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Nandiyyah Atikah
Universitas Anwar Medika
Health Professions Nursing Public Health

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Pengaruh Variasi Konsentrasi Manitol-Sukrosa Sebagai Bahan Pengisi Pada Formulasi Tablet Hisap Terhadap Sifat Fisik Sediaan Salsabilla Dhiya Atik Nuraini; Fitria Ayu Kusumaningtyas; Rahma Dwi Novitasari; Abdullah Syafiq Ahmadi; Nandiyyah Atikah; Shabrina Putri Arianti; Dewi Rahmawati; Yani Ambari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i4.451

Abstract

This article discusses the effect of variations in the concentration of mannitol-sucrose as a filler in the formulation of antioxidant lozenges from various plant extracts on the physical properties of the preparation. Lozenges are preparations that can contain active substances with additional ingredients and sweeteners that dissolve in the mouth. The use of mannitol and sucrose as additional ingredients in lozenges provides advantages such as sweet taste and ease of use. The aim of this study is to find the optimal ratio between mannitol and sucrose to obtain good physical properties of lozenges. The research method used is a literature review article (LRA) by accessing information sources from databases such as Google Scholar and PubMed. The results showed that variations in mannitol-sucrose concentration affected the physical properties of lozenges, such as weight uniformity, hardness, friability, and tablet disintegration time. Thus, choosing the right ratio between mannitol and sucrose is important to produce quality lozenges.
Co-Authors Abdullah Syafiq Ahmadi Dewi Rahmawati Fitria Ayu Kusumaningtyas Rahma Dwi Novitasari Salsabilla Dhiya Atik Nuraini Shabrina Putri Arianti Yani Ambari