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All Journal Medali Jurnal : Media Dental Intelektual Padjadjaran Journal of Dentistry
S. Abdurrohman, Muhamat Muhtar
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The effect of brown algae (Sargassum sp.) gel on the number of osteoclasts in periodontitis rats S. Abdurrohman, Muhamat Muhtar; Praptiningsih, Rahmawati Sri; Yulistinawati, Yulistinawati
Padjadjaran Journal of Dentistry Vol 34, No 3 (2022): November 2022
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol34no3.39285

Abstract

ABSTRACTIntroduction: Alveolar bone resorption in periodontitis is caused by increased activation of osteoclasts, causing an imbalance of bone remodeling.  Periodontitis treatment can be done mechanically with Scaling and Root Planing and accompanied by metronidazole.  Antibiotics have long-term drawbacks and can cause allergies, thus requiring an alternative to natural topical drugs such as brown algae gel.  This study aimed to to analyzed the effect of brown algae gel (sargassum sp) on the number of osteoclasts of alveolar bone in periodontitis rats. Methods: The research method was a True Experimental with a pretest-posttest-only control group design. Rats were divided into three groups; negative control (K-) was not given any treatment, positive control (K+) was given metronidazole ties plus 25% concentration, and the treatment group (KP) was given brown algae gel (Sargassum sp) 75% concentration. Data were analyzed by Friedman and Kruskal Wallis test. Results:There was a significant difference in the number of osteoclasts on days 8, 10, and 12, the decrease in the number of osteoclasts was higher in the brown algae treatment group than the negative control group (p=0.051). In the positive control group, there was a significant difference in the decrease of the number of osteoclasts compared to the brown algae treatment group (p=0.029). The number of osteoclasts was significantly different on day 12 (p=0.026).Conclusion: Adhering brown algae (Sargassum sp.) gel decreases osteoclasts in periodontitis rats.Keywords: bone remodeling; bone resorption; brown algae gel (sargassum sp.); osteoclasts; periodontitis.
Aesthetic Treatment Of Maxillary Central Diastema Due To Differences In Teeth And Jaw Sizes With Removable Orthodontics S. Abdurrohman, Muhamat Muhtar; Hidayat, Saskia Aida; Mahardika, Christina; Putranto, Rama
Jurnal Medali Vol 8, No 1 (2026): Media Dental Intelektual February 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.8.1.32-38

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Background: The aesthetic treatment of maxillary central diastema due to differences in tooth and jaw size is an important component of orthodontic treatment. Tooth size and shape are crucial factors that affect the smile and face in treatment results. From an orthodontic perspective, evaluating the ideal mesiodistal width of teeth in relation to the upper and lower jaw arches is necessary to plan for proper occlusion, aesthetics, and functionality.Case: A 19-year-old woman came to RSIGM Sultan Agung complaining that her upper front teeth appeared spaced apart and affected her appearance. The patient's medical history showed that he was in good general health. Extraoral examination was within normal limits. Intraoral examination revealed a diastema between the upper central incisors, normal frenulum attachment, an overjet of 3.4 mm, and an overbite of 3.1 mm. Analysis of the working model revealed a positive arch length discrepancy in the upper jaw, while other analysis results were within normal limits. The etiology of the diastema in this case was the size of the available dental arch and normal tooth size. The patient underwent treatment for central diastema using removable orthodontic appliances equipped with active and passive devices, as well as additional finger spring components to mesialize teeth 11 and 12 and close the maxillary central diastemaConclusion: Esthetic treatment of maxillary central diastema caused by differences in tooth and jaw size can be performed using removable orthodontic appliances with additional finger spring components. Patient cooperation during treatment and retention appliances are necessary to achieve stable long-term orthodontic results
Co-Authors Hidayat, Saskia Aida Mahardika, Christina Rahmawati Sri Praptiningsih Rama Putranto Yulistinawati, Yulistinawati