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Management of Stage-4 HIV with Cerebral Toxoplasmosis Coinfection and SIADH Complication Laksono, Pandu; Oktavia, Erlin; Putri, Hidayati Adi; Herawati, Fauna
Majalah Kedokteran Bandung Vol 56, No 3 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3355

Abstract

HIV/AIDS stage 4 is the stage where the HIV/AIDS patients have low immunity protection against infections, which can led to coinfections and complications. This case report presented an evaluation of the diagnosis and treatment of an HIV/AIDS stage 4 patient with cerebral toxoplasmosis coinfection and SIADH complications. A man (47 years, 35 kg), married with two children, complaining of weakness, nausea, vomiting, weight loss, and low appetite. Sodium level were measured, showing a 117 mg/dL level that continued to decrease throughout the patient's treatment. Five days later, the patient lost his consciousness with a GCS score of 224, indicating severe brain injury, and was diagnosed with cerebral toxoplasmosis based on the result of head CT-SCAN with contrast. On day 6, the patient was tested positive for HIV and diagnosed with stage 4 with an absolute CD4 count of 4 cells/μl. Therapy was provided by giving pyrimethamine-clindamycin therapy for cerebral toxoplasmosis, followed by Tenofovir, Lamivudine, and Evafirenz as antiretroviral therapy. Treatment for hyponatremia was done by administration of 3% NaCl and tolvaptan. The patient started experiencing an improvement in consciousness after the 10th day of medication, and sodium levels fluctuated throughout the treatments. Patient was discharged after 15 days with clinical improvements.
Efisiensi Digital Marketing Dalam Meningkatkan Penjualan Produksi Home Industry Malessa Fashion dan Craft di Kota Surakarta Oktavia, Erlin; Purnomo, Didit
Determinasi: Jurnal Penelitian Ekonomi Manajemen dan Akuntansi Vol. 4 No. 1 (2026)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/determinasi.v4i1.589

Abstract

This research aims to analyze the efficiency of digital marketing in increasing sales in the home industry of Malessa Fashion and Craft in Surakarta City. The research uses qualitative methods with data collection through interviews, observations, and direct experiences during the Merdeka Entrepreneur Internship program. The research results show that the implementation of digital marketing strategies through WhatsApp Business, Instagram, and Facebook platforms significantly increases sales. Special features such as business profiles, automated messages, feeds, stories, and direct interactions with customers have proven effective in expanding market reach, increasing audience engagement, and building customer trust. However, increasing audience engagement on Instagram still faces challenges due to the platform's algorithm and the quality of the uploaded content. Overall, digital marketing has become an effective solution for home-based industries to face increasingly tight and dynamic market competition.