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All Journal JPSCR : Journal of Pharmaceutical Science and Clinical Research Indonesian Journal of Medical and Pharmaceutical Science
Purnami, Islina Dewi
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Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Hubungan Tingkat Pendidikan Serta Usia Terhadap Pengetahuan Penggunaan Obat Analgesik dan Antipiretik pada Ibu Hamil di Puskesmas Gayamsari Purnami, Islina Dewi; Ulfa, Yulinda Aini
Indonesian Journal of Medical and Pharmaceutical Science Vol. 3 No. 2 (2024)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v3i2.174

Abstract

Background: Pain during pregnancy needs to be handled properly because pain that affects physically and psychologically pregnant women can cause depression and anxiety. Analgesic drugs are the most commonly given drugs worldwide and most analgesics are sold freely so do not require a prescription. The aim of this study was to determine the effect of education level and age on knowledge and consumption of analgesic and antipyretic drugs in pregnant women to reduce the risks posed during pregnancy and lactation. Methods: The study was conducted cross-sectionally at the Gayamsari Health Center in Semarang City. The sampling method used is purposive sampling. The instrument used is a questionnaire consisting of a knowledge questionnaire and a questionnaire on the use of analgesic and antipyretic drugs in pregnant women. The study sample was pregnant women who came and visited the Gayamsari Health Center and met the inclusion criteria. Results: The level of knowledge of pregnant women regarding analgesic and antipyretic drugs consumed during pregnancy is in the “High” category with a percentage of 80.0% and the results of the use of analgesic and antipyretic drugs in pregnant women show that respondents already understand well. Conclusion: Age did not affect the level of knowledge of pregnant women about analgesic and antipyretic drugs with a p-value of 0.216 where the p-value was greater than the significance level (α=5%). Correlation analysis also found that there was no significant relationship between recent education and the level of knowledge of pregnant women (p = 0.981 > 0.05).
Perbandingan Efektivitas Terapi Akupuntur dengan NSAID Terhadap Nyeri Low Back Pain (LBP) Pasien Rawat Inap di Rumah Rakit RSD KRMT Wongsonegoro Semarang Purnami, Islina Dewi; Kamal, Siti Habibah
Indonesian Journal of Medical and Pharmaceutical Science Vol. 4 No. 2 (2025)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v4i2.439

Abstract

ABSTRACT Background: Low Back Pain (LBP) is among the most prevalent musculoskeletal disorders, often resulting in functional limitations and reduced quality of life. The condition may originate from spinal structures, muscles, nerves, or adjacent tissues. Acupuncture, a traditional therapy involving the insertion of fine needles at specific points, represents one non-pharmacological treatment option. For LBP, the commonly targeted points include Shensu (BL 23), Dachangshu (BL 25), and Weizhong (BL 40) bilaterally to alleviate pain. The objective of this study is to compare the therapeutic effectiveness of acupuncture with nonsteroidal anti-inflammatory drugs (NSAIDs) in alleviating pain and improving functional outcomes in patients with LBP. Methods: This retrospective study compared the effectiveness of acupuncture and pharmacological therapy with NSAIDs in LBP patients at Wongsonegoro Hospital, Semarang. Medical records of 70 purposively selected patients were reviewed based on age, nonspecific LBP diagnosis, willingness to undergo therapy, and provision of informed consent. Acupuncture was administered four times at one-week intervals over a two-month period. Results: Acupuncture at BL 23, BL 25, and BL 40 demonstrated significant pain reduction. Wilcoxon test analysis yielded a significance level of 0.000 in both groups. In the NSAID group, 35 respondents experienced clinically meaningful improvement, whereas the acupuncture group showed a mean rank of 18.00, underscoring its effectiveness. Conclusion: Both NSAIDs and acupuncture were effective in reducing pain among LBP patients. Thibbun Nabawi acupuncture may be considered as a first-line or adjunctive therapy, particularly in patients with contraindications to NSAIDs or those opting for non-pharmacological interventions. Keywords: acupuncture; NSAID; LBP
The Effect of Halal Labelling of Medicine on Customer’s Purchase Interest at Karunia Sehat Baru Pharmaceutical Semarang Purnami, Islina Dewi; Sawitri, Agustina; Ummaya, Ulfa Ulli
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 2 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i2.86

Abstract

Background: Halal labeling is the inclusion of halal writing or statements on product packaging to indicate that the product in question has the status of a halal product. The purpose of this study was to determine the effect of halal labeling on drugs on customer buying interest at the Karunia Sehat pharmacy in Semarang. Methods: The population in this study were all customers who came to the gift health pharmacy, and the number of samples needed was 96 respondents. Data was collected by distributing questionnaires directly to customers using a linkert scale and then scoring. Results: Based on data analysis, halal labeling on medicinal products are "very influential" on customer buying interest with a percentage of 71.9% which is in the 41-50 score category. Conclusion: halal labeling on medicinal can affect on customer’s purchase interest at Karunia Sehat Baru Pharmaceutical Semarang.
Analisis Efektivitas Biaya Terapi Enoxaparin dan Fondaparinux Pada Pasien Jantung N-STEMI Rawat Inap di RSD K.R.M.T. Wongsonegoro Purnami, Islina Dewi; Nugrahaeni, Atma Rulin Dewi; Khasanah, Ulfatun
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.114

Abstract

Background: N-STEMI heart disease in the community can provide a significant health and economic burden so that it can affect the quality of patient health. Enoxaparin and fondaparinux are often given to inpatients to overcome this problem because of the consideration between efficacy and safety of using drugs, one of which is the risk of patient bleeding. This study aim to determine the cost effectiveness of enoxaparin therapy and fondaparinux in the treatment of N-STEMI cardiac patients at RSD K.R.M.T. Wongsonegoro. Methods: This study is a descriptive observational method using a retrospective data collection from secondary data from the patient's medical record and the cost of care and treatment of patients during hospitalization. Processing of data in the form of numbers using Microsoft Excel then the data is processed according to the ACER and ICER calculation formulas. Results: The results show that compared to enoxaparin, fondaparinux is a cost-saving strategy (lower cost with slightly higher effectiveness). Fondaparinux is the most cost effective treatment for N-STEMI heart patients at RSD K.R.M.T. Wongsonegoro. Conclusion: Fondaparinux should be considered as a cost-effective alternative when compared to enoxaparin for inpatient N-STEMI cardiac patients at RSD K.R.M.T. Wongsonegoro based on length of hospitalization and duration of therapy, especially in the era of limited health resources.
Penerapan Penggunaan Antibiotik Bersertifikasi Halal Pada Pasien Anak Dengan Diare Akut Di RSD K.R.M.T Wongsonegoro Purnami, Islina Dewi; Nugrahaeini, Atma Rulin Dewi; Aprilla, Trifani
Indonesian Journal of Medical and Pharmaceutical Science Vol. 2 No. 1 (2023)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v2i1.121

Abstract

Background : The use of antibiotics in accordance with the antibiotic resistance control program in pediatric patients with acute diarrhea and halal  certification on antibiotics. The purpose of this study was to known the implementation of halal certification antibiotics according to antibiotic resistance control program in pediatric patients with acute diarrhea at RSD K.R.M.T Wongsonegoro. Methods: The research method used was a retrospective descriptive approach by collecting data from medical records in pediatric patients with acut diarrhea. The population in this study were pediatric patients with acute diarrhea who were hospitalzed at RSD K.R.M.T Wongsonegoro, with inclusion criteria being pediatric patients diagnosed with acute diarrhea in inpatient care. Data taken from medical records include: age, gender, name of antibiotik, route of administration, then the use of antibiotic is calculated by the DDD (Defined Daily Dose/100 patient-days) formula, for halal certification of antibiotics through the MUI website  then calculate the percentage. Results: the number of  antibiotic used  in the treatment of acute diarrhea in children 36 pediatric patients ware ceftriaxone antibiotic as much as 24.57, Cefotaxime  5.47, oral  metronidazole 4.52,   amoxicillin 1.31, parenteral metronidazole 1.27 and  0,1 cefixme either orally or parenterally. While the percentage of antibiotics that have halal certification is 100%. Conclusion: Antibiotic with the highest use was cefotaxime 5.57 while the lowest was cefixime 0.1. for all antibiotics in the RSD K.R.M.T Wongsonegoro, they have been certified halal.   Keywords: Acute Diarrhea; Antibiotic; Halal Certification; Pediatric Patient; Resistance
Pengaruh Pemberian Obat Asam Folat, Eritropoietin dan Kombinasi Asam Folat Eritropoietin dalam Meningkatkan Hemoglobin pada Pasien Hemodialisa di RSUD dr. Gunawan Mangunkusumo Purnami, Islina Dewi; Indriani, Yonanda Pratiwi; Susilowati, Dwi Retna
Indonesian Journal of Medical and Pharmaceutical Science Vol. 3 No. 1 (2024)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v3i1.136

Abstract

Background: Anemia is a decrease in the total amount of hemoglobin or the number of red blood cells which causes insufficient oxygen supply to meet the body's physiological needs. This study aim to determine the effect of administration of folic acid, erythropoietin (hemapo) and erythropoietin folic acid combinations in increasing hb in hemodialysis patients at RSUD dr. Gunawan Mangunkusumo. Methods: This research is a non-experimental study using a cross-sectional design. Data collection was carried out retrospectively using medical records taken at the medical record unit which received treatment therapy with folic acid, erythropoietin and erythropoietin folate combination in outpatient hemodialysis patients. The sampling technique was carried out by purposive sampling technique. Data obtained during the study were analyzed using the Paired T-test (p-Value = <0.05). Results: Based on the Paired T-Test analysis, it is known that the p-Value = 0.001, this indicates that there is a significant difference in changes in hemoglobin levels before and after consuming folic acid, erythropoietin (hemapo), and the combination of increased Hb in hemodialysis patients at RSUD dr. Gunawan Mangunkusumo. Conclusion: The results of research that has been conducted usingOthe Paired T-Test show that there is a significant difference in changes in hemoglobin levels before and after consuming folic acid, erythropoietin (hemapo), and the combination in increasing Hb in patients at RSUD dr. Gunawan Mangunkusumo.
Hubungan Pengetahuan Tenaga Kesehatan Tentang Pharmacovigilance Terhadap Sikap Pelaporan ADR di Kota Semarang Sabiti, Farroh Bintang; Purnami, Islina Dewi; Arief, Thendi Abdul; Sofa, Nada Aini; Yanto, Andre; Permatasari, Juliantika Diah
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 8, No 2 (2023)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v8i2.68202

Abstract

Adverse Drug Reaction (ADR) merupakan efek samping obat yang tidak diinginkan atau respon dari suatu obat yang merugikan. ADR yang tidak dilaporkan dapat menjadi masalah utama, sehingga sangat diperlukan untuk meningkatkan kualitas dan kuantitas pelaporan. Kurangnya pelaporan ADR oleh tenaga kesehatan dapat dipengaruhi oleh beberapa faktor termasuk pengetahuan dan sikap. Penelitian terkait pengetahuan pharmacovigilance pada tenaga kesehatan terhadap sikap pelaporan ADR khususnya di Rumah Sakit dan Puskesmas tidak ada, sehingga tidak diketahui bagaimana pengetahuan pharmacovigilance terhadap sikap ADR pada tenaga kesehatan di kota Semarang. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan pharmacovigilance terhadap sikap pelaporan ADR pada tenaga kesehatan di Rumah Sakit dan Puskesmas. Jenis penelitian ini adalah deksriptif analitik dengan rancangan cross sectional. Populasi dan sampel dalam penelitian ini adalah 84 tenaga kesehatan (Dokter, Apoteker, dan Perawat) di Rumah Sakit dan Puskesmas. Pengumpulan data menggunakan kuesioner yang mencakup 20 pertanyaan. Instrumen berupa KAP yang dirancang untuk menilai rincian demografi tenaga kesehatan, pengetahuan dan sikap terkait pharmacovigilance. Analisis data menggunakan Fisher’s Exact Test karena tidak memenuhi syarat uji Chi-Square. Hasil penelitian menunjukkan responden terbanyak dengan kategori pengetahuan baik sebanyak 46 responden dengan persentase 54.76%, sedangkan responden yang memiliki pengetahuan cukup sebanyak 38 responden dengan persentase 45.24%. Hasil penilaian sikap tenaga kesehatan dalam pelaporan ADR meliputi kategori cukup sebanyak 54 responden dengan persentase 64.29% dan kategori baik sebanyak 30 responden dengan persentase 35.71%. Hubungan pengetahuan pharmacovigilance pada tenaga kesehatan terhadap sikap pelaporan ADR memiliki hubungan yang signifikan dengana nilai p = 0.013 (p < 0.05).
Co-Authors Aprilla, Trifani Arief, Thendi Abdul Indriani, Yonanda Pratiwi Kamal, Siti Habibah Khasanah, Ulfatun Nugrahaeini, Atma Rulin Dewi Nugrahaeni, Atma Rulin Dewi Permatasari, Juliantika Diah Sabiti, Farroh Bintang Sawitri, Agustina Sofa, Nada Aini Susilowati, Dwi Retna Ulfa, Yulinda Aini Ummaya, Ulfa Ulli Yanto, Andre