Yani Ambari
Universitas Anwar Medika

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

Pengaruh Variasi Konsentrasi Manitol-Sukrosa Sebagai Bahan Pengisi Pada Formulasi Tablet Hisap Terhadap Sifat Fisik Sediaan Salsabilla Dhiya Atik Nuraini; Fitria Ayu Kusumaningtyas; Rahma Dwi Novitasari; Abdullah Syafiq Ahmadi; Nandiyyah Atikah; Shabrina Putri Arianti; Dewi Rahmawati; Yani Ambari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i4.451

Abstract

This article discusses the effect of variations in the concentration of mannitol-sucrose as a filler in the formulation of antioxidant lozenges from various plant extracts on the physical properties of the preparation. Lozenges are preparations that can contain active substances with additional ingredients and sweeteners that dissolve in the mouth. The use of mannitol and sucrose as additional ingredients in lozenges provides advantages such as sweet taste and ease of use. The aim of this study is to find the optimal ratio between mannitol and sucrose to obtain good physical properties of lozenges. The research method used is a literature review article (LRA) by accessing information sources from databases such as Google Scholar and PubMed. The results showed that variations in mannitol-sucrose concentration affected the physical properties of lozenges, such as weight uniformity, hardness, friability, and tablet disintegration time. Thus, choosing the right ratio between mannitol and sucrose is important to produce quality lozenges.
Review Artikel: Formulasi Tablet Menggunakan Metode Granulasi Basah Ni’matul Fauziah; Miftahul Maulidiyah; Silvia Nur Diana Putri; Heni Amilia Putri; Ferdiana Putri Veronica; Anisya’ Khusnul Khotimah; Renny Anggrayni; Dewi Rahmawati; Yani Ambari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i4.535

Abstract

Tablets are one of the most commonly used solid dosage forms of medicine in the pharmaceutical industry. The granulation process commonly used in making tablets is the wet granulation process. The operation method includes mixing the active ingredients and excipients, adding a binder liquid, forming granules, drying and sieving. The methods used in this research are literature research, journal reviews, and analysis of relevant papers carried out during the 2015-2023 period. The aim of this literature study is to determine the process, advantages, limitations and application of wet granulation in the pharmaceutical industry. Based on the results of a literature study, tablet production using the wet granulation method was proven to be an effective technique and is widely used for the production of tablet formulations.
Artikel Review: Pengaruh Variasi Konsentrasi Bahan Pengikat Pada Formulasi Tablet Salut Serta Karakteristik Terhadap Sifat Fisik Sediaan Marcelinda Krisdivayanti; Icasia Carolina Dewi; Laila Sabila Sindriyani; Ana Fatmah Azzahro; Nabyla Qutrun Nada; Alfan Hermawan; Dewi Rahmawati; Yani Ambari; Marthy Meliana Ariyanti Jalmav; Muhammad Fithrul Mubarak
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i4.559

Abstract

Coated tablets are compressed tablets that are coated with a mixture of various substances such as: resin, gum, fillers, sugar, plasticizers, polyols, coloring agents, and flavor enhancers in the active substance. The types of coated tablets that are developing are sugar-coated, thin-coated and enteric-coated tablets. One of the additional materials that plays an important role in making coated tablets is a binder. This review article aims to obtain information and examine what is a good concentration of binder to use in coated tablet formulations. Based on a literature study from several articles collected, it can be concluded that the lactose binder, porang tuber starch, and PVP in several coated tablet dosage formulations, these binders have no effect on the physical properties of the dosage form.