agar diffusion method. The results showed that Agarwood leaf extract (Aguilaria microcarpa Baill) with concentrations of 3%, 6%, 9%, and 12% w/v had the potential as an antibacterial against growth activity Salmonella thypi. The higher the concentration of the extract tested, the greater the inhibitory activity against bacterial growth. The most effective concentration is at a concentration of 12% w/v with a Sig value. 0.000 < 0.05   (Oneway Anova α = 0.05) in strong category inhibition ( 10 – 20 mm)
Co-Authors Ajeng Kurniati Roddu Andi Indrawati Dewi Isnaeni Nur Aini Amir