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All Journal Majalah Kedokteran Bandung Jurnal Medika Malahayati
Sugiarti, Emmy Dwi
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Ocular Manifestation In Marfan Syndrome: A Case Report Wicaksana, Muhammad Akbar; Sugiarti, Emmy Dwi
Jurnal Medika Malahayati Vol 8, No 3 (2024): Volume 8 Nomor 3
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v8i3.14525

Abstract

Sindrom Marfan adalah gangguan kongenital autosomal dominan yang memengaruhi jaringan ikat dalam beberapa sistem. Kelainan pada protein fibrilin-1 dapat menyebabkan kelainan dalam beberapa sistem. Tujuan laporan ini adalah untuk mendokumentasikan manifestasi klinis pada pasien sistem okular dan tatalaksana pasien dengan sindroma marfan. Seorang pria berusia 26 tahun datang ke Rumah Sakit Mata Cicendo, dirujuk dari Unit Kardiologi di Rumah Sakit Hasan Sadikin, dengan keluhan utama penglihatan kabur sejak sekolah dasar. Saat pemeriksaan fisik, subluksasi lensa teramati di kedua mata terutama saat dilatasi pupil. Evaluasi biometrik mengungkapkan kornea yang relatif datar dengan panjang aksial yang panjang. Tajam penglihatan pasien membaik dengan kacamata. Pasien diberikan kacamata dan diberi edukasi tentang sifat progresif penyakit dan risiko pewarisan penyakit. Tidak semua pasien dengan sindrom Marfan yang mengalami gejala okular memerlukan intervensi bedah. Terapi non-bedah dapat membantu pasien mencapai ketajaman visual yang layak. Evaluasi sistemik dapat membantu pasien memahami dan mitigasi penyakit.
Comparison of Phaco-Chop versus Stop-and-Chop Nucletomy Techniques in Patients with Soft to Moderate Nucleus Cataracts Budiman, Budiman; Knoch, Andrew M. H.; Sugiarti, Emmy Dwi; Tjokrovonco, Ludwig Melino
Majalah Kedokteran Bandung Vol 56, No 2 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3184

Abstract

Various phacoemulsification techniques are commonly used, with phaco-chop and stop-and-chop techniques as the most popular ones. Phacoemulsification inevitably leads to endothelial cell destruction, which, in severe cases, might result in vision impairment. This study aimed to compare endothelial cell characteristics between two phacoemulsification procedures, phaco-chop, and stop-and-chop, in patients with soft to moderate nucleus cataracts. This study was conducted on 142 patients at the National Eye Center of Cicendo Hospital between April and August 2018. Of those, 66 patients underwent the phaco-chop technique, while 76 patients underwent the stop-and-chop technique. Intraoperative parameters such as effective phaco time (EPT), phaco time, average power, and duration were recorded. Endothelial density, hexagonality, coefficient of variation (CV), and central cornea thickness (CCT) were also recorded before surgery, as well as one week and four weeks after surgery. Mean power, EPT, phaco time, and duration in the phaco-chop group were significantly lower than in the stop-and-chop group. Mean (SD) endothelial density at one-week and four-week evaluation in the phaco-chop group were considerably lower than in the stop-and-chop group (p-value=0.024 and p-value=0.000, respectively). Mean (SD) CV at one-week evaluation in the phaco-chop group was significantly higher compared to a stop-and-chop group, 43.3 (8.0) versus 40.0 (6.7) % (p-value=0.009). Mean (SD) hexagonality at four-week evaluation in the phaco-chop group was significantly higher compared to a stop-and-chop group (43.1 (17.6) versus 48.7 (13.2) respectively, p-value=0.045). Phaco-chop technique have significantly lower EPT, average power, phaco time, and surgery duration than stop-and-chop techniques at one-week and four-week evaluation after phacoemulsification.
Co-Authors Budiman Budiman Knoch, Andrew M. H. Tjokrovonco, Ludwig Melino Wicaksana, Muhammad Akbar