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All Journal Pharmaceutical Sciences and Research (PSR) Pharmacology And Pharmacy Scientific Journals (PAPS Journals)
Anjani, Qonita Kurnia
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Medicine & Pharmacology

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Solid Lipid Nanoparticles (SLN): Formulation and Fabrication Punu, Gabriella F.; Harahap, Yahdiana; Anjani, Qonita Kurnia; Hartrianti, Pietradewi; Donnelly, Ryan F.; Ramadon, Delly
Pharmaceutical Sciences and Research Vol. 10, No. 2
Publisher : UI Scholars Hub

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Abstract

Solid lipid nanoparticles (SLN) have emerged as a novel drug delivery system and have been utilized for delivering various kinds of drugs since the 1990s. These particles may consist of multiple solid lipids, including glycerides, waxes, and fatty acids, and can be stabilized by a wide range of surfactants. SLN have garnered significant attention from researchers due to its innovative and versatile nature. Moreover, such delivery system has numerous advantages over traditional colloidal carriers, such as liposomes, polymeric nanoparticles, and emulsions. Several research groups have been developing SLN formulations and fabrication techniques based on their intended purpose, and this research number is still increasing globally. Given the vast potential for the development of SLN in the future, coupled with the wide variety of materials and techniques to be considered during the manufacturing process, this paper provides an extensive overview of the general introduction of SLN, their benefits and drawbacks, and the numerous excipients which can be associated with the SLN formulation. Various aspects related to the models of drug incorporation and fabrication methods are also systematically discussed in this review. In addition, an analysis of the factors that impact the stability of the SLN will also be documented to provide further insight for future advancements in SLN research.
IMPLEMENTASI PENGGUNAAN METODE ECONOMIC ORDER QUANTITY DALAM PENCEGAHAN SEDIAAN OBAT EXPIRED DI DINAS KESEHATAN KABUPATEN PASANGKAYU Fadhilah, Nur; Jangga, Jangga; Anjani, Qonita Kurnia
Pharmacology And Pharmacy Scientific Journals Vol. 3 No. 2: Desember, 2024, PAPS
Publisher : Unit Publikasi Ilmiah Perkumpulan Intelektual Madani Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51577/papsjournals.v3i2.683

Abstract

Pengendalian bertujuan untuk memastikan pencapaian tujuan yang telah direncanakan. Pengendalian bukan hanya untuk mendeteksi kesalahan, tetapi juga untuk mencegah dan memperbaikinya jika terjadi. Proses pengujian dilakukan sebelum, selama, dan setelah pelaksanaan kegiatan, hingga hasil akhir tercapai. Dengan adanya kontrol, diharapkan unit kontrol dapat digunakan secara efisien, dan kegiatan manajerial yang efektif dalam perusahaan dikenal sebagai pengendalian internal. Tujuan dari penelitian ini yaitu Untuk mengetahui pengendalian jumlah pemesanan optimum obat, meminimalkan obat Expayer Date, dan mengetahui buffer stock dan reorder point (ROP). Hasil penelitian ini menunjukkan bahwa pengendalian/pengawasan persediaan obat melalui stock opname, kartu stok, buku defekta dan laporan bulanan dengan jumlah pemesanan optimum obat AMLODIPIN yaitu 16.490 strip obat setiap kali pesan, dilakukan pemesanan kembali ketika stok obat sudah mencapai 8.747 strip agar bisa meminimalkan obat expired, Buffer stock atau safety stock pada obat AMLODIPIN yaitu 5.879 strip, dan Reorder Point (ROP) obat AMLODIPN yaitu 8.747 pada instalasi farmasi Dinas Kesehatan Kabupaten Pasangkayu.
Co-Authors Donnelly, Ryan F. Hartrianti, Pietradewi Jangga Nur Fadhilah Punu, Gabriella F. RAMADON, DELLY Yahdiana Harahap